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Biomedical subjects

A F Deutman

Publications and source records attributed to A F Deutman.

At least 73 records · Page 4Linked to original sources
PubMed1986

Ligneous conjunctivitis.

The case history is given of a woman of 65 (in 1973) with a granulomatous conjunctival inflammation in the right eye and chronic recurrent polyps on the vocal cords. Several times, granulomatous tissue was removed from the conjunctiva of the right eye but the result was recurrences at shorter intervals. Seven years after the onset in the right eye the left eye became affected. Various treatments, both systemic and local, were tried without success. The histological diagnosis of ligneous conjunctivitis was not made until 1981. Treatment with the known remedies for ligneous conjunctivitis was not successful. At the end of 1984 treatment with Imuran (azathioprine) was started. Since that time the patient has been practically free of recurrent granulomatous tissue on the conjunctiva and vocal cords. The treatment of ligneous conjunctivitis with Imuran has not previously been reported in the literature.

Aged↗
PubMed1986

Atypical sector pigmentary dystrophy.

The authors describe a family with atypical sector shaped pigmentary dystrophy in two generations with transmission from father to son. A review of the literature is given.

Adult↗
PubMed1986

Idiopathic sub-retinal neovascular membranes in the macula (hemorrhagic macular choroidopathy of young adults). Clinical report and effectiveness of laser treatment.

Twenty-six patients with idiopathic sub-retinal neovascular membranes (INVMs) located within the posterior pole were examined. Clinical and fluorescein angiographic features of these patients are described. Follow-up ranged from 2 to 96 months (mean 16.5 months). Laser treatment was performed according to the location of the neovascular membrane: 7 out of 9 eyes (77%) increased their final visual acuity or stabilized after Argon blue-green laser photocoagulation (INVMs further than 200 microns from the center of the fovea). Krypton red light laser treatment was performed in 13 eyes with juxta-foveal and sub-foveal INVMs: following treatment 10 eyes (77%) improved by 2 or more Snellen lines or maintained their pre-treatment visual acuity. Because of the fact that the Krypton laser was not yet available, 5 patients were not treated: all of them had sub-foveal (3) or juxta-foveal INVMs (2). The natural history of 4 cases (80%) showed an increase in the final visual acuity in 3 eyes and a steady state in one eye. Pathogenesis and treatment outcome of the disease are finally discussed.

Adolescent↗
PubMed1985

Evolution of benign concentric annular macular dystrophy.

In 1974, Deutman described a family with an autosomal dominantly inherited macular dystrophy that he termed "benign concentric annular macular (bull's-eye) dystrophy." Ten years later, we performed a follow-up examination. Some patients complained of deterioration of visual acuity, night vision, and color vision. The macular dystrophy had progressed. The fundus periphery was more involved and in two patients there were bone corpuscle-like pigmentations. Electrophysiologic examination showed increased photoreceptor dysfunction with equal involvement of the rod and cone system. The patients had an acquired type III blue-yellow color vision defect with pseudoprotanomaly.

Adult↗
PubMed1985

Rips of the retinal pigmentepithelium.

A rip or rupture of the detached retinal pigment epithelium (RPE) with subsequent retraction of that layer is an often misdiagnosed affection of the posterior pole of the eye. The histologic appearance of this entity has to our knowledge not yet been published, but the fundus aspect and fluorescein angiography show that the focal absence of the pigmentepithelial layer is very likely. A rip is only seen in older age and it always appears in a detached RPE that often exists in combination with other features of a senile macular degeneration. Mostly the rip arises spontaneously but it may develop sometimes directly after laser coagulation of the detached RPE.

Aged↗
PubMed1984

Iris angiography after cataract extraction and the effect of indomethacin eyedrops.

To test the efficacy of topical indomethacin eye drops in preventing cystoid macular edema (CME) postcataract extraction, iris fluorescein and fundus fluorescein angiography were performed in two series of eyes that underwent intracapsular cataract extraction; 25 control eyes and another 25 eyes receiving indomethacin eye drops. In the latter group, 1% indomethacin eye drops were given three times a day, from 1 day preoperatively to 4 weeks postoperatively. In these two groups, there was a statistically significant difference in the findings on iris fluorescein angiography in the early and late period. There appeared to be a correlation between the degree of dye leakage on iris fluorescein angiography and the occurrence of CME. Fundus examination showed 6-9 weeks postoperatively perifoveal vascular leakage in 28% of the control group and in 8% of the indomethacin group. The results show from this study support the theory that prostaglandin form an etiological factor of CME.

Aged↗
PubMed1983

Acute multifocal ischaemic choroidopathy and the choriocapillaris.

Acute multifocal ischaemic choroidopathy (AMIC) seems to be a better name than acute posterior multifocal placoid pigment epitheliopathy (A.P.M.P.P.E.). Fluorescein angiography indicates obstruction of the precapillary choroidal arterioles leading to non perfused choriocapillaris lobules and focal swelling of the retinal pigment epithelium at the site of the lesions. Furthermore in many fluorescein angiograms of human patients the specific mosaic pattern of the choriocapillaris can be observed, which was described in monkeys by Hayreh & Baines (7). The choroid has, indeed, an endarterial system. The special conditions in which a well-defined appearance of the choriocapillaris occurs are listed.

Choroid↗
PubMed1982

Visual disturbances during pregnancy caused by central serous choroidopathy.

Three patients had during pregnancy visual disturbances caused by central serous choroidopathy. One of them had a central scotoma in her first and second pregnancy. The 2 other patients had a central scotoma in their first pregnancy. Symptoms disappeared spontaneously after delivery. Except for the ocular abnormalities the pregnancies were without complications. The complaints can be misinterpreted as pregnancy-related optic neuritis or compressive optic neuropathy, but careful biomicroscopy of the ocular fundus should avoid superfluous diagnostic and therapeutic measures.

Adult↗