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Biomedical subjects

A Chinichian

Publications and source records attributed to A Chinichian.

4 recordsLinked to original sources

Postprostatectomy lithiasis.

After a short historical survey and a comprehensive review of the world literature which comprises 242 cases (including 19 personal ones), 10 new cases of lithiasis after prostatectomy are added (5 of which are personal ones), making a total of 252 cases. The CT scan was very useful in the diagnostic imaging. In appropriate situations, the use of the stone basket was found advantageous. In patients who are at risk of developing stones after prostatectomy, great care should be exercised both during the operation and in the postoperative period.

Aged

Duodenogastric reflux in patients with Barrett's esophagus.

The role of duodenogastric reflux in the pathogenesis of gastroesophageal reflux disease is not clear. Using hepatobiliary scanning techniques, we found evidence of duodenogastric reflux in six of 13 patients with Barrett's esophagus. This compares with only two positive studies in 19 control subjects. This difference is statistically significant (P = 0.038, two-tailed Fisher's exact test). Three of nine patients who had gastroesophageal reflux without Barrett's esophagus had evidence of duodenogastric reflux, a frequency not significantly different from either of the other groups. Gastroesophageal reflux of bile and pancreatic enzymes, in addition to gastric acid may contribute to the greater esophageal damage often seen in Barrett's esophagus. The presence of duodenogastric reflux in these patients may have important pathophysiologic and therapeutic implications.

Barrett Esophagus

Pancreatic pseudocyst with hemorrhage into the gastrointestinal tract through the duct of Santorini.

Hemorrhage into a pancreatic pseudocyst frequently goes unrecognized. This catastrophic event can be heralded by intermittent bleeding, or may present as massive gastrointestinal hemorrhage. A high index of suspicion, proper diagnostic workup, and prompt surgical management afford the patient the best chance for survival. We report a patient with massive pseudocyst bleeding into the gastrointestinal tract via the duct of Santorini and discuss the current diagnostic and therapeutic approach.

Cholangiopancreatography, Endoscopic Retrograde

Does the addition of methylene blue to the sclerosant improve the accuracy of injections during variceal sclerotherapy?

We evaluated the possibility that the addition of methylene blue to the sclerosant would improve the accuracy of intravariceal injections during endoscopic variceal sclerotherapy. Four patients had eight sessions of endoscopic variceal sclerotherapy with a sclerosant containing a combination of 3% sodium tetradecyl and 60% renograffin. For four sessions, 1 ml of methylene blue was added to 9 ml of sclerosant. The endoscopist judged each injection to be intravariceal or paravariceal. This was confirmed by fluoroscopy. There were 57 injections (28 with methylene blue, 29 without) in the eight sclerotherapy sessions. Intravariceal injections were confirmed fluoroscopically in 64.9% of injections (60.7% with methylene blue 69% without). The endoscopist correctly assessed intravariceal versus paravariceal injections 66.7% of the time (71.4% with methylene blue, 62% without). None of the differences approached statistical significance. The addition of methylene blue to the sclerosant does not improve the accuracy of intravariceal injections or the endoscopist's ability to recognize paravariceal injections during sclerotherapy of esophageal varices.

Esophageal and Gastric Varices