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Biomedical subjects

A Csendes

Publications and source records attributed to A Csendes.

At least 199 records · Page 11Linked to original sources
PubMed1978

Gastric emptying in patients with reflux esophagitis or benign strictures of the esophagus secondary to reflux compared to controls.

Quantitative measurements of gastric emptying of fluids were performed in 11 controls, 12 patients with reflux esophagitis, and in 7 cases with benign strictures of the esophagus secondary to reflux. The method for measuring gastric emptying was the double-sampling test with phenol red as an inert marker. No significant alterations in gastric emptying were noted in reflux patients or in stricture patients compared to controls, although a tendency to a slower emptying was noticed in the latter group. The importance of these findings is discussed.

Adolescent↗
PubMed1978

Gastroesophageal sphincter pressure and serum gastrin studies following food intake before and after vagotomy for duodenal ulcer.

Gastroesophageal sphincter pressure (GESP) and serum gastrin concentration (SGC) were determined in the basal state and after a protein meal in 6 patients with duodenal ulcer (DU) 6 patients after parietal cell vagotomy (PCV) 6 patients after selective gastric vagotomy plus drainage (SGV + D), and 6 patients after selective gastric vagotomy plus precise antrectomy (SGV + A). No correlation in the resting state between GESP and SGC was observed. After food ingestion, DU patients showed a sustained rise in GESP which lasted up to the end of the experiment. The vagotomized patients, however, showed no rise in sphincter pressure after food intake--rather a tendency to decrease in pressure occurred. On the contrary, SGC rose significantly after food ingestion in patients with SGV + D or PCV, while in DU patient this rise was less significant. Patients with vagotomy and antrectomy showed no rise in SGC. These results do not suggest that SGC and extrinsic vagal innervation in the resting state play a significant role in the maintenance of the tone of GES. After food ingestion an interaction may occur between intact vagal innervation and rise in SGC in order to obtain an adequate rise in GESP.

Adult↗
PubMed1978

Relation of gastroesophageal sphincter pressure and esophageal contractile waves to age in man.

Gastroesophageal sphincter pressure (GESP) and contractile waves of the esophagus were measured in 113 normal subjects ranging in age between 2 months and 74 years. The amplitude and duration of the peristaltic waves of the thoracic esophagus were similar in both children and adults. Resting GESP pressures were dependent upon age. In children under one year, high pressures were recorded. The high pressures gradually diminished until between 15 and 24 years, whereafter they remained at similar values up to 65 years. After this age, a further decline in pressure was observed. The importance of these findings are discussed.

Adolescent↗
PubMed1978

Gastroesophageal sphincter pressure and serum gastrin: reaction to food stimulation in normal subjects and in patients with gastric or duodenal ulcer.

Gastroesophageal sphincter pressure and serum gastrin concentration were determined in the fasting state and after the intake of a protein food in 6 normal subjects, 6 patients with gastric ulcer, and in 6 patients with duodenal ulcer. No significant differences in the fasting state were found. After the food intake, gastroesophageal sphincter pressure increased significantly over basal values in normals and in patients with duodenal ulcer, but in patients with gastric ulcer a decrease in pressure was noted. Serum gastrin rose in all subjects studied after the food stimulation, but it was significant only in the gastric and duodenal ulcer group. In two normals and two patients with duodenal ulcer the ingestion of a potato meal of similar weight to that of the protein meal showed no change either in serum gastrin or in sphincter pressure. In one additional normal subject and one duodenal ulcer patient the constant intravenous infusion of Aminosol for 2 h produced no change in serum gastrin or sphincter pressure. These results indicate that the effect of protein food on sphincter pressure is different for gastric or duodenal ulcers, and, furthermore, that this effect is mediated by proteins in the gastrointestinal tract.

Adolescent↗
PubMed1978

Gastroesophageal sphincter pressure and serum gastrin studies following food intake before and after vagotomy for duodenal ulcer.

Gastroesophageal sphincter pressure (GESP) and serum gastrin concentration (SGC) were determined in the basal state and after a protein meal in six patients with duodenal ulcer (DU), six patients after parietal cell vagotomy (PCV), six patients after selective gastric vagotomy plus drainage (SGV + D), and six patients after selective gastric vagotomy plus precise antrectomy (SGV + A). No correlation in the resting state between GESP and SGC was observed. After food ingestion, DU patients showed a sustained rise in GESP which lasted up to the end of the experiment. The vagotomized patients, however, showed no rise in sphincter pressure after food intake--rather a tendency to a decrease in pressure occurred. On the contrary, SGC rose significantly after food ingestion in patients with SGV + D or PCV, while in DU patients this rise was less significant. Patients with vagotomy and antrectomy showed no rise in SGC. These results do not suggest that SGC and extrinsic vagal innervation in the resting state play a significant role in the maintenance of the tone of GES. After food ingestion an interaction may occur between intact vagal innervation and rise in SGC in order to obtain an adequate rise in GESP.

Adult↗
PubMed1978

Incidence of gallstones development after selective hepatic vagotomy.

The incidence of gallstone development after selective hepatic vagotomy was evaluated in a prospective study, comparing it with a control group. There were 26 subjects with normal gallbladder, who were studied 3 to 5 years later and compared with 22 patients with reflux esophagitis who were operated and followed in a similar way. In all patients a selective hepatic vagotomy was performed as part of the posterior gastropexy. All had oral cholecystograms before and after surgery. In normal subjects 2 of the 26 cases (7.7%) and in the operated patients 9 of the 22 (41%), showed gallstones during the second evaluation. This incidence is statistically different. The importance of this finding is discussed.

Adult↗
PubMed1977

[Is basal hypersecretion an indication of the presence of Zollinger-Ellison syndrome?].

Twenty patients with gastric basal hipersecretion over 15 mEq/hr and a suspicion on a Z-E syndrome or gastrinoma were studied by means of histamin gastric analisis, calcium test and measurement of lower esophageal sphincter pressures. In none of them a pancreatic tumour was found at operation, being their post-operative course normal up to a 60 months follow-up. The use of these everyday techniques is proposed for medical centers which have no facilities for gastrin radioimmunoassay techniques.

Adult↗
PubMed1976

Manometric studies on the human pyloric sphincter. Effect of cigarette smoking, metoclopramide, and atropine.

Pyloric sphincter pressure was assessed with water-perfused polyvinyl tubes. Smoking one cigarette significantly decreased the basal pyloric pressure, whereas 10 mg of metoclopramide as an intravenous bolus increased the pyloric pressure in normal subjects and in patients with gastric ulcer with low basal pressure. Duodenal acidification with 0.1 N HCl significantly increased pyloric pressure. Atropine 15 mug per kg, subcutaneously prevented the rise of pyloric pressure in response to acid infusion into the duodenum.

Adult↗