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Biomedical subjects

A D Rapidis

Publications and source records attributed to A D Rapidis.

At least 37 records · Page 2Linked to original sources
PubMed1982

Median cysts of the jaws--not a true clinical entity.

The so-called median cysts of the jaws (median mandibular and median palatine) are currently classified as fissural cysts. Their existence as distinct clinical and histological entities has been the cause of debate. It is the purpose of this paper to point out that from present evidence in published case reports and reviews of the literature, the presence of these cysts in the midline of the jaws is a random finding. It is suggested that the title median mandibular and median palatine cysts should be discontinued and that cysts at these sites should be labelled according to their particular histopathology.

Humans↗
PubMed1981

Frey's syndrome.

Explore the source record for details and available documents.

Adolescent↗
PubMed1980

The team approach in the management of oral cancer.

The management of cancer of the head and neck is so complex that it demands the participation of two teams, one major or curative and the other minor or supportive, and also of the patient. The make-up of these teams and the functions of their members are discussed. The principles of treatment planning along these lines are outlined and the importance of close interdisciplinary collaboration is emphasised.

Head and Neck Neoplasms↗
PubMed1979

Histiocytosis X: current concepts and a report of two cases.

The current concepts of histiocytosis X are discussed, and the literature concering this rare disease of obscure aetiology reviewed. Two case reports of histiocytosis X presenting in similar sites in young children of similar ages, but with markedly different courses, are presented. The importance of early recognition of the disease, particularly by the dental surgeon who may see the first oral signs, is stressed. Attention is drawn to the danger of misdiagnosing the oral signs of histiocytosis X, particularly as periodontal disease. The possible aetiologies are examined and current treatment regimes discussed.

Child, Preschool↗
PubMed1979

Oral cancer and sex, Why do females do better?

Analysis of a group of 194 patients with squamous cell carcinoma of the oral cavity has shown that the survival figures for females is significantly better than that for males. The material has been analyzed in an attempt to explain this difference. The females in this series did not attend at an earlier stage, at a younger age or with more highly differentiated tumours. The site distribution was similar for the two sexes but the improved survival for females was found particularly with tumours of the cheek and commissure region and the lower alveolus. Various possible explanations are discussed and it is suggested that the host response of females to intra-oral cancer is different to that of males.

Adolescent↗
PubMed1978

Histiocytosis X. An analysis of 50 cases.

Evidence is presented to support the author's view that Letter-Siwe disease, Hand-Schüller-Christian disease and eosinophilic granuloma are but variants of a single disease entity--histiocytosis X. The clinical behaviour of the disease and its prognosis are related to the age ofonset of the disease. Details of 50 cases of histiocytosis X have been analyzed. The mean age of presentation was 15 years 4 months. The male:female ratio was 3:2, 54% of patients in this series had disease confined to the jaws and oral cavity, males being more likely than females to have disseminated disease.

Adolescent↗
PubMed1978

The importance of accurate records and follow-up in patients with oral cancer.

A standardized patient record sheet is proposed to be used for all patients diagnosed as having oral squamous cell cancer. Such records would ensure thorough data recording and whilst providing accurate and complete information for retrospective and prospective analysis and research would also improve the follow up of such patients.

Dental Records↗
PubMed1977

STNMP: a new system for the clinico-pathological classification and identification of intra-oral carcinomata.

A new system for the notation of intra-oral carcinomata has been described. It differs from all previous TNM classifications in that both the site (S) and the pathology (P) have been taken into consideration in addition to the conventional tumour (T), node (N) and metastasis (M) generally used. Both of these additional features have been recognized as important factors in assessing the prognosis of the patient. This new system additionally functions as a means of disseminating the maximum of clinical information succinctly and in a readily communicable format. A further innovation has been the introduction of a means of quantitatively assessing the significance of particular clinical and pathological features and from these values predicting the prognosis. For comparative purposes we have defined four stages corresponding with the stages used in the conventional TNM classification. We have applied the STNMP classification to a random sample of 136 cases of intra-oral carcinomata with more than 5 years follow-up. Particularly in defining those patients with a good prognosis, i.e. 5 year plus survival, this system has proved to be considerably more accurate than the existing staging methods. We propose that for a trial period this system should be widely used in parallel with the conventional TNM classification and staging in order to evaluate its true worth in the clinical situation. With further use it will probably be necessary to adjust the numerical weighting given to particular features, but this can only be accurately assessed when a very large number of patients has been evaluated. Our figures support the clinical impression that patients with poorly differentiated squamous cell carcinomata have a shorter survival than those with well differentiated lesions and that the degree of differentiation of the tumour is directly proportional to the survival of the patient. When considering the site of the tumour we have based our grading on the known survival curves for squamous cell carcinomata at different sites.

Alveolar Process↗
PubMed1977

Oral cancer: the behaviour and response to treatment of 194 cases.

During the 16 year period 1960-1975, 350 cases of Oral Cancer were seen in the Department of Oral and Maxillo-Facial Surgery at the London Hospital. Detailed records were available for 250 patients. After excluding tumours of the salivary glands, sarcomata and tumours of the reticulo-endothelial system 194 cases remained and these were subjected to a computer analysis. The overall 5 year survival figure, not corrected for age and sex was, 32.8%. The local recurrence rate for all sites was 44%, 90% of these recurred within 2 years of diagnosis. The overall uncorrected 5 year survival figure for females was 42.1% and that for males was 22.9%. Analysis of the material has not provided a satisfactory explanation for this; lesions do not present at an earlier stage in females neither do they occur in younger patients. The distribution of the lesions by site and histology was the same for both sexes. Survival rates analysed by clinical staging at presentation confirm that the prognosis for early stage lesions is very much better than for late stage lesions, the 5 year survival for Stage I being 50% whereas that for Stage IV is only 20%.

Adolescent↗
PubMed1976

The therapeutic result of excision of the superficial temporal artery in atypical migraine.

A short review of the biochemical and clinical concepts of migraine and the different therapeutic approaches as well as the surgical procedure for the treatment of migraine is followed by the description of the treatment of eight patients suffering from atypical migraine. The selection of patients for this operation is limited to those cases suffering from classic migraine with the migraine attacks occurring in one and always the same side of the face and head. A step by step account of the procedure for the excision of a part of the super-zygomatic part of the superficial temporal artery is given with the results and the four year follow-up. In selected cases of atypical migraine, the above simple operation, may be curative.

Adult↗
PubMed1976

Ossifying Fibroma-one disease or six? An analysis of 39 fibro-osseous lesions of the jaws.

Thirty-nine cases of benign fibro-osseous lesions of the jaws of which ten cases were reported as central ossifying fibromata are reviewed. Such lesions usually present in young adults with the exception of classical fibrous dysplasia which is normally first diagnosed in the second decade of life. All the lesions appear to be more common in females and with the exception of the peripheral ossifying fibroma show a prediliction for the mandible. It is argued that as there is no absolute histological distinction between bone and cementum and as cementum-like areas of calcification are seen in fibro-osseous lesions of all membrane bones the distinction between ossifying and cementifying lesions should be discontinued. It is also suggested that the benign fibro-osseous jaw lesions may represent different stages in the evolution of a single disease process.

Adult↗