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Biomedical subjects

A Cornu-Thenard

Publications and source records attributed to A Cornu-Thenard.

12 recordsLinked to original sources

Pregnancy-induced changes in lower extremity superficial veins: an ultrasound scan study.

OBJECTIVE: The purpose of this study was to follow changes in superficial veins of the lower extremities during pregnancy and the postpartum period in women with varicose veins. METHODS: This was a prospective study with the use of duplex scanning during the first and third trimesters of pregnancy and postpartum period. Competent veins were defined as veins with an absence of reflux, and incompetent veins were defined as veins with reflux. The diameter of the competent or incompetent greater saphenous vein (GSV) and lesser saphenous vein (LSV) was measured. The diameter of the largest varicose dilatations was measured in all three networks: GSV and its tributaries, LSV and its tributaries, and nonsaphenous varicose veins. RESULTS: Sixty-six women were studied prospectively (mean age, 32.2 +/- 4 years; 85 affected extremities). The diameter of competent and incompetent GSVs and competent LSVs increased between the first and third trimester (P <.001) and decreased between the third trimester and the postpartum period (P <.001). The diameter of the largest varicose dilatations of the GSV and its tributaries and nonsaphenous networks increased between the first and third trimester (P <.001) and decreased between the third trimester and the postpartum period (P <.001). No statistically significant variation of the diameter was demonstrated for any of these veins between the first trimester and the postpartum period. CONCLUSION: The diameters of competent and incompetent superficial veins increased during pregnancy and decreased during the postpartum period to return to their baseline values.

Adult↗

Chronic venous disorders of the leg: epidemiology, outcomes, diagnosis and management. Summary of an evidence-based report of the VEINES task force. Venous Insufficiency Epidemiologic and Economic Studies.

BACKGROUND: To critically review the classification, epidemiology, outcomes, diagnosis and treatment of chronic venous disorders of the leg (CVDL), to issue evidence-based recommendations, and to identify areas requiring further research. METHODS: Articles identified by an extensive literature search were scored by members of an international task force. Only those articles with a moderate or strong rating for internal validity were retained. RESULTS: A scoring system weighing CVDL severity according to the probability of ulcer occurrence is proposed. Epidemiological data on the frequency of CVDL and its risk factors are reviewed. The following items are evaluated: costs associated with treatment; clinical outcomes related to CVDL and its treatment; available generic and disease-specific measures of quality of life; diagnostic procedures used to detect venous reflux; and efficacy of available treatments. CONCLUSIONS: CVDL is an important public health problem, based on its prevalence, cost and impact on quality of life. High-priority areas for research on CVDL are identified.

Chronic Disease↗

Sclerotherapy. Continuous wave Doppler-guided injections.

BACKGROUND: The usual method of injection of sclerosing agents is based simply on clinical recognition and visualization of the varicose vein. OBJECTIVE: The authors present an original technique for sclerosing injections, named Doppler sclerotherapy. The purpose is to allow more accurate sclerotherapy in situations where varicose veins (usually greater than 4-5 mm) are not palpable in the supine position, but palpable when standing. METHODS: This technique consists of injecting the sclerosing agent using an uncomplicated continuous wave Doppler, a syringe, and a needle, according to a method consisting of four well-defined steps ensuring avoidance of arterial vessels and constant appreciation of the varicose vein to be treated, even during the injection. It requires no assistants and allows the treating physician's gaze to remain at the injection site while listening for very specific Doppler sounds of aspiration and injection. RESULTS: In our multicenter study of 220 patients (approximately 1,400 injections) all but 18 injections were successful for intravascular localization. No serious complications were noted. CONCLUSIONS: The principal indication is the treatment of varicose veins that are palpable while standing but impalpable in the supine position. In addition varicose veins in the groin region, lower third of the thigh, and along the axis of the small saphenous vein may be treated with this technique. In these situations it is a more accessible, faster, and economical technique, although it does not replace duplex ultrasound-guided injections.

Clinical Protocols↗

Importance of the familial factor in varicose disease. Clinical study of 134 families.

BACKGROUND: The role of heredity in the development of varicose veins of the lower limbs has been raised many times in the literature. When evaluating this role, most authors only question the patients, without examining their relatives. As shown in other papers, the subjectivity of this type of data throws doubt on the results. OBJECTIVE: This problem was evaluated by means of a prospective study based on clinical examination of all immediate family members. METHODS: In the case-control study, the female or male patients had to satisfy the following criteria: 1. Varicose veins in their legs. 2. Age between 30 and 40 years (meaning that, in most cases, their parents were still alive). 3. No history of deep vein thrombosis. To limit the influence of certain confusing factors (diet, life-style), the control group was composed of the patients' spouses, who were not suffering from varicose veins. The parents of the cases and the parents of the controls were also examined. For each case-control couple and for the four parents, we recorded the history of venous disease, the life-style, and the results of clinical examination, including the results of palpation and percussion of the various varicose vein territories. RESULTS: One hundred and thirty-four families were examined: 67 patients and their parents and 67 controls and their parents. A total of 402 subjects were examined. The results demonstrated a prominent role of heredity in the development of varicose veins (P < .001). The risk of developing varicose veins for the children was 90% when both parents suffered from this disease, 25% for males and 62% for females when one parent was affected, and 20% when neither parent was affected.

Adult↗

[A swollen, febrile leg].

The authors report the case of a young man, of Algerian origin, with edema of the right lower limb accompanied by an inflammatory syndrome present for several months. This symptomatology, clinically suggestive of a deep venus thrombosis, but not confirmed by sonography, proved to be due in fact to pulmonary tuberculosis with septicemic spread to the muscle masses of the right calf. The diagnosis was made by direct paracentesis of the right calf. It is important to remember that pulmonary tuberculosis with septicemic spread to muscle masses but without bone lesions remains rare. The special interest of this case thus concerns its tuberculous etiology and clinical similarity to a deep venous thrombosis. Nevertheless, the diagnosis should have been eliminated earlier in view of the clinical course and worsening of systemic manifestations.

Adult↗

[Leg ulcers in the obese: data from the literature].

The authors survey 131 publications on the epidemiology of leg ulcers in the obese patient, by successively interrogating computer data banks. By analysing this information they aim to determine the frequency of obesity in a population of patients with stasic ulcers, to see whether the ulcer has particular clinical characteristics in the obese patient, and finally, to know whether obesity affects the speed with which the ulcer heals. The results are given and assessed.

Humans↗

[Leg ulcers of venous origin. Rate of basic healing. Practical consequences].

The formula necessary for this study includes seven points of which the most important is the measurement of the reduction of the surface area of each ulcer. 100 leg ulcers, venous in origin, and representing a total surface area of 2.052 cm2, healed at varying speeds, directly proportionate to their initial surface area. To each surface area of ulcer there corresponds a length of time of half the cicatrization, equalling or less than thirty days which makes it possible to establish a point of reference in the development of cicatrization, and therefore a basic short-term prognosis. Once this time has passed, the diagnosis and the treatment are again the issue, with all that involves.

Humans↗