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Biomedical subjects

A F Smith

Publications and source records attributed to A F Smith.

At least 181 records · Page 10Linked to original sources
PubMed1973

Comparison of two-point (AutoAnalyzer II) with kinetic methods for transaminase assay.

The general performance of the Technicon AutoAnalyzer II method for the routine estimation of serum aspartate and alanine transaminase has been assessed and compared with that of the LKB reaction rate analyser. The results of the two methods correlate, there is little difference in precision, and running costs are comparable. Some of the relative advantages of the two types of analysis are discussed.

Alanine Transaminase↗
PubMed1970

Clofibrate, serum enzymes, and muscle pain.

Serum creatine kinas (C.K.), aspartate amino-transferase (G.O.T.), and alkaline phosphatase (A.P.) activities were measured in 211 men with serum cholesterol concentrations in the upper one-third of the normal distribution. Of these, 110 were receiving clofibrate and 101 were given identical capsules containing olive oil. These investigations were also carried out on 85 healthy men with low serum cholesterol levels not receiving clofibrate.No differences were observed in C.K. and G.O.T. activities between any of these groups; A.P. was significantly lower in the clofibrate-treated group. No significant alterations in C.K. occurred during serial observations made in 15 patients with ischaemic heart disease over a period of five months. No instance of myalgia or muscle stiffness was recorded in 452 men who had received clofibrate for one year.It is concluded that raised C.K. and G.O.T. concentrations and the occurrence of myalgia are uncommon accompaniments of clofibrate treatment.

Adult↗
PubMed1970

The production of calcium and magnesium during pancreatic function tests in health and disease.

Duodenal calcium and magnesium concentrations after pancreatic stimulation were measured in 25 patients with and without pancreatic disease. The concentration of both ions was higher in those with pancreatic disease, and furthermore these patients showed a different secretory pattern. These findings may be relevant to the aetiology of pancreatitis and to pancreatic calcification, and might be of diagnostic value.

Bicarbonates↗