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Biomedical subjects

A Cuarón

Publications and source records attributed to A Cuarón.

At least 19 recordsLinked to original sources

Tables to estimate total binding capacity of thyroxine-binding globulin from the in vitro thyroid function tests.

Equations for an estimate of the total binding capacity of serum thyroxine-binding globulin (TBG-TC) were developed relating this parameter to serum thyroxine concentration (T4) and in vitro uptake (T3U). This extimate demonstrated a highly significant, positive correlation with TBG-TC as measured by electrophoresis in ten normal subjectdividuals with altered TBG-TC but without thyroid dysfunction (ten normal pregnant women, ten healthy women receiving anovulatories, ten nephrotics, and ten patients with severe malnutrition). True-positive (sensitivity) and true-negative (specificity) ratios were calculated for total and free T4 in serum, T3U, Free T4 Index, and both measured and calculated TBG-TC. False-positive results for free T4 index (12%) were due to altered TBG-TC. In such cases, 93% were recognized by the calculated TBG-TC from the calues of the invitro tests. It is concluded that this estimates should be added to the in vitro thyroid tests for their proper interpretation in cases where altered TBG-TC could be misleading. This estimate applies only to the particular in vitro testing system used herein.

Anovulation↗

[Scintigraphic criteria for the diagnosis of pulmonary embolism].

The natural history of pulmonary embolism is described, together with the physiopathologic alterations and the clinical manifestations of this disease, correlating these with the various patterns of pulmonary perfusion usually found by lung scintigraphy with 99mTc-MAA in patients with thromboembolic lung disease. By using data found in the literature, the operating characteristics (sensitivity, specificity, and accuracy) and the predictive values of the different scintigraphic patterns, were calculated for populations with different prevalences of pulmonary embolism. It is concluded that perfusion lung scintigraphy is a non-invasive, objective and fast procedure, very sensitive to alterations of the regional blood flow, but that is not specific for embolism. In some cases it can replace pulmonary angiography but in others, its results may indicate the performance of invasive procedures.

Humans↗

[Pulmonary scintigraphy using the inhalation of monodispersed radioactive aerosols. Preliminary report].

This article describes a method for inhalatory lung scintigraphy (ILS) by the use of radioactive monodisperse aerosols, with particles smaller than 2 microns. We discuss the findings in normal subjects, in patients with pulmonary embolism (PE) or/and obstructive pulmonary disease (OPD), and in individuals with severe pulmonary hypertension. This procedure has several advantages over the use of radioactive gases, such as 133Xe and 81Krm: lower cost, easier to perform, several scintigraphic projections in one study, acquisition of perfusion and inhalatory images in a single session, and inhalatory and perfusion images with identical spatial resolution and similar data density. It is concluded that ILS with radioactive monodisperse aerosols is a useful method for the study of OPD and in conjunction with perfusion lung scintigraphy is helpful in the diagnosis of PE.

Aerosols↗

[Digital radiocardioangiography as an auxiliary method for the precise localization of zones of myocardial concentration of 99mTc-Sn(II)-pyrophosphate. Preliminary report].

A new method is introduced for the superposition of 99mTc-pyrophosphate (PiF) myocardial images on the isolated images of the radioangiocardiographic dextrophase and levophase, in order to include cardiac anatomical references for the accurate topographic localization of the PiF concentration areas. Results in two different patients are presented. In one of them, the PiF concentration was evident at the inferoseptal, inferoapical and posterolateral regions of the left ventricle. In the other, the PiF concentration was evident at the same areas than in the former plus the inferoanterior region of the right ventricle. Our project is to validate this procedure by correlating its results with those obtained through other clinical methods that detect right ventricular infarction.

Angiocardiography↗