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Biomedical subjects

A Chays

Publications and source records attributed to A Chays.

At least 55 records · Page 3Linked to original sources

[Current imaging of vasculo-neural conflicts in the cerebellopontine angle].

UNLABELLED: To demonstrate the high sensitivity of high definition MRI and particularly "Constructive Interference in Steay State" (Ciss) imaging sequence, in depicting neurovascular conflicts in the CP angle cistern, cisternographic imaging and high definition T1 weighed (Turbo flash), contrast enhanced imaging were used to investigate hemifacial spasm (72 patients) and tinnitus with abnormal BER (5 patients). The study was complemented with Angio MR in 25 patients. The results were compared with findings in a control group of 200 patients, and with the surgical observations in 57 operated cases. In hemifacial spasm, the morphology of the neurovascular conflict was determined, as well as the site of compression (lateral medullary fossa 38 cases; nerve 9; both 15 cases), and the vessel involved (VA 25 cases; PICA 16 cases; AICA 10 cases; VA and PICA 8 cases; VA and AICA 3 cases; lateral medullary vein 1 case). In tinnitus (5 cases), the AICA was involved in every case in the IAM. Among 57 operated cases, only one false negative was observed. In the asymptomatic control group, a nerovascular conflict was observed in 3, 5% of the cases only. CONCLUSION: CISS imaging is the single most efficient technique, but the combined used of the 3 types of imaging brings the highest diagnostic efficiency, for identifying a neurovascular conflict in the CPA cistern.

Adult↗

Canal wall prosthesis--new devices.

In our experience, management of the troublesome mastoid cavity a "rehabilitation" of the middle ear, usually involves post canal wall reconstruction. The purpose of the long canal wall reconstruction is to restore the anatomy as perfectly as possible in order to induce satisfactory wound healing of both epidermal a mucosal layers. The numerous materials and different surgical procedures to date, demonstrate the difficulty of reconstruction of the ear canal. Over twenty years we have performed 386 cases using various materials: cortical bone, ear canal allograft, ceravital, porous and dense hydroxylapatite. More recently to improve the anatomical results we have used a new titanium prosthesis. The pros and cons of each device are discussed.

Biocompatible Materials↗

On the role of the olivocochlear bundle in hearing: a case study.

A young patient with normal pure-tone thresholds in both ears underwent a unilateral vestibular neurotomy in January 1992 to relieve severe vertigo ascribed to Ménière's disease. Evidence is provided that the whole vestibular nerve including the olivocochlear bundle (OCB) was sectioned. Just prior to the surgery, the patient was examined in several psychoacoustic tests involving mainly signal detection and selective attention. Over the next 20 months, he was reexamined in those same tests. The patient's ability to detect expected tones in the quiet (including audiograms) or in noise was the same as before the surgery. The one change was a marked improvement in the detection of unexpected signals in noise, which appears to reflect impaired selective attention. During those 20 months, new tests were also performed on discrimination, loudness, pitch, lateralization, and temporary threshold shift. On these tests, the only differences between the operated and unoperated ears concerned binaural diplacusis and loudness adaptation close to threshold, but these differences may well have been present prior to the surgery. Except with respect to what is probably selective attention, we uncovered no other clear role for the OCB in hearing. This outcome agrees with limited measurements on other patients, with their subjective reports, and with a number of published neurophysiological observations.

Acoustic Stimulation↗

[Role of endoscopy and vascular decompression in the treatment of hemifacial spasm].

Although it has long been hypothesized that hemifacial spasm could arise from a conflict between the nerve and the artery, it is very difficult to distinguish between a normal arterial loop and a pathological conflict leading to facial symptoms. Several new elements would help in the definition of the cause and allow less traumatic treatment of idiopathic hemifacial spasm. They include magnetic resonance imagery with CISS sequences, limited retrosigmoid approach, endoscopy of the cerebellopontine angle and monitoring the facial nerve. In our experience with 20 cases, retrosigmoid approach with a combined surgical and endoscopic procedure has led to total involution of the spasms in 80% of the cases.

Adult↗

Microfiberoptic evaluation of the middle ear cavity.

Endoscopic instruments have revolutionized surgical diagnosis and treatment. Recently, a high resolution microfiberoptic endoscope has been developed that has vast potential for otologic use. This microfiberoptic endoscope was used in cadaver and human studies to visualize the middle ear cavity. The technique used involved placing a 1.0-mm or smaller microfiberoptic scope into the middle ear via a tympanic membrane perforation, through a myringotomy tube or up the eustachian tube. Using the scope, the mesotympanum and hypotympanum can be well visualized. Similarly, the round window, oval window, ossicular chain, and related structures can be clearly demonstrated and recorded photographically. This technique has great potential to enhance diagnosis without open surgery.

Adolescent↗

Surgical perspectives of endoscopy of the cerebellopontine angle.

Owing to distal light and panoramic view, the endoscope expands the view inside the cerebellopontine angle without touching the cerebellum or the brain stem and allows clear identification of the vascular and nervous components crossing the cerebellopontine angle. Using a retrosigmoid approach with a combined surgical and endoscopic procedure, the surgeon gets more accurate information to visualize the adjacent structures to a small acoustic neuroma, to check the lateral part of the internal auditory canal, and to locate a vasculonervous cross-conflict. In the future, an endoscopic vestibular neurotomy or an endoscopic microvascular decompression seems to be a possible approach.

Cerebellopontine Angle↗

[Contribution of endoscopy of the cerebellopontine angle by retrosigmoid approach. Neuroma and vasculo-nervous compression].

An endoscopic approach to the cerebellopontine angle has been suggested by several authors over the last 20 years but it is only recently that the technical and operative conditions for successful endoscopy could be met. The retrosigmoid approach provides simple and direct access to the cerebellopontine zone. The endoscope, with its distal light source, provides excellent illumination of a wide visual field within an anatomical site particularly rich in neurovascular structures. Endoscopic and microsurgical techniques may be combined for the surgical management of acoustic neuroma with the advantage of assuring better exposure of structures adjacent to the tumor and better control of the quality of dissection of the fundus of the internal auditory canal. The addition of endoscopic techniques, during surgery for trigeminal neuralgia or unilateral facial spasm, makes it possible to accurately locate the site of neurovascular compression without either retraction of the cerebellum or unnecessary dissection.

Arteries↗

MRI exploration of the intrapetrous facial nerve.

We report our experience of intrapetrous facial nerve evaluation in 33 patients examined by three-dimensional MRI (3D-FT) with intravenous gadolinium injection. The examinations were performed by a 1 Tesla magnet, using Flash and Turbo-Flash sequences which enabled us to obtain contiguous millimetric sections and to make reconstructions in all planes. Among these 33 patients, 31 had facial palsy and 2 a facial nerve lesion without clinical signs and discovered by chance. Facial palsy had started rather abruptly in 26 cases. It was either idiopathic (n = 20) or caused by herpes zoster (n = 1), injuries (n = 2), metastasis (n = 1) and tumour (n = 1); it was concomitant with a granuloma in 1 case. Five patients seen or explored late had congenital cholesteatoma (n = 2), facial nerve neurinoma (n = 2) or persistent idiopathic facial palsy (n = 1). There was no contrast enhancement in "chronic" non tumoral facial palsy. All tumours (neurinoma, neurofibroma, metastasis) were contrast-enhanced, as were the 2 cases of traumatic palsy and the case with granuloma of the labyrinth. In acute idiopathic facial palsy (n = 20), contrast enhancement was demonstrated in 11 patients; among these, recovery was complete at 2 months in 1 case and incomplete in 9 cases; 1 patient was lost sight of. In the 9 patients without contrast enhancement, recovery was complete in 7; 2 patients were lost sight of. This study shows that minute lesions of the facial nerve can be detected with millimetric MRI T1-weighted sequences and contrast enhancement. It also suggests that contrast enhancement has some prognostic value in patients with acute idiopathic facial palsy.

Acute Disease↗

[Vestibular compensation. Clinical value of its dynamic study].

Vestibular compensation consists of all the processes of neurological reorganization that allow recovering balance after a unilateral vestibular lesion. According to its etiology, the peripheral lesion may be more or less severe, may evolve more or less rapidly, and be more or less reversible. Therefore, it will have a characteristic "pattern" in time, which enables us to classify the kinetic aspects of peripheral pathology. Vestibular compensation, which responds to these variations in the sensitivity of the posterior labyrinth, is a slowly progressive adaptation mechanism. This compensation will progressively reduce the musculotonic asymmetry affecting the postural muscles and the eye muscles, and it can therefore be studied on the basis of the velocity of the spontaneous nystagmus as measured in the dark. We can then define a "vestibular compensation rate" at a given moment. To achieve this, a diagram (E. UMER) is proposed to represent the lesion and the rate of vestibular compensation and to study their mutual relationships. The dynamic study of vestibular compensation and the measurement of its "time constant" than have threefold merits for diagnosis, prognosis and treatment.

Adaptation, Physiological↗

Vestibular neurotomy by retrosigmoid approach: technique, indications, and results.

During the past 15 years, 96 retrosigmoid vestibular neurotomies have been used in the surgical management of incapacitating Meniere's disease for the control of vertigo and preservation of hearing. This posterior approach of the pontocerebellar angle gives the best view on the acousticofacial nerve bundle, through a 2 x 2 cm suboccipital craniotomy immediately behind the mastoid and sigmoid sinus. Then the vestibular nerve is easily identified, separated from the cochlear nerve and sectioned, the facial nerve not being at risk, as it lies much deeper. Actually, the majority of authors agree that vestibular neurotomy is the most effective surgical treatment in relieving disabling vertigo (96% of cases) with serviceable hearing, but few surgeons know that the retrosigmoid approach is simpler and more reliable than the middle fossa or retrolabyrinthine approaches, with a low incidence of complications. The purpose of this paper is to emphasize the routine use of the retrosigmoid approach.

Aged↗

[Anatomo-pathology of cholesteatoma].

The authors, from their own histopathological studies and from an overview of otological literature focus the controversial problems about the so-called disease cholesteatoma. The history of cholesteatoma has been marked out by pathologic data which, initially caused the cholesteatoma to be identified as a keratinized squamous tumor. This misnomer will however be retained because of it long-established usage. "Skin in the wrong place" in the middle ear summarizes this clinical entity. Electron microscopic observations provide arguments in favour of the migratory theory and the invasion of the epidermis from the bottom of the external ear canal into the middle ear cavity (identical fine morphology between skin and cholesteatoma, presence of Langerhans and Merkel cells, sharp junction between the advancing front of the cholesteatoma and the middle ear mucosa). Recent immunohistological techniques allow consideration of cholesteatoma as a self-induced inflammatory process in response to tissular and cellular conflicts. A cholesteatoma could be merely a non-healing wound process and a disease of epidermal growth control occurring in the middle ear space. The logical principles governing cholesteatoma surgery, suggested by these biological considerations, are: total removal of cholesteatoma matrix, prevention of cholesteatoma recurrence by a careful respect of the barrier separating the middle ear mucosa from the skin-lined bony external ear canal, maintenance of good healing conditions for both mucosa in a closed well-ventilated middle ear and epidermis in a harmonious anatomical external canal.

Cell Movement↗

[Otospongiosis: different surgical technics, identical results. Why?].

Both platinectomy and platinotomy are currently used to treat otosclerosis surgically. Though the techniques are different from one another, especially by the new area ratio between tympanic membrane and stapes foot-plate, the results are similar. It should be clear that the simple "piston model" of the tympanic ossicular system cannot explain this results. If, for the seesaw mechanical view, a vibratory molecular system conducting acoustic energy is substituted, a pertinent explanation can be given for this result. Thus, understanding of the pattern motion of the tympanic ossicular system has to change drastically.

Ear, Middle↗

[Retraction pockets, pathological entity?].

Retraction pockets are not a pathological entity per se but take after various ear diseases, with which they share the same morphological eardrum alterations. The authors believe that any holistic evaluation of retraction pockets, as though these were forming a single group of like pathogenic origin, i.e., tubal dysfunction, would be artificial and raise therapeutic problems. The statistical analysis of the causes for retraction pocket formation provides little information. Otologists are still looking into chronic otitis media and cholesteatoma as a possible, long-suspected, unproved etiology. Electron microscopy and, more particularly, istological-enzymological analyses of mounts prepared by the authors have shown, in some cases, the anomalous presence, in the pocket, of Langerhans' cells, which the authors consider as strongly indicative of cholesteatoma. While confirming the clinical diagnosis, anatomopathological examination allows to differentiate poor-prognosis retraction pockets from benign ones. The pathogenesis of these pockets is still poorly understood. It is the authors' contention that tympanic invagination is more likely traceable to some biopathological/biochemical phenomenon than to occupational mechanical disorders involving the tube. The clinical characteristics of retraction pockets are the basis for their classification into three groups, according to their evolutional tendency. Thus, developing cholesteatomas bear a poor prognosis; sequelae of benign otitis are associated with small risk; lastly, there is a small group of pockets the evolution of which is hard to specify. The authors believe that such differentiation between retraction pockets is mandatory to have a clear picture of therapeutic indications, and to assess the various outcomes.

Cholesteatoma↗

[Endoscopy of the eustachian tube. 1st evaluation].

The authors present a novel, original method for exploration of the middle ear cavity using Eustachian tube endoscopy. The diameter of the fibre optic tube was only 0.9 mm, hence the term micro-endoscopy. This endoscopic procedure was used during surgery for chronic otitis, where there was evidence of tubal etiology which required confirmation. The preliminary results are presented.

Ear Diseases↗

[Wegener's granulomatosis. Contribution of computed tomography and nuclear magnetic imaging].

Amongst the endothoracic forms of Wegener's granulomatosis, tracheal, bronchial and above all mediastinal localisations are unusual. Such a case having a bad outcome is reported here. Computed Tomography (TDM) was used to assess the extend of pulmonary parenchymal involvement. Magnetic Resonance Imaging (MRI) was superior to TDM for showing transmural infiltration of the tracheal and the origin of main bronchi.

Bronchial Diseases↗

[Diagnostic and therapeutic problems in dissociated forms of Menière's disease].

The authors report the cases of 5 subjects who presented with incapacitating vertigo which was attributed to a dissociated form of Meniere's disease. They stress the difficulty, in these circumstances, in making a precise diagnosis which can only in fact be confirmed with the benefit of a longer follow up. They stress the value of systematically combining frequency analysis with measurement of maximal slow phase velocity during vestibular testing. This allowed better precision in terms of topographical diagnosis. All subjects underwent vestibular neurotomy via the retro-sigmoid approach. The procedure did not alter hearing and compensation occurred within the usual delay. The question therefore arises as to when is the best time to intervene in patients presenting with vertigo of peripheral origin with preserved hearing.

Audiometry↗