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Biomedical subjects

A D Osborne

Publications and source records attributed to A D Osborne.

At least 37 records · Page 2Linked to original sources
PubMed1975

Exposure to Br abortus in veterinary undergraduates and graduates.

Serial Brucella agglutination tests were carried out on veterinary students at Bristol University between 1962 and 1968. A steady rise in the number of those with a significant positive titre was demonstrated in undergraduates and this was related to an increased exposure to farm livestock as their course progressed. A much larger proportion of individuals showed a significant titre in the period following graduation. While only 8-9 per cent of students in the first year of their course showed a significant titre, 49-5 per cent gave a serological response at 1/80 dilution or greater, within five years ofgraduation and of those in predominantly large animal practice almost 60 per cent showed this response. Only 7 per cent of those with a significant rise in titre reported symptoms suggestive of clinical disease.

Antibodies, Bacterial↗
PubMed1974

Experimental Salmonella infection in calves. 1. The effect of stress factors on the carrier state.

Four calves were infected with 2.4 x 10(8)S. dublin and penned separately. Fluctuations in environmental temperature did not affect the symptoms of the disease or the duration of excretion. Faecal samples were superior to rectal swabs for detecting excretors.After transport stress, Salmonella was isolated from several organs at slaughter in an excreting calf, and uninoculated control calves became cross-infected. During slaughter, carcasses became contaminated on their surfaces. From one contaminated carcass Salmonella was recovered after chilled storage at 0 degrees C. for 1 week and also after freezing at -20 degrees C. for 1 month.

Abomasum↗
PubMed1974

Experimental Salmonella infection in calves. 2. Virulence and the spread of infection.

Calves with a serum ;H' titre of 1/160 developed a chronic form of salmonellosis after infection with S. dublin. Their growth rate was severely retarded by this illness. An aerogenic strain of S. dublin was found to be much more virulent than an anaerogenic strain. Faecal samples were superior to mouth swabs in detecting animals carrying S. dublin.During transport two uninoculated calves became infected and after transport stress, latent carriers of S. dublin with faecal samples negative for Salmonella for 5 weeks, restarted excretion. At slaughter Salmonella were isolated from viscera and organs and from the surface of five of six carcasses.

Animals↗