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Biomedical subjects

A De Schepper

Publications and source records attributed to A De Schepper.

At least 73 records · Page 4Linked to original sources
PubMed1992

Diagnostic imaging of muscular tumors.

Eight patients with muscular tumors--all malignant--were reviewed. Seven patients were examined by magnetic resonance imaging. Some of them also underwent conventional radiology and computed tomography. One patient was examined by computed tomography only. An overview and short description of the muscular tumors are given. The findings with the different imaging techniques are presented, followed by a discussion of the role of the imaging techniques. The final conclusion is that MRI is the modality of choice for detection, staging, and follow-up of muscular tumors, although the signal intensity features are not always specific.

Adult↗
PubMed1992

[Imaging of aortic dissection: a retrospective study of 27 patients].

Aortic dissection can be a life threatening condition which requires an early diagnosis. As initial signs and symptoms may be nonspecific and confusing, reliable imaging techniques are requested for immediate and accurate diagnosis. This retrospective study of 27 patients with proven aortic dissection assesses the relative value of angiography, CT, and MR imaging. Contribution of these imaging modalities is discussed and illustrated. Aortic dissection was correctly identified by angiography and CT respectively in 100% and 83% of the cases. MRI was diagnostic in all six examined cases. Both angiography and CT proved to be reliable imaging modalities; in addition, they can be easily performed in the critically ill patient. We consider MRI useful in the evaluation of suspected dissection in stable patients and follow-up of medical or surgical therapy.

Adult↗
PubMed1991

Computed tomography of the brain in unipolar depression.

Several authors have reported enlarged lateral brain ventricles in major depressive patients as compared to healthy controls. Also, the enlargement of brain lateral ventricles has been related to delusions, psychomotor retardation and some biochemical data such as cortisol secretion and L-tryptophan serum levels. The present study was undertaken to investigate if melancholic depressives are characterised by a higher degree of brain atrophy than normal controls and minor depressives, the origin of any brain atrophy, and whether measures of brain atrophy are related to cortisol secretion and L-tryptophan serum levels. We investigated 10 healthy controls and 35 depressive patients categorised according to DSM-III. In contrast to previous studies, we determined a combination of indices which makes it possible to differentiate between central and cortical diffuse atrophy. We found no evidence for the existence of abnormal atrophy of the brain in melancholics; nor did we find any correlation between CT scan measurements and cortisol or tryptophan.

Atrophy↗
PubMed1991

Computed tomography of major salivary gland tumors. A retrospective study of 31 cases.

To assess the value of computed tomography (CT) in grading (benign versus malignant) and characterization of salivary gland tumors we retrospectively analysed the CT examinations of 31 histologically proven cases (15 pleomorphic adenomas, 6 cystadenolymphomas, 1 lipoma, 4 malignant tumors, 4 cysts, and 1 abscess). Subsequently we studied the localization, size, shape, margins, intratumoral calcification, central lucency, local invasion, homogeneity, density, degree and pattern of enhancement after intravenous contrast injection, and presence of enlarged locoregional lymph nodes. A lesion with ill-defined margins, local invasion, diffuse spread throughout the gland and enlarged locoregional lymph nodes was considered malignant. All malignant lesions were correctly diagnosed (no false negative) but 3 benign lesions had malignant features on CT (3 false positives). Further characterization between pleomorphic adenomas and cystadenolymphomas is often impossible. A cystic lesion with papillary contrast-enhancing projections was found in 2 out of 6 cystadenolymphomas and not in other lesions.

Adenolymphoma↗
PubMed1991

Ultrasonography of the salivary glands in the evaluation of Sjögren's syndrome. Comparison with sialography.

Ultrasonography (US) was evaluated as noninvasive method to determine salivary gland involvement and compared with sialography in patients with Sjögren's syndrome (SS) and patients with only objective xerostomia and/or xerophthalmia. Patients with complaints of dry eyes and dry mouth but with no objective abnormalities served as control group. Ultrasound revealed a decreased parotid gland reflectivity in most of the patients with SS, compared with only 2 patients in the other group (p = 0.002). Our study suggests that US can be a useful, noninvasive method in the diagnostic work-up of patients with sicca complaints.

Humans↗
PubMed1991

Ultrasonographic diagnosis of chondromalacia of the femoropatellar joint.

In 35 patients suffering from femoropatellar arthralgia, ultrasound of the cartilage at the femoral side of the FP joint and double contrast computed arthrotomography were obtained. The criteria for chondromalacia in these examination techniques are discussed. In US the sharpness of the cartilage-bone interface and the relative reflectivity of the quadriceps tendon in comparison to the cartilage appeared to be relevant. US seemed to be a very specific technique in comparison with double contrast ARCT, but those patients with unique degeneration of the cartilage of the patella were missed with US (22%). Because US is a non-invasive, cheap and widely available procedure, we believe that US is a very useful screening procedure in the approach of the patient suspected of chondromalacia.

Adolescent↗
PubMed1990

Acromegaly, multinodular goiter and silent polyostotic fibrous dysplasia. A variant of the McCune-Albright syndrome.

A 36-year-old woman is reported with a possible variant of the McCune-Albright syndrome. The triad was incomplete because of the absence of skin pigmentation and since the sexual precocity was not evident. The presence of a pituitary mass and the secretory dynamics of growth hormone and prolactin were suggestive of a mammosomatotroph cell adenoma. A toxic multinodular goiter was also associated, but unique was the spontaneous normalization of the thyroid function. Unusual was the silent evolution of the polyostotic fibrous dysplasia, which was only fortuitously discovered during magnetic resonance imaging of the pituitary region. Treatment of the acromegaly with the long-acting somatostatin analogue octreotide resulted in an important inhibition of the GH secretion and in a reduction of the volume of the pituitary adenoma.

Acromegaly↗
PubMed1990

A pharyngeal hairy polyp causing neonatal airway obstruction: a case study.

A case of neonatal respiratory distress due to an oropharyngeal hairy polyp is reported with its MRI assessment. The place of hairy polyps in the differential diagnosis of upper respiratory tract obstruction is discussed. Early and rapid diagnosis and treatment may be lifesaving for the newborn.

Airway Obstruction↗
PubMed1990

[Esophageal perforation caused by a foreign body: a conservative approach].

The etiology, diagnosis and therapy of esophageal perforations due to foreign bodies are discussed on the basis of a case and a literature survey. Eighty percent of the esophageal perforations are iatrogenic. Pain is the first symptom. When appearing after manipulation of the esophagus, a perforation should be ruled out by means of radiology. This should be done by soft tissues radiography of the neck, barium study of the esophagus and chest radiography. The early prevention of contamination and administration of antibiotics are important conditions of a successful conservative therapy.

Anti-Bacterial Agents↗
PubMed1988

Palpable solid breast masses: retrospective single- and multimodality evaluation of 201 lesions.

The diagnostic virtues and limitations of single- and multimodality testing in the evaluation of solid palpable breast masses were studied. Two hundred one consecutive patients who had a solid palpable breast mass and who underwent biopsy between September 1982 and July 1986 were included for blinded retrospective analysis of their physical examination, mammographic, ultrasonographic (US), thermographic, and pathologic characteristics. Benign breast disease was diagnosed histologically in 106 women, while carcinoma was established in 95. The sensitivities of physical examination, mammography, US, and thermography were 0.88, 0.94, 0.78, and 0.49, respectively. US alone had the highest sensitivity in correct diagnosis of a benign solid breast mass and had the highest accuracy (0.84). Use of four modalities increased the preoperative diagnostic true-positive rate to 0.97, with some decline in specificity. Multimodality testing seems particularly beneficial in pre- and perimenopausal patients.

Adult↗