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Biomedical subjects

A Falk

Publications and source records attributed to A Falk.

103 records · Page 6Linked to original sources
PubMed1978

Prophylaxis with isoniazid in inactive tuberculosis. A Veterans Administration Cooperative Study XII.

Based on a study indicating a significant rate of reactivation of tuberculosis in Veterans Administration patients with inactive disease, a cooperative study was initiated to determine the prophylactic effect of isoniazid on the rate of reactivation. A randomized double-blind study was designed, utilizing three regimens, two with isoniazid and one with placebo only. Two consecutive years of taking pills in one of the three regimens was followed by five years of observation. A total of 7,036 patients with inactive disease, some of whom had received prior chemotherapy, were entered into the study. Only 63 reactivations of tuberculosis were found, for a total rate of reactivation of 9/1,000 (less than 1%) over the seven-year period. Although no significant differences in the rate of reactivation were found among any of the regimens, there was a significant reduction in the rate of reactivation among those who had not received any prior chemotherapy and received isoniazid (INH) in this study, compared with those who received placebo only.

Antitubercular Agents↗
PubMed1977

Freud and Herzl.

Explore the source record for details and available documents.

Austria↗
PubMed1974

Border symbolism.

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Association↗
PubMedDate not supplied

Percutaneous treatment of thrombosed arteriovenous fistulae using the Gelbfish-Endovac aspiration thrombectomy device.

PURPOSE: To study the efficacy and safety of percutaneous treatment of thrombosed hemodialysis arteriovenous fistulae (AVF) using the Gelbfish-Endovac aspiration thrombectomy device (Gelbfish-Endovac). METHODS: From September 2003 to May 2004, twenty-nine percutaneous thrombectomy procedures were performed in 27 patients (median age of 67 years, 14 females) with thrombosed hemodialysis AVF using the Gelbfish-Endovac. Prior interventions, procedure time, anticoagulation, use of additional devices/thrombolytic agents, technical success, clinical success, complication rates, and patency at 30, 60 and 90 days were evaluated. RESULTS: Sixteen upper arm and 13 forearm AVF were declotted. Seventeen AVF had prior percutaneous interventions. Three AVF had not matured. Median AVF age was 9 months. Heparin was used in 14 procedures. Sixteen arterial lesions and 25 venous lesions were uncovered and treated. Two AVF required the additional use of the Arrow-Trerotola percutaneous thrombectomy device. One AVF underwent side branch ligation. No thrombolytic agents were used. Median procedure time was 70 minutes. Initial technical success was achieved in 24 AVF and clinical success was achieved in 22 AVF. Eleven complications occurred. Ten AVF remained open at 30 days, 10 at 60 days and 8 at 90 days without further interventions. With additional percutaneous interventions, 16 AVF remained open at 30 days, 16 at 60 days and 15 at 90 days. CONCLUSION: The Gelbfish-Endovac aspiration thrombectomy device is safe and efficacious for percutaneous declotting of AVF.

Journal Article↗
PubMedDate not supplied

Median nerve bisection: a morbid complication of a peripherally inserted central catheter.

Considering the reported safety, efficiency, and low cost of peripherally inserted central catheters (PICCs), they are increasingly preferred to central venous catheters for short-term delivery of medical therapies. Here, we report a case of severe median nerve bisection during PICC placement via a brachial vein. While such nerve damage is uncommon, the case indicates that when the brachial vein is selected as an access site over the basilic and cephalic veins, caution should be exercised during PICC placement since the brachial vein traverses in close proximity to the median nerve.

Arm↗
PubMedDate not supplied

Identity and name changes.

The theoretical literature as well as case material presented point to the intimate relationship of name changes to identity struggles. Names have strong affective value and symbolize an important part of a person's identity. The cultural and social value of a name may be secondary to the personal meaning of that name to the individual who in changing it will reveal an inner change in his sense of identity or an inability to integrate a diffuse sense of identity. The answer to "what's in a name?" may be "Identity's in a name."

Culture↗
PubMedDate not supplied

Comparison between sterile saline and tap water for the cleaning of acute traumatic soft tissue wounds.

OBJECTIVE: To find out if there were any differences in infection rates if acute traumatic soft tissue wounds were cleaned with tap water instead of sterile saline. DESIGN: Randomised study. SETTING: Emergency department at one city hospital. SUBJECTS: 705 consecutive patient with soft tissue wounds less than six hours old that did not penetrate a viscus, cavity, or joint and could be treated by primary suture. INTERVENTIONS: Randomly allocated to have the wound cleaned with either sterile saline or tap water in addition to debridement. MAIN OUTCOME MEASURE: Rate of wound infection, the presence of which was indicated by pus in the wound and prolonged healing. RESULTS: The infection rate in wounds cleaned with sterile saline was 10.3% compared with 5.4% in wounds cleaned with tap water (p less than 0.05). Infected wounds were significantly larger than uninfected ones (p less than 0.05) and more likely to be located on a lower extremity (p less than 0.05). There were no microbiological differences between the two groups, and no bacterial species grown from tap water was subsequently grown from an infected wound. CONCLUSION: Sterile saline should be replaced by tap water for the cleaning of acute traumatic superficial soft tissue wounds.

Acute Disease↗