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Biomedical subjects

A Donnet

Publications and source records attributed to A Donnet.

At least 37 records · Page 2Linked to original sources
PubMed1999

Primary meningeal fibrosarcoma: a particular neuroradiological presentation.

Primary meningeal fibrosarcoma is a rare malignant tumor of the central nervous system. About seventeen cases have been reported in the literature since 1980. We present the case of a patient whose initial neuroradiological manifestation of primary meningeal fibrosarcoma was an en plaque meningioma. Fifteen months later, he developed a dramatic clinical deterioration and coma. CT scan revealed a large frontal lesion. The mass was completely removed and histological examination was characteristic of meningeal fibrosarcoma.

Adult↗
PubMed1999

Food deprivation and refeeding influence growth, nutrient retention and functional recovery of rats.

The objective of this work was to determine the effects of starvation and refeeding on growth, nutritional recovery and intestinal repair in starved rats. Male Wistar rats, weighing 200 g, were starved for 3 d, then refed a soy-based diet for another 3 d. Normally fed rats were given the same diet and used as controls. The variables assessed were as follows: body weight gain and nitrogen retention during recovery after starvation; muscle glutamine concentration; tissue protein content; gut mucosa and liver glutathione levels; intestinal permeability to ovalbumin, lactulose and mannitol; and intestinal tissue apoptosis. Starvation was associated with lower muscle glutamine levels and intestinal mucosa impairment, including a lower content of mucosal protein, a higher level of oxidized glutathione, enhanced permeability to macromolecules and greater numbers of apoptotic cells. Refeeding for 3 d resulted in rapid repair of gut atrophy and normalization of not only intestinal permeability but also of the majority of metabolic markers assessed in other tissues. In conclusion, with the use of severely starved rats, we have established a reversible experimental animal model of malnutrition that might prove useful in comparing the effectiveness of different enteral diets.

Analysis of Variance↗
PubMed1998

[Diagnostic dyspraxia and frontal syndrome].

A 27-year-old ambidexter woman experienced a clinical and psychometric frontal syndrome associated with a partial callosal syndrome following transcallosal surgery for an intraventricular neurocytoma. She also complained of difficulties with her left hand which realized a particular form of diagnostic dyspraxia: there were specific features of an isolated dysfunction of the control of the realization of a program.

Adult↗
PubMed1997

Migraine with visual aura and photosensitive epileptic seizures.

A relationship between epilepsy and migraine has long been postulated, but the nature of this interaction is still debated. We observed this association in a 23-year old man with a history of migraine with visual aura who had seizures at age 15 years while watching television. Waking EEG was normal, but sleep recordings demonstrated posterior spike-waves during sleep. During intermittent photic stimulation (IPS), a photoparoxysmal response occurred, maximum in occipital areas. Brain magnetic resonance imaging scan was normal. Seizures did not recur after 4-year treatment with valproate. He is currently seizure-free, but continues to have rare migraine with visual aura. The role of spreading depression or of a putative dopaminergic failure in occipital cortex is discussed.

Adult↗
PubMed1997

[Left temporal meningioma disclosed by ipsilateral hemiplegia].

A 46 year-old woman presented with a weakness of the left side. MRI of the brain showed a left temporal meningioma, a left temporal lobe herniation and two high-signals in the right cerebral peduncle. The involvement of the pyramidal tract in the foot of the cerebral peduncle, in this case, results from temporal lobe hemiation. These findings are different from the mechanisms reported in other cases of ipsilateral hemiplegia. The ipsilateral hemiplegia syndrome was classically described by Ectors in relation to a meningioma of the foot of the third frontal circonvolution. Pathophysiological theories of ipsilateral hemiplegia are reviewed.

Brain Neoplasms↗
PubMed1996

[Cytomegalovirus encephalitis in an immunocompetent adult].

Cytomegalovirus encephalitis in immunologically normal patients is rarely reported in the literature. Only seven cases have been previously reported. CMV infection was diagnosed in a 24-year-old, immunologically normal female presenting a severe clinical picture due to encephalitis. Diagnosis was based on detection of CMV DNA in the CSF with the polymerase chain reaction. Administration of ganciclovir was followed by an immediate improvement.

Adult↗
PubMed1996

[Acute Weston Hurst necrotizing hemorrhagic leukoencephalitis].

The clinical and pathological findings of a 43-year-old woman, diagnosed as having acute hemorrhagic leukoencephalitis at postmortem examination, are presented. The acute hemorrhagic leukoencephalitis affects mainly young adults and is the most fulminant from of demyelinating disease. It is frequently preceded by a respiratory infection. Diagnosis is facilitated by CT scanning and MRI, which reveal the massive lesion in the cerebral white matter. Many cases terminate fatally in 2 or 4 days, but in others survival is longer. The pathological findings are distinctive.

Acute Disease↗
PubMed1995

Do the suprasellar neurenteric cyst, the Rathke cleft cyst and the colloid cyst constitute a same entity?

Two cases of entirely suprasellar cysts are reported. Total surgical removal was performed in both cases. Pathological and immunohistochemical profiles were consistent with neurenteric cysts, Rathke's cleft cysts or colloid cysts and was also in keeping with an endodermal origin. It is now admitted that these three kinds of cysts share similar histological and immunohistological features. We propose an hypothesis of common embryological origin from endodermal remnants.

Adult↗
PubMed1995

[Meningoradiculitis and bilharziasis].

A 55-year-old French man was admitted with acute retention of urine. Three days before admission he developed back pain, lower limb pain and weakness. He had last been in Nigeria 2 years previously. Schistosoma mansoni ova were identified on rectal mucosal biopsy. Our patient showed spontaneous clinical improvement. He was treated with Praziquantel and corticosteroids. The clinical manifestations of spinal schistosomiasis can be diverse, and there should be a high index of suspicion for all patients from endemic areas. Currently, praziquantel and corticosteroids are the drug of choice for Schistosoma mansoni infection.

Humans↗
PubMed1995

[Prodromic fit of laughter and prerolandic tumor].

We report a case of "fou rire prodromique" heralding a right hemispheric glioblastoma involving the prerolandic cortex. The clinicoanatomical correlations of this phenomenon are discussed.

Brain Neoplasms↗
PubMed1995

[Characterization of gestural disorders in primary progressive apraxia: diagnostic and nosographic contribution].

Five cases are reported of patients with so-called primary progressive apraxia, defined as a slowly worsening disturbance of gestural abilities, without other major cognitive changes during a long period, in relation to degenerative cortical atrophy. All five cases, as other cases in the literature, share the following common features: 1) asymmetrical onset of upper limb clumsiness, more often involving the left side, later involving the contralateral side and lower limbs; 2) after a variable delay, the occurrence of symptoms suggesting subcortical involvement (akinesia, limb stiffness, various kinds of movement disorders, dystonia, paresis of vertical gaze); 3) diffuse cortical atrophy typically more pronounced in the superior parietal cortex opposite to the first side affected. The unusual nature of apraxia in all these cases is pointed out and referred to as Luria's "kinesthaesic apraxia", ascribed to a loss of "selectivity" of distal elementary movements. This pattern of symptoms and their specific outcome could represent a distinct entity.

Aged↗
PubMed1994

Ectopic basisphenoidal craniopharyngioma: case report and review of the literature.

We report the case of a patient with a nasopharyngeal craniopharyngioma. The presenting symptoms included a diminished visual acuity, a dysmorphic syndrome, and impaired endocrine function. The computed tomography and magnetic resonance imaging scans showed a partially cystic tumor that had destroyed most of the craniofacial sinus and anterior part of the cranial base. The patient was operated on through a rhinoseptal approach. We found 14 similar cases in the available neurosurgical and otorhinolaryngologic literature. The pathogenesis of this tumor and more especially its origin from Rathke's pouch remnants or pharyngeal hypophysis are discussed.

Adult↗
PubMed1994

[Intradural hematoma of the foramen magnum associated with factor XIII deficiency].

A 50-year-old woman, with a history of IgG monoclonal gammapathy, presented with meningitis and intradural hematoma of the foramen magnum associated with factor XIII deficiency. The patient died postoperatively of diffuse haemorrhage. Inhibitors to factor XIII are extremely rare and are congenital or acquired. Patients with factor XIII inhibitor can experience severe bleeding, and many died of cerebral haemorrhage. The role of this defect is discussed. We recommend an extensive investigation of haemostasis for patients with both episode of haemorrhagic disorder and monoclonal gammapathy.

Factor XIII Deficiency↗
PubMed1994

[Meningioma of the floor of the temporal fossa. Anatomo-clinical study of 11 cases].

The authors present eleven cases of middle fossa floor meningiomas. They describe the anatomical and clinical features of these tumors in this rare localisation. They emphasize the strait anatomical relations with the cranial base, eight cases were inserted above the superior surface of the petrous bone, two above the endocranial face of the horizontal part of the greater sphenoid wing, one above the horizontal part of the temporal squama. Headache (6 cases) and memory loss (4 cases) are the most frequent clinical feature, seizures (2 cases) and neuropsychologic troubles were probably undervalued. Auditory signs were present in three cases. There was no visual defect and cranial nerve impairment. They insist on the necessity to obtain a complete preoperative temporal bone CT scan exploration. They think that a well advised surgical act is sufficient for these meningiomas inserted above weak structures and with good prognosis: there's no recurrence in this study with a follow up from 12 to 132 months.

Adult↗