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Biomedical subjects

A Clegg

Publications and source records attributed to A Clegg.

50 records · Page 3Linked to original sources

Natural killer cell activity and response to phytohaemagglutinin compared with the histological diagnosis of patients with transitional cell carcinoma of the bladder.

In vitro tests of immune reactivity in patients with transitional cell carcinoma (TCC) of the urinary bladder were compared with the clinical and histological diagnosis. Response of peripheral blood lymphocytes to the mitogen phytohaemagglutinin (PHA) tended to be reduced in patients with more advanced disease, although the difference between patients with advanced disease and those with early disease or controls was not statistically significant (P greater than 0.05). Assessment of natural killer (NK) cell activity in the same patients showed no change in levels of reactivity at any stage of the disease. There was no difference between the NK cell activity of patients with TCC of the bladder and normal controls.

Aged↗

Studies on the antitumour effects of N-137.

The antitumour properties of the drug N-137 were assessed in vivo in two murine T lymphoma models and two naturally metastatic hamster fibrosarcomas of Herpesvirus hominis aetiology. N-137 therapy caused a significant delay in the subcutaneous growth rate of both lymphomas (EL4 and TLX9) and in many cases completely prevented tumour appearance when administered at high doses. The antitumour effect observed in both systems was shown to be dose dependent. In contrast, N-137 therapy failed to influence the growth of two hamster fibrosarcomas (HSV-333-2-26 Met A and Met B lines), and drug administration prior to or following resection of Met B tumours failed to influence the development of natural metastases as measured by monitoring animal survival.

Animals↗

Standards of cleansing and sterilization of infant feeding utensils in the home.

Microbiological standards achieved by mothers when sterilizing babies' feeding utensils in the home were studied in the Slough area in England. Results indicated a marked improvement in this aspect of baby hygiene when compared to results of a similar survey conducted in the town of Reading, England, in 1970. Previously, 78% of bottles and 70% of the teats were recorded as being satisfactorily sterilized. During this study the number of sterile bottles had risen to 98.1%, sterile teats to 90-6%. These improved standards may be an indication of better education of mothers.

Bottle Feeding↗

Health needs assessment in intermediate care of elderly people.

The National Service Framework for older people (Department of Health (DOH), 2001a) identifies health promotion as one of the eight standards for improving the health and well-being of older people. Population health needs assessment is the first stage in any public health promotion cycle. This article critiques health needs assessment methodology, investigates the origins of health needs assessment and discusses the application of health needs assessment theory in a community hospital setting.

Aged↗

Evaluation of multidisciplinary notes.

The introduction of multidisciplinary notes can provide benefits to staff and patients alike. In this report, Angela Clegg and Carolyn Meston outline their experiences at the Bradford Community NHS Trust.

Attitude of Health Personnel↗

Getting into business: how nurses can make a difference.

In this article, the authors explore some of the key concepts and practices associated with the 'business of nursing' and look at the opportunities presented to nurses for taking a greater role in important business decisions.

Commerce↗

Leadership: improving the quality of patient care.

The satisfaction staff achieve from their work is in part determined by the style of management they work under. This article analyses the impact of a proactive leadership style on team performance and the quality of patient care.

Aged↗

Advanced nursing practice in intermediate care.

Initiatives in intermediate care are mainly nurse-led and, as nursing practice becomes more advanced, nurses need to consider the professional, ethical and legal implications.

Humans↗

Cultural sensitivity: a practical approach to improving services.

Reports commissioned by the Department of Health (Acheson 1998, Alexander 1999) have highlighted the failure of the NHS to provide culturally sensitive services for black and Asian patients. Cultural sensitivity in nursing is the provision of care that is sensitive to the needs of clients from all cultures. The authors outline the action taken to improve cultural sensitivity in a community hospital.

Black or African American↗

Halfway home.

Explore the source record for details and available documents.

Adult↗

Face value.

Explore the source record for details and available documents.

Adaptation, Psychological↗

The effectiveness of nursing care after discharge from hospital.

Increasing pressures on health care services point to a growing role for post-discharge nursing care. Yet, the evidence concerning such aftercare services has been questioned. This article discusses a systematic review of research on the effectiveness of nursing care after discharge from hospital. The review shows that such care provides no additional benefits compared with usual care.

Aged↗