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Biomedical subjects

A Davignon

Publications and source records attributed to A Davignon.

At least 91 records · Page 5Linked to original sources

A new surgical approach for correction of partial anomalous pulmonary venous drainage into the superior vena cava.

Nine children with partial anomalous pulmonary venous drainage into the superior vena cava were operated upon. The technique consisted essentially of partitioning and enlargement of the superior vena cava. The partitioning was done in all but one patient, with a longitudinal suture starting above the highest pulmonary vein directing the pulmonary venous flow through the enlarged atrial septal defect into the left atrium. The anterior cavo-auricular tunnel was enlarged with a right atrial appendage-superior vena cava angioplasty. Follow-up studies were done between 1 and 3 years after surgery. The hemodynamic data were normal in 7 patients. In 8 children, the superior vena cava was unobstructed and its diameter was normal as demonstrated by cavograms. In all patients, the angiographic evaluation of the pulmonary venous return was normal. These results are encouraging and indicate that this new approach is superior to those which have previously been reported.

Angiography↗

Hemangiomatosis of the liver in infants.

Seven patients with hemangiomatosis of the liver are presented together with 100 cases reported in the literature. Six of seven patients survived; four with supportive treatment only. Follow-up is from 2 to 11 yr. Hepatomegaly, heart failure, and cutaneous angiomas constitute the classical clinical triad. Arteriography is the best method for diagnosis; biopsy should be avoided. Clinical features and histologic examination of these benign vascular tumors seem to confirm the theory that hemangioendothelioma and hemangioma represent only different developmental stages of one disease. These lesions can regress spontaneously if left alone. Despite contrary prevailing opinion, the authors recommend nonoperative treatment as the first choice of the clinician.

Age Factors↗

[Hemangiomatosis of the liver in infants: Diagnosis and treatment].

The authors present 7 patients with hemangiomatosis of the liver together with about 100 cases reported in the literature. 6 of 7 patients survived; 4 with supportive treatment only. Follow-up is from 2 to 12 years. Hepatomegaly, heart failure and cutaneous angiomas constitute the classical clinical triad. Arteriography is the best method to diagnose this lesion, and biopsy can thus be avoided. Clinical features and histological examination of these benign vascular tumors seem to confirm the theory that hemangioendothelioma and hemangioma represent only two different developmental stages of one disease. These lesions can regress spontaneously if left alone. Despite contrary prevailing opinion the conservative treatment is recommended as the first choice of the clinician.

Female↗

[Heart tumors in children. Report of 3 cases with favorable spontaneous courses].

During a 14-year period, 8 cases of primary heart tumours were observed at Sainte-Justine Hospital. Three of these patients had a favourable course without any surgical treatment. The age of these patients was respectively 3 days, 7 weeks and 6 1/2 years. In what concerns the first two patients, the clinical and paraclinical pictures were suggestive of heart disease from the onset. Catheterization and angiocardiography confirmed the presence of a tumour deforming both ventricular cavities. In these two cases, an attempt at surgical resection proved to be impossible in view of the extent of the lesion. Biopsy demonstrated a rhabdomyoma in one of the patients and a diffuse fibroma in the other. Six and four years later, the patients were still alive, and an improvement of both the electrocardiogram and of the cardio-pulmonary X-ray pictures were noted. A second cardiac catheterization showed an almost complete disappearance of the pathological pictures. In what concerns the third patient, he was a 6-year old child with a classical Bourneville's tuberous sclerosis with a localized tumour at the junction of the superior vena cava and the right atrium. Three years later a control catheterization showed the tumour to have remained unchanged. Two conclusions might be drawn from these cases: 1 a surgical operation, although always indicated, should never entail a desperate attempt at tumour removal; 2 the prognosis should never be considered as lethal from the start.

Child, Preschool↗

[Abnormalities of the aortic arch. Apropos of 30 surgical cases in children].

Few large surgical series have till now been devoted to aortic arch anomalies. Thirty cases operated upon in 10 years at the Hôpital Sainte-Justine are studied in the present work; they include: 8 cases of double-arch, 21 of aberrant subclavian arteries and 1 of aberrant brachio-cephalic trunk. In this apparently very complex embryological domain, a simplified classification, easy to remember even by the non-specialist, might be applied. There are no clinically significant differences between the various anatomical anomalies considered, the latter showing generally, soon after birth, by respiratory manifestations. The frequently severe spontaneous course requires an early diagnosis which relies on a simple procedure: the oesophagogram. A quick surgical treatment is then indicated, and the majority of our patients were operated upon in the early months of life. No post-operative death was observed and the long-term course might be considered as excellent in all the cases in which the malformation was alone and corrected early.

Aorta↗

Mechanography: a non-invasive technique for the evaluation of cardiac function in children.

Experience in the pediatric age group with mechanography, an indirect method of cardiovascular investigation, is described with emphasis on the recording technique and on the analysis of the tracings. A few examples are presented with comments on the morphological aspects and the time characteristics of the pulse curves, showing how much information about cardiac disease and especially myocardial function in children may be obtained.

Adolescent↗

Congenital aortic stenosis: follow-up of surgical management.

We have reviewed the cases operated upon for correction of congenital aortic stenosis at l'Hôpital Ste-Justine between 1959 and 1969.Twenty-five of the 26 patients were readmitted for complete clinical, radiological and hemodynamic investigation. Fourteen had a valvular stenosis, eight a diaphragmatic subvalvular lesion, and three had mixed lesions.The results lead us to believe that the surgical treatment of this malformation is justified. The indications for surgery must take into account all available clinical, radiological, electrocardiographic and hemodynamic data.

Adolescent↗