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Biomedical subjects

A Curry

Publications and source records attributed to A Curry.

104 records · Page 6Linked to original sources
PubMed1981

Demonstration of papilloma virus particles in cervical and vaginal scrape material: a report of 10 cases.

The finding of virus particles by transmission electron microscopy (TEM) in fixed cervical and vaginal scrape material and their identification as papilloma viruses by negative staining is described. The colposcopic, cytological, and histological appearances in a group of 10 patients in whom virus particles were seen are discussed and the possibly considered of an association between papilloma virus infection and the development of cervical intraepithelial neoplasia (CIN) and multifocal intraepithelial neoplasia of the female lower genital tract.

Adolescent↗
PubMed1979

Detection of herpes-simplex viral genome in brain tissue.

Herpes-simplex virus type (HSV-1) nucleic-acid sequences were detected by in-situ hybridisation in thin sections of brains from mice which had been inoculated 24 weeks previously with HSV-1. These mice were not ill, and infectious virus could not be recovered from them. HSV-1 sequences were also present in brain smears from 3 of 4 elderly patients who had died with chronic psychiatric illness and neuropathological changes but not in smears from 2 patients who had had acute psychotic episodes and minimum abnormal histology. Adenovirus type 7 nucleic-acid sequences were not detected in these human specimens.

Adenoviruses, Human↗
PubMedDate not supplied

A new class and order of myxozoans to accommodate parasites of bryozoans with ultrastructural observations on Tetracapsula bryosalmonae (PKX organism).

Tetracapsula bryosalmonae, formerly PKX organism, is a myxozoan parasite that causes proliferative kidney disease in salmonid fish. Its primary hosts, in which it undergoes a sexual phase, are phylactolaemate bryozoans. It develops in the bryozoan coelomic cavity as freely floating sacs which contain two types of cells, stellate cells and sporoplasmogenic cells, which become organised as spores. Eight stellate cells differentiate as four capsulogenic cells and four valve cells which surround a single sporoplasmogenic cell. The sporoplasmogenic cell undergoes meiosis and cytoplasmic fission to produce two sporoplasms with haploid nuclei. Sporoplasms contain secondary cells. The unusual development supports previously obtained data from 18S rDNA sequences, indicating that species of Tetracapsula form a clade. It diverged early in the evolution of the Myxozoa, before the radiation that gave rise to the better known genera belonging to the two orders in the single class Myxosporea. The genus Tetracapsula as seen in bryozoans shares some of the characters unique to the myxosporean phase and others typical of the actinosporean phase of genera belonging to the class Myxosporea. However, it exhibits other features which are not found in either phase. A new class Malacosporea and order Malacovalvulida are proposed to accommodate the family Saccosporidae and genus Tetracapsula. Special features of the new class are the sac-like proliferative body, valve cells not covering the exit point of the polar filament, lack of a stopper-like structure sealing the exit, maintenance of valve cell integrity even at spore maturity, absence of hardened spore walls and unique structure of sporoplasmosomes in the sporoplasms.

Animals↗
PubMedDate not supplied

Light- and electron-microscopic studies on multinucleated giant cells in sarcoid granuloma: new aspects of asteroid and Schaumann bodies.

Ultrastructural studies using transmission, analytical, electron, and light microscopy were performed on epithelioid granulomata in 4 lymph nodes from a case of sarcoidosis, emphasizing the organization of asteroid and Schaumann bodies in multinucleated giant cells and the deposition of chemical elements. Serial sectioning at semithin level showed a single multinucleated giant cell can contain up to 4 asteroid and 1 Schaumann body. Microtubules and centrioles were not found in asteroid bodies, although a centriolar field was present in 1 giant cell close to the plasma membrane, completely unrelated to the asteroid body. In 1 asteroid body, tubulelike structures were observed in a focus showing filament dissociation. A principal ultrastructural finding is intimate envelopment of radiating filamentous arms of the asteroid body by myelinoid membranes, extensive forms of which are also present between the arms. Elemental analysis revealed a definite peak of calcium and a probable phosphorus peak in relation to the asteroid body and associated myelinoid membranes. Calcium and phosphorus with smaller quantities of aluminum and iron were found in Schaumann bodies. Our studies indicate that organization of the asteroid body is more complex than hitherto described, independent of the centriolar and microtubular systems. Evidence for the possible developmental pathway of the Schaumann body is provided by morphological changes within myelinoid figures intimately related to the asteroid body.

Female↗
PubMedDate not supplied

Spindle cell and pleomorphic lipoma: an ultrastructural study.

Spindle cell and pleomorphic lipoma are rare benign tumors of adipose tissue. Their histogenesis is poorly understood and pleomorphic lipoma has not previously been studied ultrastructurally. This study describes the morphology and ultrastructure of 6 cases of spindle cell and pleomorphic lipoma. Both spindle cell and pleomorphic lipomas showed similar ultrastructural features with an interrupted basal lamina, occasional non-membrane-bound lipid vacuoles and abundant rER. In all the cases mast cells were conspicuous and were intimately related to both spindle and pleomorphic cells. It is proposed that both the spindle and pleomorphic multinucleated cells that characterize these tumors are prelipoblastic mesenchymal cells. The possible significance of an interaction between these cells and mast cells is discussed.

Cell Nucleus↗
PubMedDate not supplied

Caring for the bicultural family: the Korean-American example.

Bicultural families are increasing in US society, and family physicians will see more of these families for medical care. They can exhibit problems unique to their bicultural experience that arise from the stresses caused by cultural differences in such areas as family roles, emotion expression, child rearing, interpersonal relationships, and methods of communication. If coping mechanisms do not resolve these stresses, the family will come to the family physician with physical manifestations of illness or distress. The symptoms are usually related to depression or depressive equivalents. To care for these families successfully, family physicians should treat both family members and the individual patient. When caring for bicultural families, it is important to recognize the high-risk factors that put them at risk for dysfunction. Treatment goals should be centered on communication and education. In short-term counseling, support, education, listening, and referral to appropriate community resources are useful treatment modalities.

Acculturation↗