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Biomedical subjects

A Fabian

Publications and source records attributed to A Fabian.

25 records · Page 2Linked to original sources
PubMedDate not supplied

[Clinical course and epidemiological analysis of amyotrophic lateral sclerosis in Szczecin in 1986-1995].

49 patients diagnosed as amyotrophic lateral sclerosis (ALS), hospitalized between 1986-1995, inhabitants of Szczecin-City were included in this study. ALS was diagnosed according to WFN criteria. The control group consisted of 60 people. Men:women ratio was 1.57:1. The mean age at ALS onset was 53.2 years. The disease was most often present between 51 and 60 years. Only one ALS patient was observed in the group of patients aged 21-30 and in the group of individuals older than 70 years. ALS incidence was 0.9 per 100,000 inhabitants and its prevalence in 1995 was 2.7 per 100,000 inhabitants. The mean duration was 30.8 months and was slightly higher in women. The shortest duration was observed in the bulbar form of ALS--21 months. Patients with ALS had been exposed to head trauma and contact with animals more often than the average population. There is no difference between Szczecin and previously analysed Polish cities in the considered epidemiological parameters. No discrepancies of clinical picture and course of the disease were found in comparison with other reported by other authors.

Adult↗
PubMedDate not supplied

[Breast tuberculosis--a case report].

The authors report a case of breast tuberculosis in a 58-year-old patient in which the diagnosis was made with difficulty, initially the case being interpreted as a neoplastic process. This diagnosis should be considered in such cases. In our area, in the present tuberculosis endemic, the cases of tuberculosis with extrapulmonary localisation are more and more frequent.

Antitubercular Agents↗
PubMedDate not supplied

[Neurological deficits in patients with primary and secondary anticardiolipin syndrome].

27 patients (22 women, 5 men); age 17 to 56 yr. (mean age 37 yr.) were included in this study, 4 had primary antiphospholipid syndrome and 18 secondary antiphospholipid syndrome in the course of systemic connective tissue disease and in 5 cases increased levels of anticardiolipid antibodies were found which did not meet the criteria necessary for diagnosis of secondary antiphospholipid syndrome. The mean duration of the disease was 8 yrs. Among primary antiphospholipid syndrome patients two had ischaemic stroke, one migraine-like headache and seizures. 18 patients had lupus erythematosus, two mixed connective tissue disease, one rheumatoid arthritis, one Sjögren syndrome, one Behçet disease. In 55% of patients migraine-like headache, polyneuropathies, encephalophaties, stroke, seizures and vision disturbances were present. In 18.5% of patients EEG exam revealed focal lesions with tendency for generalisation. On brain stem auditory evoked potentials examination, in 11.1% of patients conductivity lesions in mesencephalon and pons were found, visual evoked potentials, in 11.1% of patients in visual tracts. In 37% of patients, neuropathy was found on EMG exam. Neurological symptoms are one of the most frequent disorders in systemic connective tissue disease associated with the presence of anicardiolipin antibodies.

Adolescent↗
PubMedDate not supplied

[Diagnostic difficulties in tumours of foramen occipitale magnum].

The reported case was diagnosed formerly as multiple sclerosis. On autopsy it was found that disseminated neurological symptoms were caused by a neurofibroma of the foramen magnum. The diagnostic difficulties in cases of tumours in this location are discussed.

Adult↗