Obesity and cardiovascular risk factors in rheumatoid arthritis.
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Biomedical subjects
Publications and source records attributed to A D Quinn.
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1. The thermal environment experienced by broilers during transport and a 4 h lairage period were recorded for 8 loads of birds to 2 processing plants under summer and winter conditions. 2. During the transport period the thermal environment was considered not to have been a significant challenge to bird welfare. 3. During the lairage period, over all 8 d, external ambient temperatures were in the range 4 degrees to 15 degrees C during the winter trials and 12 degrees to 29 degrees C during the summer. Temperatures amongst the crated birds for this period were in the range 16 degrees to 29 degrees C and 20 degrees to 31 degrees C during the winter and summer trials respectively. 4. Air velocity measurements at bird level indicated air movement was of small magnitude (typically < 0.1 m/s) and of variable direction, despite the large air movements around the modules with speeds of over 1 m/s. 5. The potentially stressful thermal environments observed during lairage were achieved rapidly (< 1 h) after unloading. It is considered, therefore, that the minimisation of holding time alone is not a suitable control strategy. 6. The use of water-misting sprays as a control strategy in one lairage was observed to lower the temperature throughout the lairage but raised the humidity, which might offset the temperature advantage to the birds' thermoregulatory ability. 7. More closely controlled environments for broiler lairage facilities are suggested, with further work to increase air movement at bird level.
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The outcome of teaching the core of knowledge to clinicians and the impact of the POPUMET regulations was assessed using an anonymous questionnaire. 82 of 120 (76%) of non-radiologists responded, of these 37% had attended a radiation protection course. Course attendance improved knowledge of the existence of the POPUMET regulations (p < 0.0001) and the ALARA principle. Course attendance made no difference to knowledge of the relative radiation dose of various radiological procedures. An underestimation of radiation dose was made by all responders (p < 0.001). The majority of responders were not aware that patients have no annual dose limit and the majority did not know the relative radiosensitivity of different organs. We have shown that despite the POPUMET regulations the majority of clinicians have not received adequate radiation protection teaching and that even if a course has been attended overall knowledge is still poor. We propose that formal compulsory teaching at undergraduate level may correct this in the future.
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Under standard conditions double contrast barium enema (DCBE) was carried out on a selected patient cohort using either standard (1.5 mA) or low (0.5 mA) fluoroscopic current. A statistically significant (p < or = 0.01) reduction in total dose was achieved by use of low screening current. This reduction was of the order of 40%. Fluoroscopic image quality was analysed both objectively and subjectively, and was found not to be significantly degraded when the lower current was used. On blinded evaluation all examinations were found to be of diagnostic quality. The use of low fluoroscopic current results in a reduction in patient dose, without compromising fluoroscopic image quality or diagnostic standard of the examination. Low fluoroscopic current technique has been adopted as the standard in our department.
Acute mesenteric ischemia is a potentially life-threatening vascular disorder affecting the gastrointestinal tract. The prognosis depends on early recognition, accurate diagnosis, and timely intervention to prevent extensive tissue necrosis and the onset of sepsis and multi-organ complications. Identifying the patient at risk, evaluating physical findings and laboratory data, maintaining adequate cardiac output and perfusion pressure, and implementing medical interventions are nursing care measures essential to patient survival. Future directions for the management of acute mesenteric ischemia are focused on identifying early markers of ischemia and mucosal injury to diagnose the condition accurately and reliably before the onset of systemic consequences.
An asymptomatic nineteen-year-old white man presented with a markedly enlarged and indurated prostate. Urologic evaluation including cystoscopy, prostatic ultrasound, pelvic computerized tomography (CT) scan, and pelvic nuclear magnetic resonance imaging revealed a prostatic mass impinging on the bladder. Transrectal biopsies returned the pathologic diagnosis of rhabdomyomatous hamartoma. We report the first case in the English literature of extracardiac rhabdomyoma found in the male genitourinary tract.
We report on a patient with systemic sarcoidosis who presented with a lesion of the genitourinary tract confined to the testicle. Clinically evident sarcoidosis of the testicle has been identified in few instances. Several recommendations in evaluating such lesions have been offered. A consensus on treatment is not yet defined. The therapeutic options are presented and the literature is reviewed.
We present an unusual case of proximal extrusion of a semirigid penile prosthesis into the gluteal subcutaneous tissue. The possible causes, prevention, and treatment options of this uncommon complication are discussed.
Hydronephrosis of pregnancy is a common phenomenon that rarely requires invasive intervention. We describe a young woman with markedly obstructive hydronephrosis of pregnancy causing forniceal extravasation who was treated successfully by percutaneous nephrostomy. The rationale of such intervention and its advantages over retrograde ureteral catheterization or stenting are discussed.
Postoperative urinary retention is a common problem after surgery. Prevention includes obtaining a preoperative history and physical, having the patient void just before surgery, avoiding overhydration, and encouraging micturition soon after surgery. Management requires sterile catheterization, when indicated, to drain the urinary bladder completely. Urine cultures must be done when indwelling catheters are used. Antibiotics may be necessary.
Idiopathic segmental infarction of the greater omentum seldom enters into the differential diagnosis of acute abdominal pain, and diagnosis is usually not made until laparotomy. A preoperative clue to the diagnosis may be the lack of systemic gastrointestinal symptoms in the presence of impressive abdominal findings. Intraoperative clues are serosanguineous peritoneal fluid but normal appendix, distal small bowel, and mesentery. In this setting, careful examination of the omentum through the initial incision is recommended. Once identified, the infarcted omentum should be completely excised to prevent formation of adhesions and possible sepsis. In the case reported here, the serendipitous discovery of edematous omentum prompted a thorough--but technically difficult--exploration of the greater omentum, which eventually led to the correct diagnosis.
OBJECTIVE: The purpose of this study was to demonstrate that gadolinium-diethylenetriamine pentaacetic acid (Gd-DTPA) could be used as a contrast medium in CT as an alternative to iodine-based compounds. MATERIALS AND METHODS: Solutions of different concentrations of Gd-DTPA and iopromide were scanned in a tissue equivalent phantom and it was shown that Gd-DTPA caused 2.5 times the attenuation of an equimolar solution of iopromide. From these in vitro studies an in vivo dose of 0.5 mmol/kg Gd-DTPA was calculated to be equivalent to 50 ml iopromide 300. RESULTS: Pre- and postenhancement CT was performed in a volunteer using Gd-DTPA intravenously, and adequate enhancement occurred in intracranial vessels. CONCLUSION: Gd-DTPA can be used to provide enhancement during CT and might be of value in iodine-sensitive patients.