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Biomedical subjects

A Cerene

Publications and source records attributed to A Cerene.

At least 37 records · Page 2Linked to original sources
PubMed1985

[Disobliteration of coronary arteries by the laser. Peroperative experience].

The authors report their experience of coronary artery disobliteration by laser in 10 patients. This was a preliminary study to assess the effects of an Argon laser on atheromatous coronary stenosis in vivo. This technique was used during coronary bypass surgery. Two series of patients were treated: an initial group of 5 patients who underwent laser therapy associated with coronary bypass surgery; a second group undergoing laser therapy alone without distal bypass grafting. The results were assessed by immediate angiography in the first series and by the passage of calibrated probes in both series. Secondary control angiography after 3 weeks was carried out in all patients. The immediate results showed a constant improvement (less than 25%) in the degree of stenosis. However, secondary angiography showed secondary occlusion in 88% of cases. These preliminary results show: the immediate efficacy of Argon laser in reducing the size of atheromatous plaques, the innocuity of the method as there were no postoperative deaths, a high incidence of secondary failure which could be related to the type of indication (competitive flow in the first group and poor distal run off in the second group of patients) or to the type of laser used. The authors consider this to be a promising technique but a lot of clinical and experimental work remains to be done before it can be adopted for routine use.

Aged↗
PubMed1985

[Indications and results of combined urokinase-lys plasminogen in acute ischemic pathology of the legs].

Low dose urokinase-lys plasminogen was used to treat 10 patients with acute ischemia of lower limbs. Preliminary results are reported and indications defined, the combination producing effective relief and being very well tolerated biologically and clinically. All patients presented clear signs of ischemia provoking a short term risk for the limb. Direct femoral puncture arteriography of the ischemic limb was an essential pretreatment investigation. A thin catheter left in contact with the thrombus allowed localized fibrinolysis to be performed. Follow up arteriography examinations assessed clinicopathologic results, while biologic surveillance of principal coagulation parameters showed a lack of significant alterations during treatment. Ischemic signs were totally relieved in 7 cases, with arterial repermeabilization allowing recuperation of one (3 cases) or both (2 cases) distal pulses. Persistence of a popliteal thrombus in one case required a fogarty after a direct approach and the limb was saved. Two patients had to be amputated because of delayed treatment. These encouraging results suggest that this procedure of local thrombolysis be reserved for popliteal or infra-popliteal occlusions accompanied by sensory-motor signs and of recent (less than 72 hours) onset. Follow up for 8 months is insufficient but has shown the absence of deterioration, but this is obviously a function of the natural course of the underlying atheromatous disease.

Acute Disease↗
PubMed1984

[Prospective study of the long-term permeability of the internal saphenous vein and of polytetrafluoroethylene in the lower femoro-popliteal bypass. Results after 5 years in 100 patients].

Autogenous saphenous vein (ASV) (50 patients-group I) was compared to polytetrafluoroethylene (PTFE) (50 patients group II), in 100 below-knee femoropopliteal bypass (FPB) procedures performed for limb salvage during à 5 year-period. PTFE was used as an alternative procedure in the absence of a suitable ASV. Each group made of 50 patients was not significantly different from the other. The mean follow up period for patent graft is now 35 months (12-60 months) and the overall life table cumulative patency at 5 years, is 65% in group I and 18% in group II (P less than 0.05) whereas the limb salvage rate (LSR) is 81% with ASV and 26% PTFE (P less than 0.05). No correlation was demonstrated between patency and run-off. The graft described was used in elderly patients most of whom would have had amputation before the introduction of PTFE. Theses results advocate the use of PTFE only in secondary intention and never to shorter operation time.

Aged↗
PubMed1984

[Aneurysm of the infrarenal abdominal aorta in octogenarians. Apropos of a series of 30 consecutive cases].

UNLABELLED: The authors report a series of 30 operated consecutive infrarenal abdominal aneurysms on patients aged of 80 years old or more. The operation is necessary in emergency in 13 cases (43.3%): 10 patients with sudden severe abdominal pain and faintness and 3 with rupture. In 17 cases the indication of surgery is "elective" (56.7%): sole physical finding in 10 cases, one case of ureteral tract compression and 6 cases of recent pain. In 13 cases, the infrarenal aneurysm is associated with arterial occlusive disease. In 20% of the cases, the operation consists on aorto-aortic bypass graft; in the other cases, aorto iliac bypass is necessary; in 3 cases the distal implantation of the graft is on the groin, on the femoral artery. The hospital mortality is 20% of the cases (6 cases); after operation in emergency the mortality is higher (30.6%) than after elective surgery (11.7%). The mean of the late follow up is of 39 months (2 months to 9 years): the late mortality is 16.6% of the cases (5 cases). The actuarial percentage of survival at 4 years is 60%. CONCLUSION: The elderly is not a contraindication for surgical treatment of the infrarenal aortic aneurysm. The late survival rate is good after the operation.

Aged↗
PubMed1983

Clinical results of the aortic Medtronic-Hall prosthesis.

Between July 1979 and June 1982 we implanted aortic Medtronic-Hall prostheses in 40 patients. Ages ranged between 25 and 75, with a mean of 56 years. There were 38 cases of elective surgery (group I) and 2 acute aortic dissections (group II). All patients received anticoagulant medication. Follow-up ranged between 8 and 39 months with a mean of 22.5 months. Excluding operative mortality (7.5%) the 2-year actuarial survival rate is 97.2%. No death was related to the valve or its dysfunction. The overall thromboembolic rate is 0.78 per 100 patient years. No thromboembolic episode occurred in group I. No hemolysis was encountered and most patients experienced marked postoperative improvement. We consider that aortic Medtronic-Hall valves are valuable but further studies are necessary to confirm the results we obtained.

Adult↗
PubMed1978

Spontaneous renal arteriovenous fistula and arterial hypertension--conservative treatment and healing.

A case is reported of idiopathic renal arteriovenous fistula in a young adult suffering from arterial hypertension. It was treated by conservative surgery with endo-aneurysmorrhaphy and extrasinusal clamping of the artery supplying the fistula. The post-operative course was uneventful. Arterial pressure returned to normal after 30 months. Diagnosis, therapy and the relationship between hypertension and fistula are discussed.

Arteriovenous Fistula↗