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Biomedical subjects

A Clavel

Publications and source records attributed to A Clavel.

46 records · Page 3Linked to original sources

Inflammation of the coronary arteries in patients with unstable angina.

During surgery, 21 patients undergoing coronary artery bypass for unstable angina were found to have "red lines" overlying one or more coronary arteries. Adventitial biopsies showed vascular distention and inflammatory cells. The group was followed for an average of 54 months (14 to 68 months). There were no operative deaths. Recurrent myocardial ischemia developed in 38.1% (8/21); recurrent angina developed in 23.8% (5/21) and are being treated medically; myocardial infarction occurred in 9.5% (2/21); and reoperation was required in 4.8% (1/21). There was also one late death from a brain tumor. We suggest that the presence of adventitial inflammation may represent an aggressive, variant form of atherosclerosis and a less favorable clinical prognosis.

Journal Article↗

Adjunctive operative coronary artery balloon-catheter dilatation: review of Lenox Hill experience.

Operative transluminal coronary angioplasty (OTCA) has been used as an adjunct to coronary artery bypass surgery in 65 patients over a 56-month period beginning in May 1978. Experience has led us to use OTCA primarily in the left anterior descending coronary artery. The angioplasty catheter has undergone a number of modifications. Late restudy (8 to 56 months; mean, 24.1) data in 17 patients demonstrated that 15 of 19 angioplasty segments (78.9%) were patent.

Angioplasty, Balloon↗

[Brucellosis in children].

It has been studied in a series of 30 children affected of brucellosis, the most important epidemiologic, clinical and biologic characteristics. It has been emphasized the good response to the combined treatment of tetracycline and streptomycin.

Adolescent↗

[Intestinal parasitoses: contribution to their clinical diagnosis].

A fairly high number of symptoms are usually ascribed to intestinal parasites, a fact leading many times to various treatments in the absence of diagnostic evidence. Aiming to correlate presence of parasite with that of signs and symptoms authors have reviewed 1,131 patients submitted, for several reasons, to a search of parasites which was positive in only 384 cases. Authors conclude that only eosinophilia is a quite constant finding in E. vermicularis infestation and abdominal pain and chronic diarrhea are often present during giardia infestations.

Adolescent↗

Use of operative transluminal coronary angioplasty as an adjunct to coronary artery bypass.

Operative transluminal coronary angioplasty (OCTA) was used to improve coronary artery bypass graft (CABG) runoff in patients having complex segmental and diffuse coronary artery obstructions. OTCA was performed during CABG through the bypass arteriotomy on 64 arteries in 58 patients. An angioplasty system specifically designed for operative use was employed. In 13 cases, angioplasty was performed both proximal and distal to the coronary arteriotomy, for a total of 77 angioplasty sites. Elective restudy was performed on 36 angioplasty sites in 28 arteries in 24 patients: Sixteen patients were restudied between 18 and 21 days (mean 16) and eight between 4 and 32 months (mean 20.5). Patency rate, as assessed at each angioplasty site, was 86.1% (20/24 studied early and 11/12 studied late). Three coronary perforations (4.7%) occurred and were repaired without perioperative infarction or other sequelae. The one operative death (1.7%) occurred in a patient with preoperative refractory cardiogenic shock. There were seven perioperative infarctions (12.1%), of which three (4.7%) were in the distribution of the coronary artery undergoing OTCA. The favorable short-term and medium-term patency rates indicate that OTCA is a useful adjunct to CABG that permits more complete revascularization of small or diffusely diseased coronary arteries.

Adult↗

Cefaclor: clinical and bacteriological evaluation in 45 cases.

This report deals with studies of the effectiveness, tolerance and toxicity of cefaclor in the treatment of 45 patients with urinary tract infections (40 cases) and pneumonia (5 cases) caused by susceptible pathogens. Cefaclor was administered orally in a dosage of 1 to 3 g per day for 7 to 11 days. Clinical and laboratory examinations were performed before, during, at the end of treatment, and 4 weeks later in cases of urinary infection. All 5 patients with pneumonia and bronchopneumonia were cured. Clinical and bacteriological cures were obtained in 28 (70%) of the 40 cases of urinary tract infections. Identification and typing of microorganisms, disk sensitivity tests, minimal inhibitory concentrations and cefaclor blood levels also were determined.

Adult↗

Respiratory cryptosporidiosis: case series and review of the literature.

Five case of intestinal cryptosporidiosis with pulmonary involvement in patients with AIDS are reported. The diagnosis was based on the recognition of acid-fast oocysts in sputum or aspirated bronchial material and stool specimens. Coughing and excess secretions were present in all cases. Four patients had other associated pulmonary pathogens: two Mycobacterium tuberculosis, one Mycobacterium fortuitum and one Cytomegalovirus + Pneumocystis carinii; all of them had a previous (three cases) or simultaneous (one case) diagnosis of intestinal cryptosporidiosis, presenting with diarrhoea and vomiting. In the fifth patient Cryptosporidium was the only pulmonary pathogen found in a bronchial aspirate, and the onset of diarrhoea was 1 month after respiratory detection. Fifty-seven cases of respiratory cryptosporidiosis have been reported since 1980. In 17 of them, no other pathogen was found. Diarrhoea was present in 77% of the patients, cough in 77%, dyspnea in 58%, expectoration in 54%, fever in 45%, thoracic pain in 33%.

Acquired Immunodeficiency Syndrome↗