Search PubMed⌕ Search

Biomedical subjects

A Corno

Publications and source records attributed to A Corno.

62 records · Page 4Linked to original sources
PubMed1984

Cardiac rhabdomyoma: surgical treatment in the neonate.

Primary cardiac tumors are rare. Of the benign lesions, rhabdomyoma predominates in infants and children. The natural history of patients with cardiac rhabdomyoma is poor. About 50% die in the first month of life and 80% by 1 year of age. We report on the two youngest infants ever operated upon successfully for removal of symptomatic ventricular cardiac rhabdomyoma. The operations were performed through a left ventriculotomy in one and through a right ventriculotomy in the other during the first day of life.

Cardiac Output, Low↗
PubMed1982

Univentricular heart: can we alter the natural history?

Surgical treatment must be considered for patients with univentricular heart in view of their poor natural history. Since one of the major factors influencing the natural history of this malformation is the amount of pulmonary blood flow, we discuss the potential surgical options by separately considering the two main pathophysiological situations: univentricular heart with restricted pulmonary blood flow, and univentricular heart with unrestricted pulmonary blood flow. We have reviewed the early and late results of surgical treatment based on our experience with 19 patients and the data from the literature. Temporary relief of symptoms can be provided by palliative operations (systemic-pulmonary shunt, atrioseptectomy, enlargement of the outlet foramen, pulmonary artery banding, or palliative Mustard or Senning procedure). "Corrective" surgery, by means of either a modified Fontan operation or ventricular septation, carries a high early mortality (about 30%) and a high early and late morbidity, with only 50% of survivors enjoying an asymptomatic life. Studies of the long-term efficacy of palliative operations as well as our experience and that of others with "corrective" operations, which have a relatively short follow-up, do not yet indicate whether presently available surgical procedures can alter the natural history of patients with univentricular heart.

Adolescent↗
PubMed1982

Simplified thoracic approach to the ascending and descending aorta in complex coarctation.

Two patients with left ventricular and proximal aortic hypertension secondary to diffuse hypoplasia of the aortic arch have recently been treated by a surgical technique based on: I simultaneous exposure of the ascending and descending thoracic aorta through a left antero-latero-posterior thoracotomy; 2 insertion of a Dacron graft between the aortic root and the descending thoracic aorta. In both cases equal systemic pressures in the ascending and descending thoracic aorta and adequate distal perfusion were obtained.

Aortic Coarctation↗
PubMed1982

[Selective inhibition of hepatic gluconeogenesis gy tryptophan administration].

The levels of quinolinic acid in liver and kidney and the gluconeogenic capacity in these tissues were determined in rats treated with tryptophan. The administration of this aminoacid produced a high increase in the hepatic quinolinic acid concentrations fed and 48 h. starved rats. On the contrary, only slight variations in the concentrations of renal quinolinic acid were observed. The highest value raised in these conditions was three times lower than Ki of the quinolinic acid for the phosphoenolpyruvate carboxykinase. These results suggest that tryptophan administration originates a selective inhibition of hepatic gluconeogenesis.

Animals↗
PubMedDate not supplied

Renal effects of low dose aprotinin in pediatric cardiac surgery.

Two groups of 15 children aged from 15 days to 6 years, undergoing surgery on cardiopulmonary by-pass for congenital heart disease have been retrospectively analyzed. Group A received a low-dose aprotinin treatment (30,000 KIU/kg in the priming solution); group C (control group) did not receive any aprotinin. Groups were homogeneous for pathology, cardiopulmonary by-pass time, aortic cross-clamping time, cyanotic/acyanotic patients ratio, temperature during cardiopulmonary bypass. A number of postoperative data were measured: activated clotting time was without any difference between aprotinin-treated and control patients; the same went for temperatures, urine output, intubation time, stay in Intensive Care Unit, coagulation tests, platelet counts, hematocrit, survival rate, and blood loss. Serum creatinine levels were significantly higher in group A than in group C both at the arrival in Intensive Care Unit (0.81 +/- 0.27 vs 0.66 +/- 0.12, p = 0.032) and in the first postoperative day (1.01 +/- 0.5 vs 0.72 +/- 0.19, p = 0.038). BUN was significantly higher in group A vs group C in the first postoperative day (43.6 +/- 21.1 vs 33.9 +/- 16.7, p = 0.043). We conclude that low-dose aprotinin did not reduce postoperative bleeding; we cannot exclude that higher dosages could be more effective, but the evidence of a moderate tubular function impairment suggests caution in using high-dose aprotinin in children.

Aprotinin↗