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Biomedical subjects

A E Beris

Publications and source records attributed to A E Beris.

At least 19 recordsLinked to original sources

Total hip arthroplasty for avascular necrosis and degenerative osteoarthritis of the hip.

Although several studies of various treatment modalities have been reported during the past decade, osteonecrosis of the femoral head remains a difficult therapeutic problem. Total hip replacement which is reserved for patients showing collapse of the femoral head, usually shows poorer results in patients with osteonecrosis compared with those with osteoarthritis. Uncemented total hip arthroplasty was performed on 29 patients with avascular necrosis of the femoral head and 29 patients with degenerative osteoarthritis. After a mean followup of 7.6 years and 7.1 years for the two groups of patients, only one failure was observed in one patient with osteonecrosis. Clinical evaluation after cementless total hip arthroplasty in both groups of patients revealed improvement in all parameters. Postoperatively, pain improved from 1.4 to 5.1, walking ability from 3.4 to 5.3, and range of motion from 4.5 to 5.5 in patients with osteonecrosis, and pain improved from 1.2 to 5.3, walking ability from 3.2 to 5.4, and range of motion from 3.1 to 4.7 in patients with osteoarthritis. Thigh pain was observed postoperatively in only two and three patients treated for osteonecrosis and osteoarthritis, respectively. The present results using cementless arthroplasty seem to be somewhat better than those reported for cemented arthroplasty in patients suffering from osteonecrosis. The clinical and radiographic findings after noncemented arthroplasty in patients with osteonecrosis of the femoral head and in patients with degenerative arthritis of the hip were similar in the two groups.

Adult

Idiopathic osteonecrosis of the medial femoral condyle. Classification and treatment.

Idiopathic osteonecrosis of the medial femoral condyle is a well recognized cause of spontaneous, sudden onset of severe pain, usually at the anteromedial aspect of the knee joint. At the Department of Orthopaedic Surgery of the University of Ioannina, 105 knees in 101 patients were evaluated and treated for idiopathic osteonecrosis of the medial femoral condyle. The disease was found to follow a four-stage course, which consisted of a progression from no radiographic findings (Stage I), to a slight flattening of the medial condyle (Stage II), followed by the appearance of a radiolucent lesion (Stage III), and finally, articular cartilage collapse (Stage IV). Although Stages I and II potentially were reversible, Stages III and IV were associated with irreversible destruction of the subchondral bone and articular cartilage. Although bone scan is a nonspecific diagnostic modality, it was helpful in establishing diagnosis in the early stages of the disease. Conservative treatment was found appropriate for the first two stages, whereas surgical management was effective for patients with Stages III and IV. Specifically, osteotomy was useful for patients younger than 60 years of age with limited necrotic lesions, whereas unicompartmental arthroplasty was effective in older patients with more extensive lesions. Total knee arthroplasty can be reserved for cases where the disease has expanded to the lateral compartment.

Aged

Surgical treatment of malleolar fractures. A review of 144 patients.

Malleolar fractures are one of the most common fractures faced in orthopaedic surgery. The results from a consecutive series of 144 malleolar fractures during a 10-year period that were classified and treated according to the AO system are presented. Assessment of outcome was done using the scoring system of Baird and Jackson, which is based on subjective, objective, and radiographic criteria. Excellent and good results were achieved in 107 of the 144 patients surgically treated. Overall, excellent and good results were obtained in almost all unimalleolar fractures, but were significantly less in bimalleolar fractures. There was no difference in outcome achieved between Weber C and Weber D fractures. The presence of a large bony fragment or dislocation also significantly affected the final outcome. Posttraumatic osteoarthritis was found to be associated significantly with poor clinical results, bimalleolar fractures, and unsatisfactory surgical reduction.

Adolescent

Reflex sympathetic dystrophy of the upper extremity. Clinical features and response to multimodal management.

The weight of available evidence suggests that reflex sympathetic dystrophy (RSD) is a complex clinical entity that (1) occurs predominantly in young adult women; (2) has five clinical types but presents most frequently as minor traumatic dystrophy; (3) has primary signs and symptoms (e.g., pain, edema, stiffness, and discoloration) that are expressed highly in each clinical type, whereas secondary signs and symptoms are variable; (4) responds well to treatment, regardless of its clinical type; and (5) is managed best when treatment is started early. It can be concluded that RSD is a multifaceted disease that responds well when managed with a multimodal treatment program aimed at the various interacting components of the disorder. The recognition and documentation of the variation of the clinical features of RSD may allow for its earlier diagnosis and treatment and thus significantly improve the chances for a successful outcome.

Analysis of Variance

Scoliosis elasticity assessed by manual traction: 49 juvenile and adolescent idiopathic cases.

We assessed preoperative curve elasticity in 49 consecutive patients with juvenile or adolescent idiopathic scoliosis who were operated on with Harrington distraction rods. Preoperatively, the curve was determined from posteroanterior radiographs taken in the standing position and in the supine position, with traction. In the latter, the radiographs were taken at the moment of maximal traction when one technician applied traction to the ankles and another to the wrists. The scoliotic curve in the 10 patients with juvenile scoliosis averaged 59 degrees and 32 degrees in the standing and supine positions with traction, respectively. Immediately postoperatively, the curve averaged 19 degrees. 39 patients with adolescent scoliosis had a scoliotic curve which averaged 58 degrees in the standing position and 32 degrees in the supine position with traction. The mean postoperative measurement was 21 degrees. These findings suggest that manual traction is a simple and reliable means of predicting the minimal correction of the scoliotic curve to be expected, using Harrington distraction rods.

Adolescent

Load tolerance of tibial plateau depressions reinforced with a cluster of K-wires.

The efficacy of subchondral Kirschner wires in enhancing load tolerance of the tibial plateau articular cartilage was examined in a biomechanical study of cadaveric tibias. Seven patterns of K-wires were evaluated under axial loading equivalent to the maximum loading of the knee during normal gait. Subchondral K-wire reinforcement of tibial plateau depressions significantly enhanced load tolerance. This suggests that a subchondral cluster of K-wires in the treatment of tibial plateau fractures may protect the articular cartilage from the loss of reduction resulting from the forces applied to the knee during non-weight-bearing motion.

Analysis of Variance

Major ablative procedures in orthopaedic surgery.

In the presence of the notable progress in limb-sparing techniques afforded by the developments in microsurgery and musculoskeletal oncology, major ablative surgery of the extremities still remains a last-resort, yet powerful tool in managing patients with primary tumors in whom wide excision is not possible, as well as in cases with severe trauma to the limbs. During the last thirteen years, eight major ablative procedures were performed at the Department of Orthopaedic Surgery of the University of Ioannina Medical School. Seven out of the eight procedures were performed in patients with primary malignant tumors either because the anatomical location or multiple recurrences of the tumor did not allow removal by wide local excision or by amputation at a lower level. In one patient, the procedure was related to a severe, mangling trauma. Four illustrative cases of the eight major ablative procedures performed are reported to highlight the current indications of this rarely used, complex, and extensive surgery. The characteristic cases presented are: hemipelvectomy in a patient with chondrosarcoma of the pelvis, disarticulation of the hip in a patient with a malignant histiocytoma of the supracondylar area of the knee, forequarter amputation in a patient with a basal cell carcinoma of the axilla, and disarticulation of the shoulder in a patient with an incomplete nonviable amputation at the level of the shoulder girdle associated with severe damage to the brachial plexus and axillary artery. After a five to over a ten year follow-up, six of the eight patients who where subjected to major ablative procedures are doing well and are satisfactorily active. These cases reflect the dilemma that orthopaedic surgeons geons still face in selecting limb salvage or major ablative surgery in cases of aggressive malignant tumors to severe trauma.

Amputation, Surgical

Two-level dorsal dislocation of the little finger.

The case of an elderly man who suffered simultaneous interphalangeal joint dislocation in one finger as a result of a hyperextension force on both the distal and proximal interphalangeal joints is presented. This case differs from the few reports of this type of injury in the literature both in its mechanism of injury and time to reduction. Most reports have been in athletes who are actively involved in a sport, whereas the present case was the result of a fall. Also, successful reduction was achieved almost 2 weeks postinjury, indicating that, even with this amount of delay, these injuries can be effectively treated with closed reduction.

Accidental Falls

Osteoid osteoma in the differential diagnosis of persistent joint pain.

We report 20 cases (13 male and 7 female), mean age 21 years) of juxta-articular osteoid osteoma. The distribution of affected joints was as follows: hip joint (7 cases), knee joint (2 cases), ankle joint (2 cases); iliosacral joint (2 cases), lumbar spine (2 cases), carpus (2 cases), shoulder (1 case), second metacarpal (MCP; 1 case) and first metatarsal (MTP; 1 case). The duration between the onset of symptoms and diagnosis varied from 8 months to approximately 4 years. In juxta-articular osteoid osteoma, the clinical picture and the radiographic findings are often atypical, and this may lead to misdiagnosis and delayed definitive treatment. In young patients with persistent undiagnosed pain, the possibility of an osteoid osteoma should be considered. When the clinical picture is suggestive but radiological findings are negative, we must proceed to further investigation with bone scintigraphy and computed tomography. These examinations should be repeated 1 year after the onset of symptoms because initially negative findings may become positive at a later date. When the diagnosis of an osteoid osteoma is confirmed, surgical excision leads to complete relief of the symptoms.

Adolescent

Current indications for single digit replantation.

The functional outcome of 67 successfully replanted single digits (excluding the thumb) involving 31 complete and 36 incomplete nonviable amputations was found to be strictly related to the level of the amputation. While the survival rate was higher in patients with incomplete nonviable amputations (89 percent), compared to those with complete amputations (81 percent), the ability of the patient to use their digit was almost uniform among both groups of patients. All except 2 of the 9 digits with complete amputations at the level of the proximal phalanx or at the proximal interphalangeal joint (PIP) resulted in limited motion (less than 20 degrees-30 degrees) at the PIP and distal interphalangeal (DIP) joints. Only 9 from the group of patients with incomplete nonviable amputations at the proximal phalanx exceeded flexion greater than 40 degrees at the PIP joint. From these results, we conclude that the indications for replantation of a single digit amputation should be as follows: 1) amputation distal to the insertion of the flexor digitorum sublimis; 2) ring injuries type II and IIIa; and 3) amputations at the level of or distal to the DIP joint.

Adolescent

Complete versus incomplete nonviable amputations of the thumb. Comparison of the survival rate and functional results.

81 patients with 84 complete (55) or incomplete (29) nonviable amputations of the thumb were studied to compare the survival rate and functional results between the two groups. 3 of these patients had bilateral thumb amputations. Of the 55 completely amputated thumbs, 43 survived (78 percent), while of the 29 incomplete nonviable amputations, 25 were salvaged (86 percent). Excluding patients with an amputation at the level of or distal to the interphalangeal (IP) joint, motion at the IP joint which did not exceed 40 degrees flexion even when a secondary procedure was done, did not show a statistical difference between the 2 groups. Average two-point discrimination was 14 mm for patients with complete amputations and 11 mm for patients with incomplete nonviable amputations. We conclude that incomplete nonviable amputations of the thumb are associated with a higher survival rate and better sensibility than complete thumb amputations, while motion at the IP joint does not differ between the two groups of patients.

Activities of Daily Living

Alternative techniques for restoration of bony segments in digital replantation.

We present our experience from 108 partially or totally amputated digits in 87 patients which were replanted or revascularized successfully by the Orthopaedic Microsurgical Team at the University of Ioannina Medical School in Greece, during the period from 1978 to 1994. The majority of the patients were men involved in occupational accidents. Bone shortening always preceded the osteosynthesis and the vessel anastomosis, and most of the available methods for osteosynthesis were used, including small plates, single lag screws, crossed Kirschner wires, a combination of intraosseus cerclage wires and Kirschner wires, and intramedullary Kirschner wires. Our findings suggest that the most appropriate method for bone fixation in digital replantation is the insertion of one intramedullary Kirschner wire, supplemented by another wire which is inserted at the end of the procedure. This technique was found superior for the following reasons: 1) it's simplicity and the speed of the technique reduced the ischemic time; (2) less bone exposure was required; (3) less skeletal mass was needed for fixation; and (4) prior to the insertion of the second Kirschner wire, rotation of the replanted part was possible if it was necessary to re-align the vessels or to correct any rotational deformity.

Amputation, Traumatic

Nonviable injuries of the tibia.

Management of severe open fractures and non-viable injuries of the tibia remain both difficult and controversial. The orthopedist must carefully assess the injured limb in order to determine whether it should be salvaged or amputated. The difficult operative procedure requires thorough knowledge of microsurgical techniques necessary to repair vascular and neural injury. Over a 10 year period, 13 patients with non-viable, open fractures of the tibia underwent limb salvaging attempts using identical treatment protocol. 5 of the 13 limbs were salvaged, while 8 limbs were later amputated, because of either failure of revascularization or severe infection. 2 patients died; one with good circulation in the limb because of a massive pulmonary embolism 5 days postoperatively and the other because of severe septicemia 13 days postoperatively.

Adolescent

Latissimus dorsi free tissue transfer for coverage of extensive soft tissue defects.

15 latissimus dorsi free flap transfers were performed at the University of Ioannina Medical School during a 3-year period. Soft tissue defects in the upper (3) and lower (12) extremities resulting from trauma, septic pseudoarthrosis, osteomyelitis, open type IIIb fractures, incomplete amputations and tumor or unstable scar resection were covered by myocutaneous flaps in 6 cases and muscle flaps with split thickness skin grafts in 9 cases. Complications included pressure ulcer, infection hematoma and massive lung embolism. The results of the present study in which 13 of the 15 flaps were successful, suggest that an "orthoplastic" approach in covering soft tissue defects is beneficial.

Adolescent

Application of silicon tissue expanders for the direct or indirect coverage of soft tissue defects in the extremities.

In a 2 year prospective study, 17 tissue expanders were placed on the extremities of 17 patients. The aim was to cover soft tissue defects in the forearm of 8 patients after chinese flap dissection, which was used either as a free or reversed flap. In 8 of the remaining patients, the expanded skin was placed directly on the affected region as a local fasciocutaneous flap. In 1 patient it was determined intra-operatively that the prepared extended skin was not necessary to treat the patient. The tissue expander was successfully used to cover skin defects, both directly and indirectly, in the lower extremity (7 cases) and in the upper extremity (9 cases). Neither infection nor necrosis was observed in the flaps and the cosmetic results, particularly in the forearm, were satisfactory.

Adolescent

Management of ulnar nerve injuries.

Ulnar nerve injuries are common in young people. When there is a delay in the diagnosis and surgical management, the results are usually poor and can be permanent. Nerve grafting procedures were carried out in 85 patients with ulnar nerve injuries and 30 patients with both ulnar and median nerve injuries between 1981 and 1992. The patients could be divided into three categories according to the level of the trauma. Group A with injuries in the carpal area consisted of 43 cases with ulnar nerve injuries and 30 cases with both ulnar and median nerve injuries. Group B comprised 25 patients with ulnar nerve injuries in the area of elbow due to bone fractures. Group C comprised 18 patients with ulnar nerve injuries in the upper arm area. The quality of the functional results was closely related to the age of patients with better results in younger people and to early post-traumatic management of the injury. This was particularly notable in group C where, although there was high nerve damage, young patients and patients with early treatment generally had a better response than patients with lower ulnar nerve lesions. In contrast, we found that in cases of delay in surgical procedures for mixed nerve damage, the response was poor.

Adolescent

Microsurgery in children.

Advances in microsurgical techniques have permitted replantation and reconstructive procedures to restore amputated or injured parts with a high degree of success in children. Despite this progress, some technical concerns remain. During a 15-year period, replantations were done in 53 children with major limb (18), hand (10), or digit (25) amputations. Even in patients with crush or avulsion injuries, the results suggest that replantation procedures are justified considering the superior recuperative ability in children. Free tissue transfer was used for reconstructive procedures in 26 children, including free flaps, vascularized bone transfers, nerve grafts, and toe-to-thumb transfers. The microsurgical success rate was 86.8% for replantation procedures and 96% for reconstructive procedures. Although the technical aspects and outcome of replantation attempts still differ between adults and children, there appears to be little difference in free tissue transfer. Thus, most replantation and reconstructive procedures can be attempted with a high possibility of success in children.

Amputation, Traumatic