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Biomedical subjects

A E Ljunggren

Publications and source records attributed to A E Ljunggren.

7 recordsLinked to original sources
PubMed1992

Fibrinolytic activity as a predictor of the outcome of prolapsed intervertebral lumbar disc surgery with reference to background variables: results of a prospective cohort study.

In a prospective study 122 patients with a slipped lumbar disc and no previous surgery were preoperatively examined for fibrinolytic activity. Surgical results for these patients were evaluated 12 months postoperatively by clinical overall assessment. In a multiple linear regression analysis fibrinolytic variables, euglobulin clot lysis time and plasminogen activator inhibitor 1, were shown to have predictive value regarding outcome of surgery; that is, normal fibrinolytic activity favors a satisfactory outcome and vice versa. Background variables and lipid profile were also recorded preoperatively. Body mass index, gamma-glutamyl transpeptidase, triglycerides and smoking were of statistical significance in relation to euglobulin clot lysis time and plasminogen activator inhibitor 1. Postoperative fibrinolytic re-examination of 20 patients seem to confirm that patients at risk of surgical failure have a prolonged depression of fibrinolytic activity.

Cohort Studies↗
PubMed1979

Clavicular function.

This is a survey of the functional variation of the clavicle, in particular with regard to its adaptability, the bone being an essential link in the shoulder girdle. The presence of a clavicle, and its shape, size and position are discussed from the point of view of stability and mobility, and the role of the bone regarding circulation, pulmonary ventilation and muscular tension is pointed out. It is stated that the clavicle contributes significantly to the stability of the shoulder girdle, and that in man the presence of this bone represents an increase in the degree of freedom of the upper extremity mobility pattern, dependent on the transversal shape of the thoracic diameter. The precondition for the clavicle to function appropriately is that its curvature fits in with the ligamentous pull.

Clavicle↗
PubMed1976

The tuberositas tibiae and extension in the knee joint.

In all 56 tibiae from Lapps and 56 from Norwegians have been studied. These ethnic groups represent different weight bearing situations. Variables dealing with the extension in the knee joint are dealth with. The bone is mainly studied in the AP and the ML planes. The material is analyzed statistically. The distribution form is examined and the deviations from normality are found to be moderate. Chiefly positive skewness occurs. Platykurtosis is found equally often as leptokurtosis. The deviations from a standard normal distribution are not supposed to affect the results significantly. There is a non-systematic pattern of distribution. The variability is generally lower in Lapps than in Norwegians. The variability is about the same in linear and angular variables and in indices. In linear variables females and Lapps show lower mean values than males and Norwegians, respectively. Lapps show the largest indices. In linear variables, contrary to in angular variables and indices, the sex differences exceed the differences between the ethnic groups. As a rule sex differences are largest in Lapps. The variations of the tuberositas tibiae are supposed to be in particular the results of muscular forces in bone remodeling. The relationship between the habitual knee position and extension is discussed.

Computers↗
PubMed1976

Variations in the relationship between the diaphysis and the epiphyses of the tibia.

In all 56 tibiae from Lapps and 56 tibiae from Norwegians have been studied. These ethnic groups represent different weight bearing situations. Variables expressing adaptation to non-axial loading are dealt with. The bone is mainly studied in the AP and the ML planes, as well as in the three dimensional space. The material is analyzed statistically. The distribution form is examined and the deviations from normality are found to be moderate. Mainly positive skewness occurs. Platykurtosis is found as often as leptokurtosis. The deviations from a standard normal distribution are not supposed to affect the results significantly. There is a non-systematic pattern of distribution. The variability is generally lower in Lapps than in Norwegians. The standard deviation shows highest numerical values in indices, lowest in linear variables. Systematic group differences, especially in similar variables, are supposed to be of greater importance than isolated differences. The variables giving deviations from the reference planes or the diaphyseal axis, show the largest and the consistent left-right differences. In linear variables Lapps and females show lower mean values than males and Norwegians, respecitvely. In linear variables giving deviations from the reference planes, in angular variables and in indices, Lapps usually show the highest mean values. Lapps tend to show larger sex differences in variables giving deviations from the reference planes or the diaphyseal axis. However, the sex differences within the Lapps are small. The variations of the tibia are supposed to be the results of mechanical factors in bone remodelling. The epiphyseal-metaphyseal parts tend to have a constant shape, the adaptations to non-axial loading predominantly appearing in the diaphysis. The relation between the weight bearing line and the diaphyseal axis is discussed, particularly regarding the ML stability mechanism of the knee joint. The occurrence of torsion and its influence upon the AP and ML projected values regarding the relationship between the epiphyses and the diaphysis are discussed.

Biometry↗
PubMed1975

Biostatics of the tibial shaft.

In all, 56 tibiae from Lapps and 56 tibiae from Norwegians have been studied. These ethnic groups represent different weight bearing situations. Only measurements referring to the diaphysis are presented. The bones are studied in the AP and ML planes and at different transverse sections. The material is analyzed statistically. The distribution form is examined. Chiefly positive skewness occurs. Platykurtosis is found twice as often as leptokurtosis. A differentiated pattern of distribution seems to be the case regarding measurements in the lower extremities. This corresponds to the influence of variable hereditary and external factors. Divergencies from standard normal distribution is compared with differences between groups. In some cases differences are influenced by platykurtosis and skewness. Divergence from standard normal distribution could not be traced back to measuring errors, special features of the bone or special sex characteristics. The divergencies are not supposed to affect the results to any noteworthy extent. Female Lapps show small variances, female Norwegians great variances. In linear variables Lapps generally show smaller values than Norwegians, females smaller values than males. Regarding linear measurements, sex differences are a little more marked than differences between the two ethnic groups. The opposite is the case regarding the angular measurements and the indices. The sex differences in linear measurements are smaller in Lapps than in Norwegians. The opposite is the case regarding the length of the bone. In Lapps, angular measurements and indices show no significant sex differences. Regarding linear measurements, differences between the ethnic groups are mostly due to differences between the males. The opposite may be said about the indicnes. The variations of the tibia recorded and discussed in the present paper are the results of mechanical factors influencing the basic processes in functional bone remodelling. The periosteal ossification is particularly involved in the dimensions of the shaft, the epiphyseal cartilage in the length dimensions. Particularly important is the relation between the weight bearing line and the diaphysial axis of the bone, and the muscles activated by variation is this relation.

Adult↗