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A Dupuy

Publications and source records attributed to A Dupuy.

42 records · Page 3Linked to original sources
PubMedDate not supplied

[Acquired circinated ichthyosis revealing a lymph node tuberculosis].

BACKGROUND: Acquired ichthyosis usually reveals or is associated with an internal disease. The classical clinical aspect is vulgaris ichthyosis. We report a case of acquired ichthyosis, presenting original clinical features, revealing a lymph node tuberculosis. CASE REPORT: A 63-year-old male patient without past history of skin disease consulted for a generalized eruption. The eruption was composed of multiple erythemato-squamous plaques. The edge of the plaque was raised and circinated. Histologic examination of the edge and the centre of the lesion supported the clinical diagnosis of ichthyosis. The diagnosis of lymph node tuberculosis based on large inguinal nodes was confirmed by the fast acid-bacilli found in the lymph node. Initiation of antituberculosis therapy was followed by the rapid and complete disappearance of the skin lesions. DISCUSSION: We report a case of acquired ichthyosis with original clinical features and we propose to coin the term "acquired circinated ichthyosis". This entity was clinically distinct from ichthyosis vulgaris or pityriasis rotunda. This dermatosis was concomitant to lymph node tuberculosis and healed under antituberculosis therapy.

Antibiotics, Antitubercular↗
PubMedDate not supplied

[The value of radiological follow-up for stage III melanoma].

INTRODUCTION: The modalities of follow-up (frequency of consultations and interest of repeated radiological examinations) of patients presenting with glandular metastases of melanoma (stage III of the AJCC classification) have not reached a consensus. PATIENTS AND METHODS: Since 1995, we have proposed clinical follow-up every two months and radiological controls with a thoracic-abdominal-pelvic scan every 4 months, to patients at high risk of relapse for the early screening of an infra-clinical relapse. RESULTS: The median follow-up was of 16 months (range: 1 to 82 months). Eight patients out of 24 (33 p. 100) followed-up in this manner, had asymptomatic metastases discovered by the radiological examinations. Among these 8 patients, three presented with a an operable, single, metastatic localization and two patients underwent surgery. One patient relapsed 3 months later, the other was still alive without relapse 24 months later. DISCUSSION: Surgery remains the treatment of choice for all stages of melanoma. In the absence of clearly effective treatment of metastatic melanoma, the early discovery of an infra-clinical metastatic relapse presents two major advantages. The first is the discovery of a single, operable metastasis, as was the case in two of the patients out of 24. The second is to be able to suspend an eventual adjuvant therapy with interferon alpha, as soon as a relapse has been discovered.

Adolescent↗