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Biomedical subjects

A Epstein

Publications and source records attributed to A Epstein.

6 recordsLinked to original sources
PubMed1992

The embryonically active gene, unkempt, of Drosophila encodes a Cys3His finger protein.

The unkempt gene of Drosophila encodes a set of embryonic RNAs, which are abundant during early stages of embryogenesis and are present ubiquitously in most somatic tissues from the syncytial embryo through stage 15 of embryogenesis. Expression of unkempt RNAs becomes restricted predominantly to the central nervous system in stages 16 and early 17. Analysis of cDNAs from this locus reveals the presence of five Cys3His fingers in the protein product. Isolation and analysis of mutations affecting the unkempt gene, including complete deletions of this gene, indicate that there is no zygotic requirement for unkempt during embryogenesis, presumably due to the contribution of maternally supplied RNA, although the gene is essential during post-embryonic development.

Amino Acid Sequence↗
PubMed1978

Speech audiometry.

Two aspects of speech audiometry, namely, the speech reception threshold and the speech discrimination scores, have been discussed in the light of their development and present day administration. Evidence was presented to forego the concept of phonetic balance in discrimination test messages for the preferable attributes of familiarity and equated list difficulty. Campbell's redistribution of the W-22 word lists was proposed as an available solution to one of these parameters. Some delineation of the single "maximal" discrimination score's relation to the prediction of the hearing impaired individual's ability to understand continuous discourse was offered. Diagnostic implications of speech audiometry were not treated.

Audiometry↗
PubMedDate not supplied

Earmold configuration: relation to speech discrimination scores.

Choice of the earmold for a particular individual is perhaps the most subjective of all decisions made by clinicians in hearing aid fitting. The four earmold designs used in this study were standard-long, standard-short, belled-vented, and cavernous. Conslusions were: 1) performance differences in earmolds of contrasting design can be assessed by discrimination scores with monosyllabic word lists of equal difficulty; 2) among the physical measures taken of the earmold-receiver systems, frequency-response overall range (HAIC) ranked the devices in agreement with group responses to a word identification task; and 3) these data offer a basis for endorsement of the standard-long and cavernous-short earmold types over the other two with their superiority evident in each of the discrimination categories of excellent, good, and poor.

Acoustic Impedance Tests↗