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Biomedical subjects

A Dumont

Publications and source records attributed to A Dumont.

At least 91 records · Page 5Linked to original sources
PubMedDate not supplied

Cholinergic regulation of motilin release from isolated canine intestinal cells.

An in vitro model was developed to study the regulation of motilin release from its endocrine-producing cell. Enzymatically dispersed cells from canine duodenojejunal mucosa were separated by centrifugal counterflow elutriation to enrich motilin content. From the motilin-enriched cell preparation, the release of motilin was determined under stimulation with various agents. Carbachol dose-dependently stimulated the release of motilin from its producing cell. Bombesin, morphine, and erythromycin, recognized stimulants for motilin release in vivo, failed to influence the secretion of motilin in vitro. Serotonin, GIP, CCK, pentagastrin, cisapride, neosynephrine, isoproterenol, or muscimol were also ineffective in the in vitro model. The response to carbachol was abolished by atropine but was not affected by somatostatin, serotonin, secretin, CCK, or GIP. These results suggest that muscarinic receptors are present on the motilin cell membrane and that acetylcholine is a major regulator of motilin release.

Acetylcholine↗
PubMedDate not supplied

Prenatal diagnosis of a congenital bladder diverticulum. Case report and benefits of prenatal diagnosis.

A case of congenital bladder diverticulum diagnosed at 37 weeks of gestation (measured from the first day after the last day of the last menstrual period) is reported. Delivery took place 24 h later. A postnatal urologic work-up confirmed the diagnosis of asymptomatic congenital bladder diverticulum. The infant underwent laparotomic surgery at the age of 6 months, with an extravesical diverticulectomy and ureteral reimplantation. There were no complications. This is the first case reported in the literature of a prenatal diagnosis of a congenital bladder diverticulum. This new aspect allows early management and avoidance of the diagnostic meanders to which the discovery of a pelvic mass might lead, as well as the complications that can follow bladder diverticula.

Adult↗
PubMedDate not supplied

[The gastroduodenal peptic ulcerous disease (author's transl)].

After a brief history of gastroduodenal ulcer since the 19th century, the authors discuss the question of its uniqueness. Upon clinical, biological and genetic grounds, it seems possible to distinguish two different kinds of ulcers. Ulcers situated above the junction between fundic and antropyloric mucosae could possibly be the consequence of biliary reflux, while ulcers situated below this junction would be associated with hyperchlorhydria. Some properties of gastrin, which is responsible for Zollinger-Ellison syndromes I and II, are cited. Presently, gastrin cannot be considered as the primary cause of duodenal ulcer.

ABO Blood-Group System↗