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Biomedical subjects

A D Hodgkiss

Publications and source records attributed to A D Hodgkiss.

7 recordsLinked to original sources
PubMed1995

Outcome after the psychosurgical operation of stereotactic subcaudate tractotomy, 1979-1991.

The outcome of all psychosurgical operations (stereotactic subcaudate tractotomies) performed at the Geoffrey Knight National Unit for Affective Disorders in London since 1979 is reviewed. Of patients who had suffered severe mood or obsessive-compulsive disorders before surgery, 84 of 249 (34%) were well 1 year after. The effects of gender, psychiatric diagnosis, and age on outcome are assessed. The findings are compared with a 1975 outcome study, and explanations for apparent differences are proposed.

Adult↗
PubMed1994

Psychiatric morbidity and illness behaviour in women with chronic pelvic pain.

Sixty-two gynaecology in-patients were screened for psychiatric disorder and illness behaviour on the eve of elective laparoscopy. Patients with chronic pelvic pain (CPP) reported significantly more depressed mood and illness behaviour than those without pain. Chronic pelvic pain patients with relevant structural pathology at laparoscopy were compared to those with negative laparoscopic findings. The two groups did not differ on measures of psychiatric morbidity or illness behaviour. They differed significantly in response to the McGill Pain Questionnaire. These findings were used to propose a self-report instrument for predicting negative laparoscopic findings in depressed CPP patients pre-operatively.

Adult↗
PubMed1994

Psychosurgery: stereotactic subcaudate tractomy. An indispensable treatment.

BACKGROUND: Stereotactic subcaudate tractotomy (SST) is the only type of psychosurgery performed at the Geoffrey Knight Unit, London, where nearly 1300 operations have been done since 1961. Statistically reliable data are not available to prove the effectiveness of SST. A detailed statement about contemporary psychosurgery is given. METHOD: Relevant publications from the Unit and via Medline are discussed. The outcome figures are reviewed. The outcome is assessed at the Unit in global and clinical terms, associated with results of self-completed questionnaires. RESULTS: SST allows 40-60% of patients to live normal or near-normal lives, perhaps with continuation of medication. A reduction in suicide rate to 1% post-operatively, from 15% in cases of uncontrolled affective disorders is seen. CONCLUSION: As a treatment of last resort, no controlled trial against a comparable treatment is possible. It appears reasonable to offer SST to patients with suicidal and deluded depression or with frequently swinging moods, not responding to other treatments.

Adult↗
PubMedDate not supplied

Practical management of treatment-resistant affective disorders.

The Geoffrey Knight National Unit was set up in 1970 exclusively for psychosurgery. In recent years it has become increasingly concerned with the development of medication regimens that might avoid the need for surgery. This has offered a unique pharmacotherapeutic opportunity because all the referrals have severe, persistent and treatment-resistant disorders. The scheme of high-dose and combined medication devised is presented and discussed.

Algorithms↗