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Biomedical subjects

A F Hefti

Publications and source records attributed to A F Hefti.

31 records · Page 2Linked to original sources
PubMed1991

[Fluoride excretion in schoolchildren with differing systemic fluoride care].

The aim of the present study was to collect data on urinary fluoride output in 8-16-year old students exposed to either drinking water fluoridation (DWF), or domestic salt fluoridation (DSF). Spot urine samples were collected in the canton of Basel-Stadt (DWF, n = 123), in the canton of Berne (DSF, n = 264), in the county of Davos (DSF, n = 241), and in the city of Winterthur (DSF, n = 40). Furthermore, fluoride concentrations were determined in plasma samples drawn from 33 students from Winterthur. The urinary fluoride concentrations were higher in Basel and Davos (0.62 +/- 0.35 mg/l; 0.61 +/- 0.42 mg/l) than in Berne and Winterthur (0.46 +/- 0.42 mg/l; 0.50 +/- 0.31 mg/l). A relatively high natural fluoride content (0.3 mg/l) in the drinking water explained the difference in urine fluoride concentration between students from Davos and the two other regions with domestic salt fluoridation (Berne, Winterthur). The average fluoride concentration in plasma was 12.7 +/- 3.8 ng/ml. We concluded that, in general, the supply with fluoride consumed with fluoridated domestic salt is close to the level obtained with drinking water fluoridation. However, in areas with very low systemic fluoride supplementation through the drinking water this level might not be reached with salt as the only source of systemic fluoride. Also, the data confirmed the safety of domestic salt fluoridation.

Adolescent↗
PubMed1990

[The border seal in restorations of class-V lesions with glass ionomer cement and composite (the sandwich filling)].

In 9 patients, 60 class V restorations were evaluated clinically and by scanning electron microscopy. All lesions were treated with glass-ionomer combined with composite resin. In 27 fillings (group A) the glass-ionomer lining cement was etched, whereas in 33 fillings (group B) the composite material was applied directly on the unetched glass-ionomer liner. Clinically, the retention of the fillings after one year was 100%. The margins of the fillings were checked with different explorers and found to be acceptable. Scanning electron microscopy of the margins of the fillings showed disappointing results. One week after placement of the fillings, only 16.2% (group A) and 7.4% (group B) of the cervical margins in dentin were rated perfect. After one year, even more cervical bond failures were observed. 9.7% perfect margins were found in group A, 3.2% in group B. Etching of the glass-ionomer liner had no influence on the cervical bond failure of the class V fillings.

Acid Etching, Dental↗
PubMed1989

The effectiveness of root debridement in open flap procedures by means of a comparison between hand instruments and diamond burs. A SEM study.

The goal of the present in vivo study was to evaluate human roots by means of scanning electron microscopy (SEM), after treating the root surfaces either with conventional hand instruments or with newly developed diamond burs. Peculiar root anatomy often makes perfect instrumentation with hand instruments difficult or impossible. On 20 teeth destined for extraction because of severe periodontitis, the root surfaces were exposed by mucoperiosteal flap procedures. Ten roots were then planed using fine curettes, and 10 were instrumented using diamond burs. Following extraction, the root surfaces were stained and photographed. Stained areas were examined by SEM. On the 20 test teeth, 79 surfaces were evaluated. From these, 381 stained zones were checked by SEM for the presence of bacteria. A total of 216 stained areas from teeth treated by hand instruments was evaluated; 15 of these (6.9%) contained bacteria. Of roots treated by diamond burs, 165 stained areas were evaluated; 9 (5.5%) exhibited bacteria. Thus, both methods resulted in root surfaces that were essentially bacteria-free.

Adult↗
PubMed1989

[Acceleration of orthodontically induced tooth movement through the local application of prostaglandin (PGE1)].

A preliminary study was designed to assess the effect of prostaglandin E1 on tooth movement. In 5 patients palatal attachments were bonded on corresponding upper left and right premolars which were to be extracted later in the course of routine orthodontic treatment. A transpalatal elastic exerted reciprocal force on the teeth. Following local anaesthesia, 0.1 ml of a 0.01% (w/v) PGE1 solution in saline was injected under the mucoperiosteum palatal to the test tooth and 0.1 ml saline palatal to the contralateral control tooth. Injections were repeated at weekly intervals. On average, the PGE1-treated teeth moved 3 times faster than the controls but the rate of movement differed individually. Clinical and x-ray examinations of the teeth involved in the study as well as the surrounding tissues showed no evidence of pathologic changes. No negative side effects were noticed by the patients. Despite positive experiences, this treatment is not to be recommended for use in dental offices yet.

Adolescent↗
PubMed1989

[The incidence of plaque and gingivitis in schoolchildren of the Davos region].

The aim of the present study was to collect basic material for planning and executing a program for the prevention of caries and gingival inflammation in children. A total of 275 schoolchildren aged 8, 10 and 12 years were examined by 3 calibrated examiners in Davos Dorf and Davos Platz. The degree of plaque was measured according to the Pl-I of Silness and Löe on all permanent teeth. Gingivitis was measured using the SB-I method according to Mühlemann and Son. Oral hygiene: the eight- and ten-year-old children from Davos Dorf exhibited a significantly smaller Pl-I than their counterparts in Davos Platz. A significantly different (p less than 0.02) oral hygiene was also found between girls and boys of age 12. Gingivitis: The degree of gingivitis was minimal in the youngest age group. A significantly greater inflammation (p less than 0.03) was found in the 10-year-old group from Davos Platz. There was no discernible difference measured in the 12-year-old group between Davos Dorf and Davos Platz, but there was a distinguishable difference observed between the sexes (p less than 0.02).

Child↗
PubMed1987

The effect on early plaque formation, gingivitis and salivary bacterial counts of mouthwashes containing hexetidine/zinc, aminefluoride/tin or chlorhexidine.

This study was designed to investigate the effectiveness of mouthwashes containing hexetidine/zinc (HZA) or tin (ASF) in inhibiting plaque formation and gingivitis in humans. 24 dental students and assistants participated in the study (latin square design) with 7-day test periods. They rinsed twice daily for 1 min with one of the following formulations: HZA = 750 ppm hexetidine/750 ppm zinc acetate, ASF = 100 ppm aminefluorid/310 ppm stannous fluoride, CHX = 0.1% chlorhexidine and M = negative control. Plaque accumulation was determined planimetrically and gravimetrically. Gingivitis was evaluated with the papillary bleeding index. Total colony forming units and S. mutans counts were estimated from saliva samples. The results showed that HZA and CHX almost completely inhibited plaque accumulation and gingivitis. ASF was less effective than HZA and CHX but still reduced plaque significantly compared to the negative control. Furthermore, CHX reduced salivary S. mutans counts.

Amines↗
PubMedDate not supplied

Osseointegrated dental implants as alternative therapy to bridge construction or orthodontics in young patients: seven years of clinical experience.

Young patients often require fixed bridgework or orthodontic therapy in cases of traumatic tooth loss or congenitally missing teeth. Dental implants represent an alternative to the more conventional treatment methods. We report positive experience over a seven-year period with 42 titanium Ha-Ti implants in 34 patients aged 9 to 18 years. Fourteen implants were placed into prepared tooth sockets immediately after traumatic luxation of anterior teeth in 12 patients aged 9 to 18 years (median age 16). An additional 22 patients (median age 15.5, range 11 to 18) also received implants (N = 28), but these were placed only after healing of extraction sites, or as substitutes for congenitally missing teeth. Implants remained in situ for an average of 7.7 months before loading. During the healing period, three implants were lost due to additional trauma and one became infected. The 38 remaining implants osseointegrated and since have been loaded for five to 79 months in successful function. There was no difference between immediate and delayed implants in clinical success. These experiences demonstrate that appropriate, versatile, osseointegrated implants can provide a successful treatment method for young patients, without damaging adjacent teeth.

Adolescent↗
PubMedDate not supplied

Factors affecting cyclosporine-induced gingival overgrowth in pediatric renal transplant recipients.

The purpose of this research was to study the occurrence of gingival overgrowth (GO) in children after kidney transplantation and to investigate the relationship of GO to medical and dental parameters. Forty-nine kidney transplant patients taking the immunosuppressive drug cyclosporine A (CsA) were evaluated for plaque (PI), calculus (CI), gingival inflammation (GI), probing depth (PD), width of keratinized gingiva (GW), and gingival overgrowth (GO). Blood trough levels and oral dosages of CsA were obtained from medical charts on the day of examination. Most (77.5%) subjects exhibited GO, suggesting that GO is a frequent problem in children and adolescents ingesting CsA. GI, PD, and GW were found to be statistically significantly greater in subjects with GO than in those without GO. CsA dose/day was not significantly different between subjects with GO and those without GO. CsA dose/kg body weight and blood trough levels of CsA were significantly higher in subjects without GO, but the average length of time subjects without GO had been ingesting CsA was only 1.3 months, compared with an average 3.5 years for subjects with GO. The results indicate that in young subjects, duration of CsA ingestion may be the most critical factor related to eventual GO development.

Administration, Oral↗