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Biomedical subjects

A E Bharucha

Publications and source records attributed to A E Bharucha.

41 records · Page 3Linked to original sources

Prevalence of Parkinson's disease in the Parsi community of Bombay, India.

A door-to-door survey was carried out to screen a community of 14010 people (Parsis living in colonies in Bombay, India) for possible neurologic diseases. High school graduates, social workers, and medical students administered a screening questionnaire that had been shown in a pilot survey to have a sensitivity of 100% for identifying those with Parkinson's disease. Neurologists used defined diagnostic criteria to evaluate individuals positive on the screening survey. There were 46 people (25 men, 21 women) who suffered from Parkinson's disease (328.3 cases per 1000 population). The age-specific prevalence ratios increased consistently with age. Age-adjusted prevalence ratios were slightly higher for men.

Age Factors↗

Prevalence of stroke in the Parsi community of Bombay.

A door-to-door survey of 14,010 Parsis living in colonies in Bombay, India, screened people for possible neurologic diseases. High school graduates, social workers, and a medical student administered a questionnaire that had been shown in a pilot study to have a sensitivity of 100% for identifying persons with stroke. Neurologists used defined diagnostic criteria to evaluate those who were positive on the screening survey. One hundred eighteen persons (57 men, 61 women) suffered from stroke (842.3 cases/100,000 population). The age-specific prevalence ratios increased with age for both sexes and for each age group. Age-adjusted prevalence ratios were slightly higher for men than for women. The most common type of stroke was ischemic (114 cases).

Adolescent↗

Case-control study of completed ischemic stroke in the Parsis of Bombay: a population-based study.

All eligible adult cases of completed ischemic stroke (N = 112) derived from a prevalence survey of the Parsi community in Bombay, India, served as the basis of a case-control study of risk factors. The stroke morbidity rate in this group was similar to that reported for North America. A control subject free of stroke was selected randomly from the same population and matched to each case by age and sex. Information was obtained on various risk factors. Hypertension, both by history (odds ratio = 10.8) and by examination (odds ratio = 2.1), had a statistically significant association with stroke (p less than 0.01). This is one of the first community-based case-control studies of stroke in a large developing country.

Adult↗

Prevalence of multiple sclerosis in the Parsis of Bombay.

We carried out a door-to-door-survey to screen a community of 14,010 people (Parsis living in colonies in Bombay, India) for possible neurologic diseases, and used defined diagnostic criteria to evaluate people who tested positive on the screening survey. There were three clinically definite cases of multiple sclerosis (21/100,000). This is the first prevalence survey for multiple sclerosis in a large developing country.

Humans↗

Prevalence of epilepsy in the Parsi community of Bombay.

A door-to-door survey was carried out to screen a community of 14,010 people (Parsis living in colonies in Bombay, India) for possible neurologic diseases. High school graduates, social workers, and medical students administered a screening questionnaire that in a pilot survey had a sensitivity of 100% for identifying persons with epilepsy. Neurologists used defined diagnostic criteria to evaluate individuals positive on the screening survey. Sixty-six persons (43 males, 23 females) suffered from epilepsy (4.7 cases/1,000). Of those, 50 (34 males, 16 females) had active epilepsy (3.6 cases/1,000). The age-specific prevalence ratios remained fairly constant for each age group except for a small peak in the group aged 20-39 years for all epilepsy cases combined. Age-adjusted prevalence ratios were higher for males. The most common seizure type was partial (36 cases). The most frequently associated conditions were cerebral palsy and mental retardation. The majority of individuals were receiving medication as of prevalence day (47 cases).

Adolescent↗