The Basle longitudinal study: report on the relation of initial glucose level to baseline ECG abnormalities, peripheral artery disease, and subsequent mortality.
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Biomedical subjects
Publications and source records attributed to A Da Silva.
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Currently, many countries throughout the world are reforming their health services. Even though these reforms differ according to the country's characteristics, they share many policies, one of which is the promotion of social participation in health-related matters. This policy, however, is not new in the field of health service organization. Throughout the last century, individual or collective collaboration between the population and health services has been promoted by several philosophies and concepts with different aims: from the search for collaboration with the general public to broaden public health system coverage to the promotion of the creation of mechanisms that would allow society to exercise control over these services' performance. Nevertheless, for the public to be involved with these services, several factors concerning both the services themselves and the population, need to converge. Although the theoretical frameworks that have encouraged social participation throughout the history of the development of health systems differ considerably, their practical implementation shares many common elements in all periods, from participation as a means of obtaining certain objectives to being an end in itself, as a democratic process. This can also be applied to the current promotion of social participation policies in the context of health care reforms, which are analyzed using Colombia and Brazil as examples.
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The study is based on the data's of general practitioners of some Health Communities in Portugal in 1991. On 4,247 patients 1.5 p. cent consulted for venous disease, half of them with severe chronic venous insufficiency. The patients with ulcers needed an average of 32 dressings. Mean disability lasted 38.7 days and 12.5 of the patients took early retirement. The social cost of the disease is set out in this study. The author concludes that prophylactic measures should be taken at the working place.
In order to see whether thrombolytic therapy led to a reduction of CPT, a cause of long periods of inability to work, a study on the development of phlebothrombosis was carried out at the Department of Angiology at the Hospital Cantonal of Basle. Subjects presenting deep phlebothrombosis, either acute or sub-acute, were observed after 5 years... Or the 341 patients, 208 received streptokinase and 133 heparin. After the 5 years, 1 in 5 patients had developed CPT. The incidence of CPT was above all related to the extent of the thrombosis. If one considers not only the immediate therapeutic effect but also the extent of the thrombosis, then the incidence of CPT, especially in leg ulcers, is roughly twice as high in patients with extensive thromboses, and therapy is negative, as in the patients with thromboses limited to two stages only, in which group the therapy is positive. It has even been eliminated where the thrombosis had been limited to the leg. Prophylactic measures are therefore necessary in the groups at high risk. The diagnosis must be swift in order to commence correct therapy whilst the thrombosis is not as yet extensive. Heparin therapy seems to be enough for those thromboses limited to the leg. Whilst awaiting thrombolytic methods without serious side-effects, thrombolytic treatment should be reserved for extensive thromboses in young patients with no contraindications. It is a condition sine qua non that the patient and the parameters of coagulation should be monitored.
There is little agreement on the real prevalence and significance of varices of the lower limbs. The discrepancies between the data produced by the various studies are attributable to several factors, of which the most important has to be the absence of any definition of the forms and types of varices. In the Basle study there has been an attempt to classify into two groups, "disorder" and "disease", according to the severity of the clinical picture. These two groups are clearly distinct regarding complications and the number of risk factors. A study on the long-term development has also shown that at the end of 11 years the group "disease" more frequently presented socio-medical after-effects than the group "disorder". Pronounced varices therefore do constitute a real disease and merit appropriate attention.
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