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Biomedical subjects

A Eggert

Publications and source records attributed to A Eggert.

At least 55 records · Page 3Linked to original sources
PubMed1984

[Intraoperative pancreas puncture cytology].

In the case of 10 to 15% of surgical patients with a pancreatic disorder an intraoperative diagnosis had to be made when a preoperative diagnosis had not yielded a definite result. Fine needle aspiration biopsy ( FNAB ) of the pancreas provided the basis for intraoperative differentiation of malignant and benign pancreatic processes. 244 pancreatic biopsies were carried out in 100 patients. It was possible to make a statement in 99% of the cases, with 65 malignant and 35 benign changes. In 83% the cytological diagnosis was correct; the method yielded incorrect-negative results in 7% of the cases. In 9% the presence of tumour cells was only suspected. There were no incorrect positive cancer diagnoses. FNAB caused no postoperative complications. Intraoperative bleeding after FBAB had to be stopped with a suture in one case. Transitory, asymptomatic hyperamylasemy must be expected in 25% of the patients after FNAB . This diagnostic technique is recommended in preference to the histological tissue removal methods because of its low risk factor. At least 2 biopsies of the suspect area with 2 smears are required, as a training in this diagnostic technique.

Biopsy, Needle↗
PubMed1984

[Liver biopsy in surgery of the gallbladder].

Biopsy of the liver with the menghini needle was done as a routine diagnostic procedure during surgery in 581 cases. During earlier decades morphological changes of the liver could be demonstrated by that procedure in 80-100% of the patients. In contrast such changes could be found only in 55% of our cases; in 5,5% these changes were severe. From these numbers it should be concluded that liver biopsy during gall bladder surgery is not necessary as a routine procedure. If patients are selected for biopsy on the basis of history, ultrasonography, laboratory data and intraoperative microscopical liver findings this procedure is necessary only in 14% of the cases, complication rate being 0,09%. In this particularly selected group changes of the liver can be found in 90,4%, severe changes in 33% of the cases. Pathological changes of the liver are likely to occur in 65-91% of patients with complicated gall stone disease and/or accompanying diseases like diabetes, obesitas, alcoholism, or a history of hepatitis. In this particular group biopsy and histological examination during surgery seem to be indicated as it was the case before.

Biopsy↗
PubMed1982

The pathologic implication of duodenal diverticula.

In a prospective study of 80 patients with duodenal diverticula and calculous biliary tract disease, bacteriocholia with typical intestinal bacteria was found in 51 of 71 patients, whereas, in cholelithiasis without duodenal diverticula, this complication was present in 278 of 809 patients. With an increasing distance between duodenal diverticula and the papilla of Vater, the rate of bacteriocholia decreases. Advancing age of the patients results in the augmentation of bacteriocholia. Bacteriocholia on the basis of duodenal diverticula seems to present an additional pathogenic factor for inflammatory biliary tract disease and pancreatitis. Consequently, the pathologic value of juxtapapillary duodenal diverticula is much more prominent than has so far been reported.

Age Factors↗
PubMed1982

[Staged lavage therapy in diffuse peritonitis].

Sequential lavage is introduced as a new treatment for severe diffuse purulent peritonitis. Following surgical removal of the focus and intraoperative intraabdominal lavage, the sequential lavage technique was applied with length of treatment dependent on the severity of each case. Data from 21 patients were recorded for the study. Subject lethality was 19%. Three patients survived the so-called "incurable triad".

Drainage↗
PubMed1982

[Pancreatogastrostomy in papillary cancer].

In the therapeutic treatment of ampullary cancer in 11 patients pancreatogastrostomy was substituted for pancreato-jejunal anastomosis. Pancreatogastrostomy is a simpler technique and is more reliable than sutures with the small intestine. In the postoperative phase the anastomosis can be monitored at any time by radiological and endoscopic examination. However, examination of lipase in the gastric juice shows that even these anastomoses are closed in two patients as early as the second year after the operation. The frequent closure of anastomoses speaks in favour of the discontinuation of the exocrine function of the pancreas during the operation by means of occlusion jelly together with pancreatogastrostomy for the transitory protection of the resection surface of the pancreas.

Ampulla of Vater↗
PubMed1981

[Starch granulomas caused by glove powder].

Simultaneously with the introduction of new surgical gloves with heavily powdered outside surfaces, complications repeatedly occurred after laparotomies. Four patients were compelled to undergo a second operation, during which peritoneal fibrous adhesions and foreign body granulomas of omentum were found. After resection of the omentum, healing proceeded without disturbance. Five different types of surgical rubber gloves were examined by scanning electron microscopy. In addition, the effect was evaluated of different commonly applied preoperative rinsing procedures for gloved hands. The amount of powder found on the outside of regularly used gloves varied between 0.059 and 0.287 g. The effect on the proper healing process by starch powder deposits found on the outside of surgical gloves as well as upon optimal cleansing of the surgical teams' hands will be discussed.

Adolescent↗
PubMed1980

[The excretion of methylmethacrylate from bone cement through the lungs (author's transl)].

By using a continuous infra-red monitoring technique, it could be shown that in 42 patients undergoing TEP surgery methylmethacrylate is excreted through the lungs. The amount of monomer eliminated in the exhaled air is less following acetabulum implantation than following femoral shaft implantation. The concentration of monomer in the exhaled air is strongly influenced by measures such as femoral shaft drainage, washing the implantation site with icewater and lengthening the cement mixing time which reduce the transfer of the monomer. Pulmonary elimination of MMA-monomer takes 20 min and is very fast.

Acetabulum↗
PubMed1980

[Serotonin and dumping syndrome (author's transl)].

5-hydroxyindole acetic acid, xanthurenic acid and kynurenin, --that is to say the major metabolites of serotonin, were measured in the urines of 31 patients with dumping syndrome. Serotonin concentrations were measured as well in peripheral venous blood before and after a glucose load in 47 patient with dumping syndrome. All values measured were in the normal range. Comparison of serotonin levels in peripheral and portal venous blood yielded normal results as well. It is therefore concluded, that serotonin does not play an essential role in the etiology of the dumping syndrome.

Dumping Syndrome↗
PubMed1980

[Prevention of surgical wound infections by means of ring drapes].

In order to test the efficiency of wound protecting ring drapes and incisional drapes we carried out a prospective study of 283 patients, who underwent larger operations of the gastrointestinal tract from 1975 to 1979. Whilst complications of wound healing following operations of the upper gastrointestinal tract were not reduced, a reduction of the rate of secondary wound healing by 20% was achieved after operations on the large bowel. Overweight did not cause a higher rate of wound sepsis as it is usually the case when wound protecting drapes are not used. A further significant reduction of complicated wound healing could be observed after preoperative systemic application of antibiotics. This effect could not be stated when antibiotic prophylaxis was started after the operation.

Bacteriological Techniques↗
PubMed1979

[Bacteriological findings in patients with cholelithiasis and duodenal diverticuli].

In a prospective study of 70 patients with duodenal diverticula and calculous biliary tract disease, bacteriocholia with typical intestinal bacteria was found in 69%, whereas in cholelithiasis without duodenal diverticula this complication was present in 30% of the cases. With growing distance between duodenal diverticula and the papilla of Vater the rate of bacteriocholia decreases. Rising age of patients results in augmentation of bacteriocholia. Bacteriocholia on the basis of duodenal diverticula seems to present an additional pathogenetic factor for inflammatory biliary tract disease in 69% and for pancreatitis in 20% of the cases. Consequently the pathologic value of diverticulas close to the papilla of Vater is more prominent than reported so far.

Bile↗
PubMed1978

Archival storage of clinical laboratory data.

This paper describes a data-base system for the maintenance of cumulative clinical data. A unique aspect of this data base is its ability dynamically to alter its two-level format to create an alternative three-level hierarchical structure in order to optimize retrieval efficiency. The relative advantages of these two types of data-base structures are discussed and examples of their use in clinical resrarch are presented.

Chemistry, Clinical↗
PubMed1977

[Intraoperative temperature measurements at the acrylic bone/cement interface in total hip endoprosthetic (TEP) implantations (author's transl)].

Temperature measurements are reported effected by aid of thermocouples enclosed in tubules in TEP-implantations of the hip. Two techniques were employed: the first using as acrylic bone cement Palacos or Sulfix-6 without concomitant cooling, the second Palacos after precooling of the femur with crushed ice/water mixtures. The first method yielded, at the acrylic bone cement/bone interface, temperatures above the coagulation point of the protein (56 degrees C). The novel technique of implantation is described, i.e. the cooling of the bone with ice-water prior to the cement implantation. This technique provides a means of restricting the average temperature at the aforesaid interface to 45 degrees C.

Bone Cements↗
PubMed1977

[The significance of intraoperative bacteriological findings in operations on the gallbladder and biliary tract (author's transl)].

The symptomless bacterial contamination of the biliary tree is apt to be the origin of general or local postoperative complications. The present retrospective study of 369 bilary operations with intraoperative bacteriologica investigations yielded the following results: septic wound complications were found in 9% of the cases with bacteriocholia against 3.5% in the cases with abacterial bile. In geriatric patients with complicated gallstone disease the bacterial contamination of the bile exceeds 50% of all cases. The importance of an adequate antibiotic treatment for this group, starting intraoperatively, is stressed.

Adult↗
PubMed1977

[An analysis of factors which can be influenced in geriatric surgery (author's transl)].

A retrospective study has been made of 1457 surgical patients over 70 years of age in three one-year periods (1960/61, 1969, 1973). While the average age remained 77, there has been changes in the frequency of diseases leading to hospitalisation. Degenerative lesions and casualties have increased. There are more elderly patients undergoing major surgery. On the contrary the mortality has reduced to 7.8%. The results of geriatric surgery are influenced by previous and concomitant diseases, the surgical lesion and the type of therapy. Suggestions for reducing the number of emergency operations are discussed. When necessary smaller palliative operation which improve the quality of life should be considered instead of major curative surgery. Surgery in the aged is a speciality and requires simultaneous consideration of various factors.

Age Factors↗
PubMed1977

[Additional information regarding periarticular ossifications after total hip replacement (author's transl)].

Residual monomer originating from acrylic bone cement is not the origin of periarticular calcifications after hip joint replacement. This has been demonstrated by gaschromatografic detection of monomeric methylmethacrylate in the liquid of the joint space. Up to 200 microng/ml monomeric MMA could be demonstrated in the first days after the operation only. The concentration of residual monomeric MMA in the bone cement is 1% to 4%. It is deminished time dependently by diffusion of the molecule in the surrounding tissue. All determined concentrations of monomeric MMA in the joint liquid are below the toxic range for tissue demage.

Calcinosis↗
PubMed1977

[Geriatric aspects in operative treatment of intertrochanteric fractures (author's transl)].

On the basis of published data and of 702 osteosyntheses carried out using the Pohl sliding hip screw, the authors come to the conclusion that the mortality rate in geriatric patients is not correlated to the method of osteosynthesis used. Of utmost importance are immediate operation and early mobilisation. The osteosynthesis of intertrochanteric fractures in geriatric patients must facilitate early loading of the fracture site. This paper compares intramedullary nails, pertrochanteric blade plates, Y-nails and sliding hip screws, and contrasts these with the authors' own experience with the Pohl sliding hip screw.

Age Factors↗