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Biomedical subjects

A Dean

Publications and source records attributed to A Dean.

99 records · Page 6Linked to original sources
PubMedDate not supplied

Tongue flaps for reconstruction of the oral cavity.

Pedicled tongue flaps (anterior, posterior, double) have proved to be an effective method of repairing defects due to tissue loss in the oral cavity. Their central position, mobility, and excellent blood supply make the use of these flaps feasible in a variety of sites.

Adult↗
PubMedDate not supplied

Expression of red cell antigens by K562 human leukemia cells before and after induction of hemoglobin synthesis by hemin.

We studied the red cell antigens present on K562 human leukemia cells before and after induction of hemoglobin synthesis by hemin. The fetal antigens i, IF, and IT were detected on uninduced cells. While expression of both i and IT antigens increased after hemin induction, expression of IT was closely related to fetal hemoglobin synthesis as determined in experiments in which the induction was reversed. The EnaFR, NVg, and T antigens of glycophorin A were also present on uninduced cells. In contrast, the M and Pra antigens of glycophorin A, the Kell system antigens, and the P1 antigen became detectable only after hemin induction. Antigens of other major red cell systems were not detected.

Adult↗
PubMedDate not supplied

An ecologic analysis of psychosocial stress and heart disease in British Columbia.

Cardiovascular disease is the leading cause of death in Canada. However, much heart disease incidence cannot be explained by known risk factors, and evidence points to the potential role played by the psychosocial environment. This study involves an ecologic analysis exploring the relationships between psychosocial stress and ischaemic heart disease (IHD) in British Columbia. First, data from the Canada Health Promotion Survey correlated stress indicators (i.e., education, marital status) with self-reported stress levels. Results showed gender differences in stress. Stage II consisted of a multivariate analysis of ischaemic heart disease mortality in B.C. Results indicate a strong association between heart disease outcomes and educational background for both males and females. Findings of this study support a link between IHD and psychosocial factors. The results of the multiple regression must be interpreted with caution, given the use of an ecologic analysis. Additional research at the individual level is needed to fully understand these relationships.

Adult↗