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Biomedical subjects

A D Weaver

Publications and source records attributed to A D Weaver.

At least 37 records · Page 2Linked to original sources

Demographic studies on final year veterinary students of nine European schools.

In 1975 a survey of some aspects of veterinary student selection, background and education as well as intended employment after qualification was conducted in the veterinary schools at Bristol, Glasgow, Liverpool, Helsinki, Stockholm, Hannover, Ghent, Toulouse and Vienna. In all schools student selection was primarily based on academic ability. A numerus clausus existed in six of the nine schools. No sex discrimination in student selection was practised in seven of the nine schools. The proportion of male students in the final year of 1975 ranged from 57 per cent in Glasgow to 97 per cent in Ghent. The parents of the students were predominantly of socioeconomic classes 1 (28 per cent), 2 (38 per cent) or 3 non manual (20 per cent), and no significant differences were found between the UK and the continental schools. Six per cent of the parents were veterinarians while 15 per cent were farmers. The financing by students of their veterinary studies varied markedly between schools. Over 80 per cent of the students wished to go first into general practice, with little tendency, except among UK students, to go into employment abroad first.

Adult↗

Phenotypic intersex (female pseudohermaphroditism) in a dachshund dog.

A male miniature rough-haired dachshund, presented with episodic haematuria, was found to be a female pseudohermaphrodite. A littermate also had an abnormality of the urogenital tract and their dam had received a progesterone implant during pregnancy. Chromosome analysis of the intersex revealed XX/XY mosaicism in certain tissues.

Animals↗

Discrete prostatic (paraprostatic) cysts in the dog.

A description is given of the history, clinical features, surgery, outcome and pathology of 12 dogs with discrete prostatic cysts over 50 ml in volume. The dogs were middle-aged and presented with either urinary or alimentary signs or both. The cyst was usually palpable in the posterior abdomen as a smooth, non-painful mass, readily demonstrable on contrast radiography (pneumocystogram). Attempts were made to drain and resect the cysts, but resection often proved difficult due to its attachment to the region of bladder neck and ureters. In no case could the origin be shown to be from an enlarged uterus masculinus. The cyst content was invariably sterile, but its nature and the pathology of the cyst wall varied considerably between individuals. Since the long-term outcome was only satisfactory in three cases, the prognosis must be guarded.

Animals↗

Hip dysplasia in beef cattle.

A bilateral hip lameness has been found in young beef bulls of the Hereford, Aberdeen Angus, Galloway and Charolais breeds in the United Kingdom, North America and Australia. The incidence is usually small and sporadic, but up to half of the male animals on one farm may be affected clinically by the time they are one year old. Clinical lameness begins at three months to two years old, and very occasionally up to three years of age; some calves are obviously affected at birth. Aberdeen Angus cattle tend to be affected earlier than other breeds. Clinical evidence of the condition is almost entirely confined to the male.

Animals↗

The relative effectiveness of some chelating agents as antidotes in acute cadmium poisoning.

An examination has been made of the relative effectiveness of three chelating agents in reducing lethality in acute cadmium poisoning. The chelating agents used were sodium 2,3 dimercaptosulfonate (DMPS), N-Acetyl d,1 penicillamine (NAPA), and 2,3 dimercaptosuccinic acid (DMSA). For cadmium acetate administered ip at a level of 16.9 mg/kg, the oral administration of the chelating agents at a 20:1 mole ratio in three doses subsequent to the cadmium acetate at 20 minutes, 90 minutes, and 210 minutes resulted in a significant enhancement of the survival rate for all three compounds. At this level none of the control animals survived beyond 2 days. On the basis of the experiments carried out here the survival rates decreased in the order sodium 2,3 dimercaptopropane-sulfonate greater than 2,3 dimercaptosuccinic acid greater than N-Acetyl d,l penicillamine. In a study of the effect of the mole ratio of the chelating agent sodium 2,3 dimercaptopropanesulfonate to cadmium acetate on the survival rate, it was found that the survival rate attained a maximum for values between 20 and 60 and dropped off at both higher and lower values. It was also found that for at least one set of conditions, younger animals were better able to survive the administration of cadmium acetate and the antidote than older animals.

Animals↗

Lidocaine concentrations associated with intravenous regional anesthesia of the distal limb of cattle.

Cannulation for injection of lidocaine HCl was done in 3 distal veins in the hindlimb of 5 young Friesian cattle maintained in a light plane of general anesthesia. The local and systemic plasma and tibiotarsal joint synovial fluid concentrations of lidocaine (British lignocaine) were estimated for 60 minutes after the drug (10 ml, 2% (w/v)) was injected into the veins distal to a tourniquet. The lidocaine concentration in the distal veins was high but variable initially, and fell markedly over the 60 minutes. The systemic circulation always had a low but measurable concentration of lidocaine that became slightly higher in the 5 minutes after tourniquet release. According to the concentrations found, the risk of toxicity of lidocaine by using this technique in clinical practice would appear negligible.

Anesthesia, Conduction↗

Lower urinary tract pathogens in the dog and their sensitivity to chemotherapeutic agents.

Ninety-six urine samples were collected by a sterile technique from 75 dogs affected with urinary tract disease (cystitis, urolithiasis, prostatitis, etc) involving bacteruria. The infecting organisms were isolated and tested against sensitivity discs (penicillin G, streptomycin, chloramphenicol, tetracycline, sulphamethoxazole/trimethaprin and Sulphatriad). The commonest isolate was Escherichia coli, which was generally sensitive to several agents, though in eight cases it was resistant to all drugs. Next in order were Streptococcus faecalis, Staphylococcus epidermidis and Proteus spp. A double infection was present in 11 cases. Further data give a breakdown for sex and the clinical diagnosis, neither of which was related to any particular organism.

Animals↗

Slaughterhouse condemnations for hind leg disease in cattle.

Hindlimb condemnations occurred in 0-11 per cent (194/173,580) of all cattle at a large Scottish slaughterhouse over a 22-month period. Cows and bulls were more frequently involved than steers or heifers. Gross pathology, studied in 42 cattle (21 per cent of the total condemned), revealed osteoarthritis of the stifle and hip respectively in 19 and 16 cases. The traumatic lesions included meniscal damage, anterior and other ligamentous rupture. The UK loss from such condemnation is estimated at over pounds200,000 in January 1977.

Abattoirs↗

Relationship of bacterial infection in urine and calculi to canine urolithiasis.

In 26 dogs treated surgically for urolithiasis, bacteriological examination of the urine and the interior of calculi showed that infection was present in both materials in 14 cases. Infection with phosphate calculi, present in 13 of these 14 dogs, was associated with a variety of bacteria including Staphylococcus aureus, Staph epidermidis, Streptococcus faecalis, Escherichia coli and Proteus spp. In a follow-up examination of 16 dogs, organisms different from the original isolates were recovered from some cases. The significance of the persistence of viable bacteria within canine bladder calculi is discussed.

Animals↗