[Anatomo-clinical findings in 7 cases operated on for cranial eosinophilic granuloma].
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Biomedical subjects
Publications and source records attributed to A Fabiani.
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Thrombotic thrombocytopenic purpura (TTP) during infectious diseases is a known, but rare event. In this paper a case of TTP associated with primary infection by Mycobacterium tuberculosis is described. Various therapeutic approaches were used with the patient: fresh frozen plasma infusions and plasma exchange, specific anti-tuberculous therapy, anti-platelet drugs and steroids. A complete remission occurred 3 months after the onset of the acute disease. A hypothesis on the pathogenesis of TTP might be an increased pro-coagulant activity of interleukin 1 (IL-1) on endothelial cells.
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The Authors describe zymographic characteristics of non specific esterases in human and rat brain and in tumors of the nervous system. Bound and soluble esterases were evidenced using substrate and inhibitor systems in association with detergent extraction. In normal nervous tissues the results confirmed previous observations on the identity of the gray and white matter esterases, except for minor quantitative differences. In brain tumors some peculiar pattern was particularly useful for biological interpretation of tissue differentiation and cell metabolism. The Authors show that the use of Triton X-100 extraction associated with suitable effectors allows a more correct classification of non specific esterases.
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