Biomedical subjects
Publications and source records attributed to A D Slonim.
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The long-term (45 days) acclimation of the Mongolian gerbil, in contrast to albino rats, is not accompanied by adaptive changes in general metabolism, chemical thermoregulation, bioelectric skeletal muscles activity, and tissue respiration in muscles and liver. The effect of short-term intermittent cooling in the Mongolian gerbil is of short duration and does not manifest itself in increased stability of body temperature. The calorigenic effect of norepinephrine may be only observed after a long-term adaptation. The pattern of adaptation to cold in the Mongolian gerbil, a typical habitant of continental climate of Central Asia, depends on the stability of its normal thermoregulation.
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In estimating, by use of cosinor-test, the 12- and 24-h component parameters of body temperature circadian rhythm in monkeys under ultradian schedules of lighting and feeding (LD 6:6; DL 6:6) we have shown that an intensive 12-h component is registered in both cases. The presence of a 24-h component of circadian rhythm depends on the zeitgeber phase. This component is present in LD 6:6 (lighting hours 07:00-13:00 and 19:00-01:00) and is absent in DL 6:6 (01:00-07:00 and 13:00-19:00). We hold that the most satisfactory explanation of the phenomena observed is that 12-h component is the result of a masking effect induced by the 12-h schedule (exogenous component) whereas the 24-h component reflects the intrinsic pacemaker work (endogenous component). It should be noted that in our case the masking effect in body temperature rhythm is circadian phase-dependent.
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