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Biomedical subjects

A E Cameron

Publications and source records attributed to A E Cameron.

53 records · Page 3Linked to original sources

High frequency jet ventilation - its use in respiratory insufficiency. Two case reports.

High frequency jet ventilation was used in two patients with severe pulmonary disease, one of whom was deteriorating and the other not improving on a conventional regime of antibiotics, physiotherapy and intermittent positive pressure ventilation. In our first case high frequency jet ventilation was achieved using one side of a double lumen endotracheal tube, whilst intermittent positive pressure ventilation was applied to the other side. In the second case a specially designed endotracheal tube with a distal jetting orifice was employed. In both cases there was marked improvement in chest X-ray appearance, arterial blood gas analysis and clinical condition, permitting resumption of spontaneous ventilation, extubation and eventual discharge from the Intensive Therapy Unit.

Humans↗

Gas exchange in abdominal cavity during laparoscopy.

Gas exchange occurring in the abdominal cavity during laparoscopy, using carbon dioxide as the insufflating gas, was investigated in 25 female patients being ventilated with 66.6% nitrous oxide and 33.3% oxygen. The gas remaining in the abdomen at the end of the procedure was collected and measurements were made using an infrared spectrometer, a paramagnetic analyser and a mass spectrometer. The mean duration of the laparoscopy was 9.5 minutes and the mean volume of carbon dioxide delivered was 6.8 litres. Nitrous oxide concentration in the abdomen was found to increase significantly with the duration of the procedure, varying from 1.4% to 12.8% with a mean of 4.3% (s.d. +/- 2.4). Oxygen concentration measured from 0.1 to 1.8% with a mean of 0.7% (s.d. +/- 0.4). Nitrogen concentration varied from zero to 1.8%, having a mean concentration of 0.8% (s.d. +/- 0.5). Carbon dioxide content was from 85.7 to 99.6% with a mean concentration of 94.2% (s.d. +/- 3.1).

Abdomen↗

Spinal analgesia using bupivacaine 0.5% plain. Variation in the extent of the block with patient age.

Bupivacaine 0.5% plain solution was used to produce spinal analgesia on 63 occasions. In 33 patients a fixed dose of 4 ml injected at the L2/3 interspace at 0.5 ml/second produced an extent of analgesia which was directly related to patient age (p les than 0.005). The latency was 17.3 minutes (SD 8 . 4) and duration of action was 286 minutes (SD 62). A second group receiving only 1 ml of solution had a much shorter duration of action (mean 154 minutes, SD 30). In 90% of patients the analgesia obtained was fully sufficient for surgery to be performed and no form of analgesic supplementation was given. On two occasions no analgesia occurred at all. Bupivacaine 0.5% plain proved to be an effective agent for subarachnoid block. The extent of analgesia was, however, poorly predictable, and even with low doses unacceptably high level of block were sometimes achieved.

Adult↗

Abdominal wound closure: a trial of Prolene and Dexon.

The incidence of wound infection, burst abdomen and incisional herniation after a vertical abdominal incision was studied in a prospective trial comparing polypropylene (Prolene) with polyglycolic acid (Dexon). Wounds were closed by interrupted mass suture with an optional reinforcing continuous closure of the anterior rectus sheath. A total of 347 patients was studied, randomly allocated to suture with either Prolene or Dexon. The two groups were well matched for known risk factors. Dehiscence occurred in 0.6 per cent of patients overall and at 6 months 5.7 per cent of cases had an incisional hernia, although many of these were asymptomatic. There was no difference in the rate of infection, disruption or herniation between the two suture materials.

Abdominal Muscles↗