Ventilation was analysed during a maximal and progressive exercise in 12 patients suffering from interstitial lung disease (ILD) and in 15 healthy subjects. "Rapid shallowing breathing" pattern was observed in patients with ILD. Both normals and patients showed a linear relationship between VE, VT/TI (mean inspiratory flow) and VCO2. The relationship between P0.1, the occlusion pressure at 0.1 S, and VCO2 exponential in both groups and significantly steeper in patients with ILD. P0.1/VE and P0.1/(VT/TI) ratios, indexes of thoracopulmonary impedance, and P0.1/VCO2 ratio, an index of respiratory drive per unit of CO2 output, were all inversely correlated in patients with VC% (vital capacity) and CLstat (static compliance). These results strongly suggest that in patients suffering from ILD the higher respiratory drive observed during exercise could be attributed to increased afferent reflexes originating from the lung and/or chest wall.

Adult↗

PubMedDate not supplied

Pulmonary function in patients with primary spontaneous pneumothorax.

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Adolescent↗

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Follow-up of pulmonary function after "shock lung".

Long-term follow-up of pulmonary function has been performed in four patients having recovered from "shock lung". In three patients there is a progressive normalization of lung volumes and lung compliance, whereas the pulmonary diffusing capacity improves but without attaining predicted levels. In the fourth patient, a delayed reduction of total lung capacity, lung compliance and diffusion capacity occurred. During the follow-up period (from one month to four years) there was no complaint and physical examination, electrocardiogram, chest roentgenogram, conventional pulmonary perfusion scintigraphy and arterial blood gases at rest were quite normal. These results are compatible with the persistence of some degree of interstitial lung disease after recovery from "shock lung".

Adult↗

PubMedDate not supplied

[Therapeutic effects of physical training in patients with chronic respiratory insufficiency].

The therapeutic benefits of physical training for patients with chronic respiratory insufficiency must be assessed on the clinical, physiopathological and sociopsychological planes. As far as the clinical state is concerned, one observes a reduction of dyspnea and of the frequency of hospitalizations and an increase in the level of daily activity. On the physiopathological point of view, one observes an increase in the maximal capacity of exercise ranging from 1 to 33% resulting mostly from a better peripheral oxygen extraction. Pulmonary function is little modified on the spirographic level; however, one observes an improvement of blood gases at rest which seems to result from better alveolar ventilation. No systematic change in the circulatory variables is reported, except for a reduction of the PPA at rest. About the psychological factors, one observes a reduction of anxiety and an increase in motivation to perform muscular exercise. These results are difficult to obtain and often require a long rehabilitation. Socially, numerous obstacles are encountered to a social reinstatement : a relatively advanced age, a disadvantaged social environment, a low cultural level and an affectively weak surrounding. The solution to these different problems must be sought for each individual and the rehabilitation must be pursued continually; this often necessitates the hospitalization of the patient in a rehabilitation institute. On the basis of these studies, it seems certain that physical training is beneficial to patients with chronic respiratory insufficiency. However different programmes should be proposed for patients in an advanced or intial stage of their illness.

Chronic Disease↗