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Biomedical subjects

A Chamorro

Publications and source records attributed to A Chamorro.

At least 73 records · Page 4Linked to original sources

[Limb shaking and loss of consciousness: a carotid-basilar artery syndrome].

We describe the brain MRI and cerebral blood flow characteristics in a patient with hypertension, severe bilateral carotid artery disease and moderate vertebrobasilar atheromatosis. When standing, the patient experienced short repetitive episodes of loss of consciousness and involuntary shaking of the lower extremities. We believe that, in this patient, the combination of bilateral perfusion insufficiency through the carotid artery, the local effects of atheromatosis of the penetrating branches arising from the basilar artery and the systemic effects of orthostatic hypotension may have caused ischemic lesions in the terminal zones of the paramedian branches of the basilar artery.

Carotid Artery Diseases↗

Posthypoxic myoclonus in intensive care.

Posthypoxic myoclonus (Lance-Adams' syndrome) is a rare complication of cardiorespiratory arrest. It has a better prognosis than other movement disorders secondary to brain ischaemia. We report a case of posthypoxic myoclonus in a 66-year-old woman after acute myocardial infarction and cardiopulmonary arrest. She had action and intention myoclonus, and these movements were also initiated by acoustic and pain stimuli. The origin of the myoclonus was probably subcortical, and it improved with clonazepam 2 mg t.i.d. We emphasize that early diagnosis is necessary in intensive care units in order to avoid misinterpretation of this syndrome and to start appropriate treatment.

Aged↗

[Current diagnosis of renal cancer: clinical experience with 71 cases].

The diagnosis of renal cell carcinoma was frequently delayed due to the anatomic location of kidneys. Recently, the development of echographic imaging techniques has drastically changed this situation. In this retrospective review of 71 patients with renal cell carcinoma, the diagnosis was made incidentally during a routine abdominal ultrasound examination in 49% of cases. These patients, has lower stage and smaller tumors than symptomatic patients. Among the latter, hematuria was the principal presenting symptom. The early diagnosis of renal cell carcinoma allows more conservative surgical procedures and has a favorable effect on long term survival.

Adult↗

Clinical-computed tomographic correlations of lacunar infarction in the Stroke Data Bank.

Lacunar stroke was diagnosed in 337 (26%) of the 1,273 patients with cerebral infarction among the 1,805 total in the Stroke Data Bank. We analyzed the 316 patients with classic lacunar syndromes. Among these, 181 (57%) had pure motor hemiparesis, 63 (20%) sensorimotor syndrome, 33 (10%) ataxic hemiparesis, 21 (7%) pure sensory syndrome, and 18 (6%) dysarthria-clumsy hand syndrome. No striking differences were found among the risk factors for the lacunar subtypes, but differences were found between lacunar stroke as a group and other types of infarcts. Compared to 113 patients with large-vessel atherosclerotic infarction, those with lacunar stroke had fewer previous transient ischemic attacks and strokes. Compared to 246 with cardioembolic infarction, patients with lacunar stroke more frequently had hypertension and diabetes and less frequently had cardiac disease. We found a lesion in 35% of the lacunar stroke patients' computed tomograms, with most lesions located in the internal capsule and corona radiata. The mean infarct volume was greater in patients with pure motor hemiparesis or sensorimotor syndrome than in those with the other lacunar stroke subtypes. In patients with pure motor hemiparesis and infarcts in the posterior limb of the internal capsule, there was a correlation between lesion volume and hemiparesis severity except for the few whose infarct involved the lowest portion of the internal capsule; in these patients severe deficits occurred regardless of lesion volume. Taken together, the computed tomographic correlations with the syndromes of hemiparesis showed only slight support for the classical view of a homunculus in the internal capsule.

Aged↗

Hemodynamic role of ophthalmic artery collateral in internal carotid artery occlusion.

We performed duplex and transcranial Doppler studies in 36 patients with angiographically documented internal carotid artery occlusion (ICAO) to determine the effect of ophthalmic artery collateral (OAC) on measures of vascular resistivity both proximal and distal to the occlusion. Resistance in the common carotid artery, measured by the resistivity index, was significantly lower in the group with OAC than in those without OAC, indicating a shunt to the low resistance intracranial circuit. The pulsatility index (PI) of the Doppler signal in the ipsilateral middle cerebral artery, a measure of both inflow pressure and distal vascular resistance, did not differ between those with and without OAC. However, the presence of circle of Willis collateral pathways (anterior communicating and/or posterior communicating artery) did appear to have a significant effect on pulsatility. When both were present angiographically, PI was higher than in the group with only 1 Willisian collateral. These findings suggest that OAC has a marginal effect on vascular resistance in arterial bed distal to an ICAO, while Willisian collaterals appear to have a more important role in cerebral perfusion, as measured indirectly by Doppler methods.

Analysis of Variance↗

Visual hemineglect and hemihallucinations in a patient with a subcortical infarction.

An alcoholic patient with a mainly right subcortical infarction developed contralateral left-sided neglect and then, in the context of alcohol withdrawal, unilateral hallucinations in the non-neglected right hemispace. It is hypothesized that an interruption of the striatocortical pathways could prevent the right hemisphere from representing appropriately internally produced stimuli.

Adult↗

[Primary hyperparathyroidism: usefulness of high resolution echography in local diagnosis].

Recent reports show a better surgical outcome in primary hyperparathyroidism when an accurate preoperative localization of the lesion in available. We performed high resolution sonography in 23 consecutive patients (20 women) with biochemically proven hyperparathyroidism. Twenty two of them were operated on and their sonographic reports were compared to the surgical and pathological findings (20 adenomas, 1 carcinoma and 1 hyperplasia). One patient did not have surgery but the sonogram was compared to a Tl 201-Tc99 scintigram that suggested an adenoma. Sonography showed a single parathyroid tumor in 17 patients and failed to demonstrate a lesion in six. There were two false positives and 6 false negatives. The sensitivity was 71.5% and the positive predictive value was 88%. Three out of 6 patients with a negative sonography had an adenoma located out of reach for the method. Our results show that the high resolution sonography is a useful, non invasive method to localize abnormally enlarged parathyroid glands in hyperparathyroidism and we think it should be performed in every patient with a biochemical diagnosis of this disease.

Adult↗

[Duodenal reticulosarcoma (an unusual case of primary duodenal tumor)].

A rare case of primitiv mesenchimatous neoplasm of the duodenum is presented. After a review of the few cases reported in the literature, the authors emphasize the unspecificity of the clinical features and the diagnostic reliability of the fibroendoscopy. Alterations of the cellular immunity were presented in this case. The restricted posibilities of treatment in these highly malignant tumors are also discussed.

Aged↗