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A Date

Publications and source records attributed to A Date.

At least 73 records · Page 4Linked to original sources
PubMed1983

Renal lesions in the obliterative cardiomyopathies: endomyocardial fibrosis and Loffler's endocarditis.

Electron and, or light microscopic examination of paraffin embedded renal tissue obtained from necropsies on eleven patients with obliterative cardiomyopathy showed a variety of abnormalities. Glomerular lesions present in patients with endomyocardial fibrosis included capillary wall thickening, basement membrane duplication, mesangial expansion and interposition, intraluminal fibrin and dense subendothelial deposits. These changes, some of which have been reported earlier in patients with Loffler's endocarditis, probably result from deposition and organisation of immune complexes.

Adolescent↗
PubMed1983

Filarial chyluria with opportunistic infections.

A patient with long-standing filarial chyluria developed severe lymphocytopenia, extensive mucosal candidiasis and disseminated cryptococcosis when given small doses of prednisolone and azathioprine, for the treatment of a co-existing chronic active hepatitis. This report suggests that patients with chyluria are particularly susceptible to the complications of immunosuppressive therapy. This susceptibility is probably due to the immunological abnormalities associated with chyluria.

Azathioprine↗
PubMed1983

Membranoproliferative glomerulonephritis in a tropical environment.

Electron microscopy of renal biopsy material from 50 patients with membranoproliferative glomerulonephritis treated in a southern Indian hospital, showed a low prevalence of type 2 (dense deposit) disease. Eosinophilia was seen in more than one-third of the 41 patients with type 1 disease. Associated diseases and possible sources of chronic antigenaemia found in some patients included: streptococcal infection, Bancroftian filariasis, tropical pulmonary eosinophilia, hepatitis B surface antigenaemia and lepromatous leprosy.

Adolescent↗
PubMed1983

Epstein-Barr virus-associated Burkitt's lymphoma in India.

We studied two cases of Burkitt's lymphoma (BL) recently seen at out institution for association with the Epstein-Barr (EB) virus. Biopsies from both patients fulfilled the established criteria for the diagnosis of BL. One case had clinical features resembling those of EB virus-associated BL, and showed a pattern of elevated titres of antibodies to EB viral antigens indicative of virus association. The second case had several clinical features resembling those of non-virus-associated BL, and did not show the diagnostic serologic pattern. This report documents for the first time the association of EB virus with BL in India, and indicates that the virus-associated and non-virus-associated forms of BL may coexist in this country.

Antibodies, Viral↗
PubMed1982

Renal ultrastructure in acute tubular necrosis following Russell's viper envenomation.

Electron microscopic examination of renal biopsies from nine patients who developed renal failure after Russell's viper bite showed glomerular mesangial hypercellularity, vascular endothelial swelling, tubular epithelial necrosis and shedding, acellular segments of tubular basement membrane and an interstitial infiltrate composed of mast cells, eosinophils, lymphocytes and plasma cells. These cells showed many close contacts with each other and with fibroblasts. Severe vascular and tubular lesions were also present in the medulla. These abnormalities and other reported clinical and laboratory investigations in this condition, suggest that the primary lesion is a reversible intravascular coagulation with secondary ischaemic tubular damage. The inflammatory response in the interstitium is probably initiated by a release of antigens from damaged tubules.

Acute Kidney Injury↗
PubMed1982

Outcome of the haemolytic-uraemic syndrome complicating bacillary dysentery.

Seventy-eight children were treated for the haemolytic-uraemic syndrome complicating bacillary dysentery over a ten-year period. Early dialysis favoured survival significantly. The renal status of 22 of the 28 survivors was re-evaluated 18-84 months after initial hospitalization. Complete recovery was found in all except two patients; one of them had neurological sequelae and the other a glomerulonephritic disease.

Child↗
PubMed1982

Thioflavin T fluorescence in membranoproliferative glomerulonephritis.

Paraffin-embedded renal biopsy material from 50 cases of membranoproliferative glomerulonephritis (MPGN) was studied by thioflavin T staining and electron microscopy. Glomerular capillaries showed bright diffuse linear thioflavin T fluorescence in all cases of MPGN type 2 and also in some cases of MPGN types 1 and 3. This pattern of fluorescence appears to be related to the extent of intraglomerular deposits, rather than their location or nature.

Benzothiazoles↗
PubMed1982

Terminal infections in renal transplant patients in a tropical environment.

Infections were a major cause of death in 84% of 38 autopsied renal allograft recipients in a south Indian hospital. Pyogenic bacteria and fungi were the most common etiological agents encountered, being present in 50 and 47% of cases, respectively. Tuberculosis and hepatitis B virus infection were more prevalent and Pneumocystis carinii and cytomegalovirus disease rarer than in comparable series from non-tropical countries. 1 case each of amoebiasis, strongyloidiasis and filariasis were the parasitic infections encountered.

Adult↗
PubMed1982

Renal transplantation in leprosy.

A patient with tuberculoid leprosy and chronic renal failure was given a renal allograft after 5 months of dapsone (DDS) treatment. The leprosy showed continued healing in spite of immunosuppression and was not a significant cause of morbidity. Tuberculoid leprosy does not appear to be a contraindication for renal transplantation.

Adult↗
PubMed1981

Nephron injury in the haemolytic-uraemic syndrome complicating bacillary dysentery.

The electron microscopic appearances of renal biopsy material from four children who developed the haemolytic-uraemic syndrome as a complication of bacillary dysentery are described. Glomerular lesions present included deposits of fibrin and platelets, subendothelial rarefaction and lysis of endocapillary cells with or without necrosis of glomerular epithelial cells and periglomerular tissue. Tubular epithelial necrosis and cytoplasmic degeneration with an infiltrate of lymphocytes and plasma cells were also seen. It is likely that the different glomerular lesions result from thrombosis and obstruction of blood vessels at various levels of the intrarenal circulation. The tubulo-interstitial changes appear to be secondary to glomerular lesions.

Child, Preschool↗
PubMed1981

Acute renal failure in children following snake bite.

Snake venom poisoning accounted for 1.4% of 4360 infants and children admitted to a south Indian hospital during the years 1976-1979 and was the commonest cause of acute renal failure encountered. Most of the 42 children with anuria following snake bite had evidence of intravascular coagulation and acute tubular necrosis. Russell's viper was the only snake recognized in all the cases of anuria in which species identification was possible. Renal failure complicating snake bite was relatively more frequent and more severe in children than in adults.

Acute Kidney Injury↗