Search PubMed⌕ Search

Biomedical subjects

A Cusumano

Publications and source records attributed to A Cusumano.

44 records · Page 3Linked to original sources

[Giant hydatid of the left lung].

A case of giant hydatid cyst of the left lung submitted to conservative surgery is reported. The postoperative period was complicated by the appearance of a bronchopleural fistula and a residual cavity. The complication was treated with targeted double lumen drainage which enabled pleuroclysis with saline solution and betadine. The closure of the fistula, the elision of the cavity and recovery were accomplished after 95 days. These results demonstrate that conservative surgery is possible even in the presence of giant lung hydatid cyst. Major resections constitute an extreme measure.

Adult↗

Modified surgical technique for repeated epikeratophakia surgery in aphakic eyes.

BACKGROUND: Incomplete epithelial removal from the peripheral keratectomy at the time of repeat epikeratophakia surgery can lead to interface downgrowth and consequent failure, as observed in the case reported herein. We present a modification of the standard surgical technique aimed at avoiding such complication. METHODS: A 69-year-old white female underwent a third aphakic epikeratophakia modified to reduce the risk of epithelial interface downgrowth, which had caused a previous failure. The aphakic tissue lens, 8.5 mm in diameter, was sutured into a corneal pocket obtained at a deeper level, inside the peripheral keratectomy used for the previous two procedures. RESULTS: Useful visual acuity (20/60) was obtained and the refractive outcome remained stable up to 1 year postoperatively. Epithelial interface downgrowth did not recur. CONCLUSIONS: Despite the possible risk of perforation while undermining the recipient cornea at a deeper level, the modified technique might offer a more effective method of preventing epithelial downgrowth after repeat epikeratophakia surgery.

Aged↗

Electron microscopic examination of prelathed, lyophilized tissue used for epikeratophakia in humans.

Morphologic changes secondary to cryolathing and lyophilization have been described in tissue lenses used for epikeratophakia. We report the electron microscopic findings of an aphakic tissue lens which could not be used because of sudden preoperative myocardial infarction of the patient. Scanning electron microscopy revealed the presence of three distinct zones (peripheral, intermediate, and central) on the stromal side of the lens. The surface of the central zone appeared to be the smoothest, as a consequence of the different angle of lathing. The Bowman's layer side of the tissue lens exhibited a uniform, smooth surface. Transmission electron microscopy revealed a largely normal collagenous structure of both stroma and Bowman's layer. Interfibrillary distances were within normal limits. Several giant stromal spaces of various dimensions filled with homogeneous material were observed. Variably preserved keratocytes were a regular finding among the lamellae. Our findings confirmed some of the structural changes previously observed in tissue lenses not used for epikeratophakia in humans. The limited size of a smooth central zone of the posterior surface could explain some postoperative complaints such as persistent glare phenomena, as well as prolonged visual rehabilitation time, especially in those cases where centration of the epi-lens onto the recipient cornea is not optimal.

Cornea↗

Epikeratophakia for the correction of myopia: lenticule design and related histopathological findings.

In spite of the numerous changes in surgical technique, epikeratophakia for the correction of myopia is still far from achieving optimal results. The removal rate of myopic lenticules is much higher than that of aphakic or keratoconus lenticules and has prompted the FDA to deny its approval to the industrial production of epi-lenses for the correction of myopia. We report a patient who underwent epikeratophakia for the correction of high myopia in his left eye and required removal of the lenticule because of unsatisfactory visual outcome. The histologic and electron microscopic examination of the removed lenticule revealed the presence of folds in both Bowman's layer and superficial stroma. These had been described in the past and related to the surgical technique used at that time; they were thought to be the cause of poor visual acuity n two patients, and had prompted, therefore, a change in surgical technique. Our findings suggest that the present lenticule design could be responsible for the presence of folds and the consequent poor visual result.

Adult↗

[Palliative treatment of cancer of the esophagus].

Personal experience in the treatment of patients with oesophageal cancer that cannot be radically operated is presented. The high incidence (50%) of this situation required the use of measures to improve survival conditions. Results speak in favour of prosthetic intubation of the oesophagus, preferably by the endoscopic route and in a carefully selected number of patients, in the course of major operations like palliative oesophago-gastroplasty.

Adult↗