Search PubMed⌕ Search

Biomedical subjects

A Elisa

Publications and source records attributed to A Elisa.

4 recordsLinked to original sources
PubMed1994

[Primary malignant melanoma of the male urethra. Case report and discussion of the literature].

We report the case of a 77-year-old man who presented with a polypoid tumor in the distal urethra. It was excised, and a histological diagnosis of malignant melanoma was made. The patient had no history of previous cutaneous biopsies or suspicious pigmented lesions; therefore, the melanoma was considered to be primary in the urethra. The patient declined therapy and died 28 months later with local tumor progression. The autopsy revealed a widespread metastatic disease. The male urethra is rarely the primary site of a malignant melanoma. This event has so far been described in about 45 patients. The case is discussed in view of the pertinent literature.

Aged↗
PubMed1989

Chronic immune thrombocytopenic purpura--immunological analyses of a patient pre- and post-HIV seroconversion.

A seven year follow-up of immune parameters is reported for a patient with chronic immune thrombocytopenic purpura (ITP) pre and post human immunodeficiency virus (HIV) seroconversion. Therapies such as intravenous IgG, prednisone, vincristine, or Ciclosporin A had no clear-cut beneficial effect on platelet counts. A long-term normalization of platelet counts was achieved by splenectomy. At splenectomy the patient was seropositive for HIV, most likely transmitted by blood products received half a year prior to laparatomy. Mean plasma levels of the second component of complement, C2, were half of the normal values prior to and within the lowest normal range post HIV seroconversion. Nevertheless, the T cell-dependent B cell response to HIV, which is dependent on the activation of C3 via the classical pathway of complement, was normal: Western blot analysis of total IgG and of IgG subclass responses to individual HIV antigens proved to be unimpaired.

Antigen-Antibody Complex↗