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Biomedical subjects

A Chagnon

Publications and source records attributed to A Chagnon.

144 records · Page 8Linked to original sources

[Malignant adrenocortical tumor as a part of Wermer's syndrome. Apropos of a case].

The authors report a case of malignant adrenal carcinoma associated with nodular adrenal hyperplasia as part of Wermer (N.E.M.I.) type pathological polyendocrinopathy syndrome. They stress the prognostic importance of the glandular degeneration and the type of adrenal involvement in these "multiple endocrine neoplasia".

Adrenal Cortex Neoplasms↗

[Isolation of viruses in the cerebrospinal fluid in a case of acute varicella meningo-encephalitis].

The authors report a case of severe, life-threatening, meningo-encephalitis occurring in a young nonimmunodepressed adult with varicella. The demonstration of a cytopathogenetic effect of his cerebrospinal fluid and of immunoglobulins M specific to the varicella-zoster virus was in favour of an acute, directly viral-dependent encephalitis rather than an immune-mediated leucoencephalitis, as used to be commonly admitted. This is an incitement to use acyclovir in such cases, the effect of which contributes to reinforce this pathogenic hypothesis.

Adult↗

[Recurrent attacks of facial neuralgia (author's transl)].

The author reports one case of sedation by tiapride of severe and recurrent attacks of facial neuralgia. Knowing the rather poor therapeutic means for this disease, it is suggested to extend the use of this recent neurotropic drug to this purpose.

Aged↗

[Detection of IgM by immunofluorescence: application to rubella].

Thirty couples of serum and thirty-five individual sera were tested for the presence of rubella-specific IgM by indirect immunofluorescence. BHK21 cells cultivated on "Lab-tek" were used as an antigenic support. Specific IgM were significantly high in subjects with increased antibody complement fixation or hemagglutination inhibition. Identical findings were observed in a pregnant women having contracted rubella during the seventh month of pregnancy.

Fluorescent Antibody Technique↗

[Chronic lymphocytic leukemia, acute anergic tuberculosis, multiple caseous adenitis (author's transl)].

The authors report an exceptional case of hematopoietic tuberculosis complicating a chronic lymphocytic leukemia, developing at first an acute tuberculous septicemia then a caseous disease of lymph glands. The usual difficulties of the diagnosis were increased by the underlying blood disease and it was done mainly thanks to an osteo-medullary biopsy and to the results of the specific proof treatment.

Aged↗

[Vectorcardiography in the diagnosis of the association of inferior necrosis--left intraventricular conduction disorders].

The authors study 53 vectorcardiograms (VCG) which demonstrate the association of inferior myocardial necrosis with left intraventricular conduction disturbances (LIVCD) consisting of 44 left anterior hemi-blocks (LAHB), 2 left posterior hemi-blocks (LPHB) and 7 complete left branch blocks (CLBB). In the presence of LAHB, the ECG and VCG diagnosis concur in 37 cases, with a more obvious appearance on the VCG in 16 cases. In 7 cases, only the VCG provided the diagnosis of this association. In the presence of LPHB, the ECG, in one case, only showed signs of necrosis and only the VCG revealed the hemi-block; in the other case, the ECG showed signs of LPHB, but the Q waves did not present the criteria of necrosis. Once again, only the VCG provided the diagnosis of the association. Finally, in the presence of CLBB, the diagnosis were in agreement in only 3 cases. In two cases, only the VCG revealed the necrosis, in one case, the ECG was superior and in the remaining case, the ECG and the VCG were equally ineffective in confirming the inferior necrosis which was nevertheless definitely present. On the basis of these findings, the authors discuss the ECG criteria of the association of inferior necrosis and LIVCD.

Cardiomyopathies↗