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Biomedical subjects

A D Bain

Publications and source records attributed to A D Bain.

67 records · Page 4Linked to original sources
PubMed1969

Leptospirosis in human pregnancy followed by death of the foetus.

An attack of leptospirosis due to serotype canicola in a pregnant woman was followed in the convalescent period by death of the foetus. Previous cases of this nature are reviewed. In certain areas where leptospirosis is known to exist among the animal population early recognition and treatment of human cases is advised, especially when they occur during pregnancy.

Adult↗
PubMedDate not supplied

Prenatal pleural effusion associated with congenital pulmonary lymphangiectasia.

A pleural effusion associated with congenital pulmonary lymphangiectasia was detected in a fetus in utero but was absent at the time of delivery. The pleural effusion was unilateral although the disease involved both lungs. In this case there was an association between polyhydramnios and congenital pulmonary lymphangiectasia.

Adult↗
PubMedDate not supplied

A complete proton and carbon-13 NMR analysis of fluocinonide, a fluorinated corticosteroid.

This paper presents a complete analysis of the proton and carbon-13 NMR spectra of 21-acetoxy-6 alpha,9-difluoro-11 beta-hydroxy-16 alpha,17-(1-methylethylidene) bis-(oxy) pregna-1,4-diene-3,20-dione, a potent anti-inflammatory fluorosteroid. The 300 MHz proton spectrum was analyzed using a combination of the two-dimensional homonuclear chemical shift correlation (COSY) technique and one-dimensional NOE difference spectra. Exact coupling constants and chemical shifts were obtained by spectral simulation and iteration. The carbon-13 spectrum was assigned from the proton spectrum via a two-dimensional heteronuclear chemical shift experiment, and long-range fluorine-proton couplings were confirmed by a fully coupled heteronuclear COSY-type experiment.

Chemical Phenomena↗
PubMedDate not supplied

Chromosomal mosaicism in amniotic fluid cell cultures.

Six cases of chromosomal mosaicism detected in amniotic fluid cultures are described. In five of these there was no evidence of fetal mosaicism. In one case fetal mosaicism was demonstrated but only by the study of fibroblasts since blood cultures showed only normal cells. The implications of amniotic fluid mosaicism are discussed and it is concluded that this usually does not indicate fetal mosaicism. The value of repeated amniocentesis in the diagnosis of fetal mosaicism was demonstrated by findings in three of the cases. It is recommended that amniotic fluid cultures be harvested in situ for chromosome studies and that cytogenetic results be expressed as number of colonies karyotyped rather than as number of cells analyzed.

Adult↗