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Biomedical subjects

A Csontai

Publications and source records attributed to A Csontai.

At least 19 recordsLinked to original sources

The response of balanitis xerotica obliterans to local steroid application compared with placebo in children.

PURPOSE: We evaluated the clinical effectiveness of topical steroid application for balanitis xerotica obliterans in children and analyzed the association of any clinical response with histological findings. MATERIALS AND METHODS: Our double-blind, placebo controlled, randomized study included 40 boys in whom balanitis xerotica obliterans was diagnosed clinically by cicatricial phimosis. The severity of phimosis was graded into 4 groups. Patients were randomized to receive the topical application of 0.05% mometasone furoate or placebo. After 5 weeks phimosis severity was reevaluated and all patients underwent circumcision. Surgical specimens were histologically typed as an early, intermediate or late form of balanitis xerotica obliterans. RESULTS: Seven patients were withdrawn from the study. In the steroid group 7 boys had clinical improvement and 10 had no change. Histological study showed an early, intermediate and late form of balanitis xerotica obliterans in 5, 5 and 7 cases, respectively. Of cases with clinical improvement 5 were the early and 2 the intermediate type. In the placebo group 5 cases worsened clinically and 11 did not change. Histological evaluation revealed an early, intermediate and late form of balanitis xerotica obliterans in 3, 7 and 6 boys, respectively. Of the 5 cases with histological worsening, disease was the early, intermediate and late type in 2, 2 and 1, respectively. CONCLUSIONS: Applying a potent topical steroid affects improvement in balanitis xerotica obliterans in the histologically early and intermediate stages of disease, and may inhibit further worsening in the late stage.

Administration, Topical↗

[Laparoscopic intervention in pediatric urology].

The authors summarise the short history of the laparoscopy, and main steps of its use in international and Hungarian practice of urological surgery. They evaluate the possibility of laparoscopy in paediatric urological practice. Finally, they present their experience with this minimally invasive technique from 1995. Between October 1995 and September 1998, 83 laparoscopic procedures were performed. In 59 patients the vena testicularis were ligated by laparoscopy and in 22 patients 24 non palpable testes were diagnosed and operated. In 9 of the cases laparoscopic orchidopexy was performed. The authors demonstrate their operative technique. All laparoscopic interventions were tolerated well by children and they were treated without any complication. Postoperative pain medication were given for 5 children. The operative time for varix ligation ranged from 15 and 20 minutes, and for laparoscopic orchidopexy from 30 and 40 minutes. The recurrence rate of varicocele was found to be 1.5%, and postoperative hydrocele developed in one patient (1.5%).

Adolescent↗

Xanthine stone in the urinary bladder of a male child.

Urinary tract calculi composed primarily of xanthine are rate both in adults and children. We describe the clinical presentation and management of a 3.5-year-old boy with hereditary xanthinuria (an autosomal recessive disorder of purine metabolism) and primary bladder calculus formed from xanthine. To our knowledge this case demonstrates a previously undescribed form of xanthinuria in childhood. Xanthine stones, although rare, should be considered in the diagnosis of urolithiasis.

Child, Preschool↗

Laparoscopic varicocele operation: a chance to prevent the recurrence.

There are recurrences and postoperative hydrocele of varicocele after any kind of surgical treatment. Laparoscopic clipping and dissection of internal spermatic vessels was performed without any complication in 73 children to treat varicocele in our department between 1995 and 1998. We have used a new method to detect etiological factors at laparoscopic surgery. The well-known Linton and Trendelenburg test was adapted to detect incidental collateral veins in 73 patients. Using these test, collateral veins were detected in 16 boys. The testicular artery identified in most of the cases as a pulsatile vessel. The operating time was 10-25 minutes. Laparoscopic varicocelectomy is a safe, effective treatment causing minimal discomfort and allowing patients an early to return to activity. These results suggest this technique a viable alternative to open ligation in paediatric urological practice.

Adolescent↗

Intrascrotal and testicular solid masses in childhood.

A retrospective study was performed between 1985 and 1994 on paediatric patients operated for asymptomatic intrascrotal or testicular palpable masses. Tumour was suspected in each case and it was surgically explored. Twenty-six children were affected, their age ranging between 9 days and 14 years. In 11 cases testicular torsion, in 4 epididymitis and in another 2 dystrophic calcification were found. Tumours, including rather rare alterations, were observed in only 9 children. The present results draw attention to the tumour-like occurrence of testicular torsions and other benign alterations of the scrotum.

Adolescent↗

[Non-surgical approach to the treatment of vesico-ureteral reflux in childhood].

The authors report about their point of view, based on their experience treating children with vesicoureteric reflux (VUR) in the last two decades. 812 children were treated for VUR between 1973-1992. In 62 (7.6%) due to the parenchymal damage, primary nephrectomy was made, antireflux operations were done in 227 (30.3%). Without surgery, recovery or significant improvement was achieved in 523 children (69.7%). The basis of the good results with conservative therapy is in their opinion the thorough knowledge of the function of the urinary organs, especially of the urinary tract, and the precise detection of the pathophysiological processes leading to VUR. The conditions in which antireflux surgery is avoided, are discussed in details, emphasizing the situations and methods eventually leading to mistakes, e. g. the improper judgement of VUR detected during acute pyelonephritis or during an incorrectly performed micturition cystography, and the undiagnosed damaged bladder function. Essential is therefore to clarify the etiology of the VUR and the compensated/uncompensated state of the urinary tract, the clinical condition of the child. Antireflux operation is necessary only if in the renal parenchymal damage the role of the VUR is obvious and it can be prevented only with surgery.

Adolescent↗

Isotope diagnostics, CT and MR in urinary tract diseases of infants and children.

Ninety-nine isotope, 4 CT and 10 MR examinations were carried out in 1990 to test urogenital disorders in infants and children. The procedures are described with sidelights on indication, difficulties of technical nature and comparison with internationally published reports. An examination strategy is devised, with estimation of its effectiveness in the follow-up and after-care.

Child↗

Results of surgical treatment in children with bladder exstrophy.

A series of 42 children (30 boys and 12 girls) underwent surgery for bladder exstrophy between 1972 and 1989. Primary bladder closure was performed in 11 patients and was successful in 6. Four of these children are about 2 years old and so it is not yet possible to assess their continence. Ureterosigmoidostomy was performed in 35 children, one of whom was converted to cutaneous ureterostomy. Follow-up ranges from 2 to 20 years (average 9 years 3 months) and 50% of the patients are symptom-free. The most frequent problems were acidosis and urinary tract dilatation. Other complications, such as hypokalaemia and pyelonephritis, were seldom seen. Although ureterosigmoidostomy has some disadvantages, our patients have adapted well and lead a normal life.

Adolescent↗

Surgical treatment of vesicoureteral reflux.

Based on the critical analysis of their own material, the authors evaluate the different antireflux operations. The problems of surgical indication are dealt with. The principles applied in selecting the type of operation are reviewed and the experiences of the control examinations are reported.

Adolescent↗

Effect of levamisol on cellular and humoral immune reactivity and on recurrences in patients with bladder papilloma.

Ten patients who had undergone repeated surgical interventions for bladder papilloma with successive recurrences within intervals of a few months, were given levamisol in weekly doses of 300 mg over a year, and were followed up for various cellular immune reactions, as well as for serum globulin and for acute-phase protein concentrations in the course of treatment. Levamisol was found to act primarily on cell-borne responsiveness. The recurrence-free intervals increased in the course of treatment. Four patients have remained free from recurrences since the start of treatment.

Aged↗

[An operated case of bilateral kidney tumor].

In a case of bilateral kidney tumour, contralateral tumour resection was performed after unilateral nephrectomy. One and a half years later the patient has no complaints. The importance of partial nephrectomy in such cases is stressed.

Adenocarcinoma↗

Diagnosis and treatment of adult polycystic kidney disease.

The methods applicable to the diagnosis of polycystic kidney disease are reviewed. By assessing the clinical data of 314 patients suffering from adult polycystic kidney disease who had been treated in the 30 years between 1950 and 1979, the importance of conservative therapy and nephrological care is emphasized. The significance of hemodialysis in therapy and the special circumstances of transplantation are discussed. The indication of surgical treatment can be extended in complication-free cases.

Adolescent↗

Bladder-flap plasty in disturbances of urine transport.

Late results of the bladder-flap method Boari--Mezö fulfilled expectations only in the correction of ureteral lesions of gynaecological origin. With appropriate technique even 5 to 10 cm long sections of the ureter can be replaced and in one-third of the cases the late results, too, are good. The authors are convinced that Boari plasty is not an anti-reflux operation and the results are poor in cases of specific ureteral stricture. The operation is recommended for the correction of congenital malformations, fibrous periureteritis and strictures after nephrolithotomy when the strictures are long and simple ureteral neoimplantation is technically impossible.

Female↗

Local application of THIO-TEPA in the prevention of recurrent papillary carcinoma of the bladder.

Prophylactic total THIO-TEPA treatment was employed in 44 cases over a period of five years, following radical surgery (including reoperations) for recurrent vesical papillomatosis or carcinoma, and numerous subsequent transurethral coagulations or resections owing to multiple recurrences. Three patients have been now free from recurrences for five years, 13 patients for four years, 11 patients for three years and 9 patients for two years. Eight patients proved unresponsive, the recurrence rate having remained unaffected. No toxic effects requiring any special measures were encountered.

Administration, Topical↗

[Condyloma acuminata].

A review of the clinical features and therapeutic possibilities of condyloma acuminatum is presented on the ground of the ten-year experience of the authors. A giant condyloma simplex with benign clinical behaviour and typical histologic pattern and a case of epithelioma starting from a condyloma simplex and leading to the amputation of the penis are described.

Adult↗

Horseshoe kidney and its therapeutic problems. (A review of seventy-one clinical cases).

A review of 71 cases of horseshoe kidney accounting for 0.12% of the total number of patients seen at the Department of Urology, Semmelweis University Medical School, Budapest, over 25 years is presented. The incidence of the abnormality has been found twice as high in males as in females. The proportion of surgical cases has been 57.8%, in agreement with published data. The radiodiagnostic investigations, particularly the functional diagnostic studies, are dealt with in detail. Their decisive importance in the considerations for or against surgery is emphasized.

Adolescent↗