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Biomedical subjects

A Chahtane

Publications and source records attributed to A Chahtane.

11 recordsLinked to original sources

[Gestational trophoblastic diseases. Apropos of 105 cases].

The authors report a retrospective study of 105 observations of gestational trophoblastic diseases managed at the university clinic of obstetric gynecology I (Pr Chaoui). Of this study, one listed 72 cases of complete mole hydatiforme with 5 cases of sacrofetal pregnancy. The invasive mole is found in 4 cases and the choriocarcinoma in 24 cases. The general frequency of this pathology is of 1/770 pregnancies. The age of our patients varies from 15 to 52 years with an average age 27 years and the multiparity is found in 50% of the cases. 103 patients (95.5%) consulted for metrorrhagia associated pelvic pains in 31 cases (30%). The toxic syndrome was present in 20 patients (12%) with a preeclampsy in 6 cases (5.71%). The physical examination showed a very increased uterus of size in 92 cases (87.5%) associated adnexal mass in 37 cases (35.2%). The diagnosis was especially echographic in the totality of the cases associated or not with a proportioning of plasmatic beta HCG or prolans urinary. The treatment of the trophoblastic disease varies simple endo-uterine aspiration (85%) until the chemotherapy treatment (32.4%), the hysterectomy was indicated in a third of the cases. The evolution of the non complicated mole hydatiforme was good in 100% of the cases, it quasi totality of the invasive moles presented a complete remission. Among the 24 choriocarcinoma, we deplore 4 deaths in a table of pulmonary, hepatic and cerebral metastases. In order to improve the forecast of these diseases, the diagnosis must be early with an adequate treatment and a rigorous monitoring.

ABO Blood-Group System↗

[Malignant schwannoma of the breast. A case report].

Malignant schwannoma is a very rare sarcomatous tumor of unknown etiology. Primary mammary localization is exceptional. Clinically, the tumor manifests as an isolated painless nodule visualized as a benign nodule on standard radiogram. Positive diagnosis is provided by pathology. Treatment is surgical. The risk of local recurrence imposes a radical treatment. We report one case and review the literature, underlining the difficulties encountered in diagnosis and emphasizing the recurrent nature of this tumor after conservative treatment.

Adult↗

[Krukenberg's tumors. 9 cases. Review of the literature].

The authors report a series of nine cases of Krukenberg's tumor, operated at the university clinic of obstetric gynecology (Professor Chaoui) during a period from 1977 to 1990. They underline the metastatic character of this tumor, whose primitive lesion is very often digestive. In most cases, the diagnosis is set late by histological study of the operatory piece, showing the revealing character of this tumor. All the authors agree upon the very dark prognostic of this tumor. The only hope of improvement lies in an extraction as soon as possible of the primitive tumor, followed by a radical treatment of the ovarian tumor. The contribution of complementary treatment is questionable; however, adjuvant chemotherapy keeps a positive efficacy, according to certain authors. The authors deplore one death in keeping with a late diagnosis.

Adult↗

[Ovarian pregnancy. Four cases with review of the literature].

The authors report four cases of ovarian pregnancies operated in Central Maternity of Rabat (Pr Chaoui) during a period from 1979 to 1989. In the light of literature data, they have tried to trace out the particularities of this form of extra-uterine pregnancy. Clinical symptomatology of ovarian pregnancy very often remains similar to that of tubary GEU as well as the data of complementary exams with the exception sometimes of coelioscopy. The treatment, because of diagnostic delay, is annexectomy in all cases. But it is desirable to carry out a conservative treatment in the form of partial ovariectomy. Only pathological anatomy can give the diagnosis a sense of certainty.

Adult↗

[Hydatidiform mole and its complicated development].

The authors report a series of 260 cases of trophoblastic disease, followed up over a period of 18 years. Supervision was based on clinical findings, biological development, radiology and ultrasound. The outcome was favourable in 80% of cases with 2.7% requiring prophylactic hysterectomy for classifical hydatiform mole. In the other cases (20%) the following was the way the disease developed: 12 cases of persistent trophoblastic activity, 13 cases of invasive mole, 24 cases of choriocarcinoma. Initially the treatment was with chemotherapy and surgery was used as an extra treatment in 14% of cases, which gave encouraging results. The authors regret three deaths in this series following choriocarcinoma. Two of these were after chemotherapy as a sole treatment and one after treatment with chemotherapy and surgery.

Adolescent↗

[Malignant non-Hodgkin's lymphoma of primary mammary localization. Two cases].

The authors report two cases of non-hodgkinian malignant lymphoma (NHML) of primitive mammary localization. Surveying the data of world literature, they have tried to trace the main characteristics of this breast cancer. The NHML are met at all ages, of female predominance and whose clinical aspect is summarized in two great tables: a module radiologically benign, isolated, quite limited, or a tumor of inflammatory aspect. Anatomopathological exam and the extension check-up constitute a fundamental step to establish the diagnosis, to confirm the initial localization and evaluate the prognosis which depends on two main factors: anatomical stage and histological type. Chimiotherapy is indicated initially, often related to a conservative surgery (tumorectomy), rarely to a radiotherapy.

Adult↗

[Hypertrophic tuberculosis of the cervix. Three cases].

Tuberculosis of the cervix of the uterus is a rare form of genital tuberculosis. The epidemiology does not have any particular specific feature; but the macroscopic appearance gives a first impression of a cancer. Only by carrying out a biopsy of the cervix, followed by study of the histology can the problem be solved so that longterm anti-tuberculous treatment can be started. There is rarely any need for surgery, that only in cases resistant to medical treatment. The authors report three cases of tuberculosis of uterine cervix, found in the university clinic of obstetrics and gynaecology I (Professor Chaoui) during the years 1986-90. The incidence of this condition is 8.5% of genital tuberculosis. The outlook is good with full healing if the treatment is carried out properly.

Adult↗