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Biomedical subjects

A D Bangham

Publications and source records attributed to A D Bangham.

At least 37 records · Page 2Linked to original sources

Selective compartmentation of the hydration products of carbon dioxide in liposomes, and its role in regulating water movement.

Using liposomes, some possible consequences of auxin-stimulated proton secretion in plant tissues are modelled. Liposomes, made specifically permeable to protons and potassium ions, but containing at least one impermeant, swell at a rate which is proportional to the availability and hydration rate of carbon dioxide; the gas functions as a source of proton and dehydrated anion and this enables a net transfer of KHCO3 to take place.

Carbon Dioxide↗

On the question of an electrokinetic requirement for phospholipase C action.

The phospholipase C of clostridium welchii (alpha toxin) has an absolute requirement for trace quantities of Ca2+. It attacks pure phosphatidylcholine particles (smectic mesophases) having a close-packed bilayer structure only when their surface zeta potential is made positive by the addition of certain divalent ions (e.g., Ca2+) to the aqueous phase or by the presence of low concentrations of long chain cations to the lipid. Alternatively, if the rotational freedom of individual phospholipid molecules is increased by the insertion of short n-alkanols (e.g., hexanol) into the bilayer or when a monolayer of the substrate at an air/water interface is expended, enzymic hydrolysis can occur without any requirement for a net postive charge on the surface.

Amines↗

Model membranes.

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Acetates↗