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Biomedical subjects

A F Morey

Publications and source records attributed to A F Morey.

45 records · Page 3Linked to original sources
PubMed1994

Biopty gun testis needle biopsy: a preliminary clinical experience.

OBJECTIVE: To assess the reliability, safety and patient satisfaction of transcutaneous Biopty (Bard Urological, Covington, GA, USA) gun testis biopsies. PATIENTS AND METHODS: Nineteen young men who were referred for evaluation of azoospermia were included in the study. The procedure was performed in an outpatient setting, under local anaesthesia and without sedation. Two passes of the Biopty gun spring-loaded needle were performed unilaterally in each patient. RESULTS: An average of 38.9 seminiferous tubules were evaluable per patient. The procedure was extremely well-tolerated by all patients and most felt that the procedure was no more distressing than simple phlebotomy. CONCLUSION: Transcutaneous testis needle biopsy performed with the Biopty gun is safe, rapid and cost-effective. This technique may represent a viable alternative to the open method of testis biopsy.

Adult↗
PubMed1994

Proliferative activity as an adjunct in the diagnosis of prostatic adenocarcinoma.

Sixty-nine men underwent transrectal ultrasound-directed biopsy of the prostate. One biopsy core from each side of each gland was sent for DNA flow cytometric testing (138 total specimens). Results were correlated with findings from standard hematoxylin and eosin staining of other cores. Twelve patients (17.4%) had biopsies with histopathologic evidence of prostatic carcinoma. Of 57 patients (82.6%) with benign biopsies, two had stage A prostate adenocarcinoma noted on subsequent transurethral resection. Proliferative activity was calculated from DNA histograms by adding the percentage of nuclei in the proliferative (S and G2/M) phases of the cell-division cycle. Mean proliferative activity for the malignant group (19.08) was significantly higher (p < 0.001) than that of the benign group (13.43). Inflammation was associated with elevated proliferative activity scores among benign glands. Proliferative activity is an objective, easily obtainable indicator of the biological activity of a population of cells which, when elevated, may suggest a need for repeat biopsy in patients with otherwise normal prostate biopsies. Flow cytometry may have value as a complement to standard histologic analysis of transrectal core biopsies in the diagnosis of prostate cancer.

Adenocarcinoma↗
PubMed1993

The effects of exercise and activity on serum prostate specific antigen levels.

To determine the effects of exercise and activity on serum prostate specific antigen (PSA) levels, we studied an inpatient adult male population, and evaluated the PSA levels before and after a graded exercise stress test. We confirmed a prior finding showing a significant difference between inpatient and outpatient values, yet found that stressful exercise had no definitive effect on serum PSA values.

Adult↗
PubMed1989

Ectopic prostate tissue at the bladder dome.

A 71-year-old white man with asymptomatic microscopic hematuria had a sessile tumor at the dome of the bladder containing benign prostatic glandular tissue. Benign prostatic polyps occur commonly in the prostatic urethra and bladder neck as vestigial remains of embryonic prostatic elements. Ectopic prostatic tissue elsewhere is rare and has not been described previously arising at the bladder dome. The origin of prostate glands in this unlikely location is unclear. The clinical course of ectopic prostatic polyps at any location is benign, although local recurrence has been reported.

Aged↗
PubMed1988

Malpractice claims for urogenital injuries.

Precise information regarding patient injuries, claims and compensation in medical malpractice cases is scarce. This dearth is especially evident among cases citing injury to the genitourinary system. In an effort to explore the topic of iatrogenic urogenital damage 3,454 malpractice claims were reviewed and an analysis of 122 cases involving urogenital injury is presented. The 2 types of claims that predominated were negligent surgery, and failure to diagnose and treat urogenital disease. Nonurological practitioners were the focus of allegations of negligence in two-thirds of each type of claim. Certain surgical procedures and clinical shortcomings in a wide range of specialties were identified as being prevalent causes of malpractice claims for urogenital injuries. The correlation between money paid to claimants and specific types of injury also was examined. Suggestions are offered regarding ways to reduce the risk of malpractice liability.

Diagnostic Errors↗