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Biomedical subjects

A F Winder

Publications and source records attributed to A F Winder.

At least 91 records · Page 5Linked to original sources
PubMed1977

Laboratory studies in the management of soft contact lens use.

Laboratory procedures may be of great value in dealing with lens spoilation and in monitoring the state of the cornea during lens wear. Deposition of calcium-rich material remains the only defined non-mechanical process involved in spoilation although other forms of deposit and discolouration occur. Excess calcium levels in tear fluid are not a feature of contact lens wear, but changes in the sodium-potassium concentration ratio of tears are found. The basis for this effect is obscure but ratio changes may be useful empirical indices of corneal function.

Adolescent↗
PubMed1976

Evaluation of macrophage electrophoretic mobility (MEM) test as an indicator of cellular immunity in ocular tumours.

The macrophage electrophoretic mobility (MEM) test of Field and Caspary did not clearly separate patients with ocular neoplastic disease from those with inflammatory disease, although there was some indication of discrimination between choroidal melanoma and ocular inflammation. In our hands the test failed to give a reproducible result for the immunodiagnosis of ocular malignancy. The technique, however, seems to provide some indication of delayed hypersensitivity in experimental inflammatory eye diseases when relatively pure antigens are used.

Animals↗
PubMed1976

Human albinism.

Explore the source record for details and available documents.

Albinism↗
PubMed1975

Calcium deposition as a cause of spoilation of hydrophilic soft contact lenses.

A series of 75 spoilt soft lenses with opacities (mostly manifesting as discrete spots or as large areas of cloudiness, chalk-white in appearance) were subjected to histochemical, electron microscopical, electron probe x-ray microanalytical, x-ray diffraction, atomic absorption spectro-photometric, and biochemical analyses. The results showed that in many cases calcium was implicated in the deposit formation and that a broad correlation existed between the amount of calcium present and the degree of opacification. The possible mode of calcium deposition and resulting implications in lens intolerance are discussed. It is advocated that a search should be made for a modified or new soft lens material which does not permit calcium deposition, and that the medical practitioner should strive towards improved assessment of the systemic and ocular conditions which may help in identifying patients at risk of early lens failure.

Calcium↗