Biomedical subjects

A E Acosta

Publications and source records attributed to A E Acosta.

8 recordsLinked to original sources

PubMed1997

Clinical parameters of tumescent anesthesia in skin cancer reconstructive surgery. A review of 86 patients.

OBJECTIVE: To describe and define the viability of using tumescent anesthetic technique (TAT) in skin cancer reconstructive surgery with good results and without adverse reactions. DESIGN: Phase 3 clinical trial. SETTING: The National Institute of Cancer in Bogotá, Colombia, is a national referral center with an institutional practice. PATIENTS: From June 1992 to June 1994, 86 ambulant patients, who were of low to middle socioeconomic class, were referred from oncology to dermatology for moderately complicated surgery. As outpatients, they underwent skin cancer surgery using the TAT. The 2-year, postoperative follow-up included only 81 patients, because 5 patients (5.85%) could not be reached. INTERVENTIONS: The following formula was used: 0.5 L of 0.9% sodium chloride, 0.025 L of 2% lidocaine (epinephrine 1:200,000), and 5-mmol/L of sodium bicarbonate. MAIN OUTCOME MEASURES: The primary study outcome measures were planned before the data collection began. Relevant age and sex data, skin cancer characteristics, and the type of reconstruction performed were tabulated for these patients. Photographs of the patients were taken. Patients were asked to rate the level of pain during the injection, during the surgery, and after the surgery. The amount of bleeding and the cosmetic results, were also evaluated. RESULTS: Anatomical distortion before surgery was present in all the patients. The level of pain and bleeding (no patients experienced severe pain or bleeding) was minimal, and visualization of the surgical planes was good during the reconstruction using the TAT. On average, the size of the surgical specimen was 6.12 cm2. On the first day after surgery, tumescence decreased by 90% in each patient. Only 1 patient had a complication, which was a hematoma, attributable to trauma rather than to the TAT. The cosmetic results were good in 90% of the patients. CONCLUSION: The TAT in skin cancer reconstructive surgery offers good results and minimal complications.

Anesthesia, Local↗

PubMed1981

Direct immunofluorescence on cytological smears in oral pemphigus.

Direct immunofluorescence was performed on washed oral epithelial smears from thirteen patients with pemphigus vulgaris, thirteen patients with other oral diseases and from ten subjects with clinically healthy oral mucosa. The intercellular deposition of IgG was observed on cytological smears from oral smears from oral lesions in all patients with other oral diseases and from healthy controls, did not show any fluorescence. Therefore, direct immunofluorescence on cytological smears may be of value in the diagnosis of pemphigus.

Aged↗

PubMed1975

Colonic neoplasms complicating ureterosigmoidostomy.

A benign reactive polyp developed at each ureteral implantation in the sigmoid colon following bilateral ureterosigmoidostomy for exstrophy of the bladder. The first polyp was discovered 23 years after the operation. The second polyp occurred 4 years later at the other ureteral orifice. Each polyp contained benign cystic glandular epithelium within the submucosa and the stalk. These submucosal cysts resembled colitis cystica profunda, except that they were confined to the pedunculated polyps. A complete review of the literature of neoplasms complicating ureterosigmoidostomy is presented. It is concluded that a benign or a malignant colonic tumor may develop at the site of the ureterocolic anastomosis many years later. Therefore, patients who undergo this operation should be followed for the rest of their lives.

Adenocarcinoma↗

PubMed1973