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Biomedical subjects

A Castillo

Publications and source records attributed to A Castillo.

At least 127 records · Page 7Linked to original sources
PubMed1980

Tetanus in the adult: intensive care and management experience with 233 cases.

Over a period of 10 years, 233 adult patients were treated for severe tetanus in this ICU. Criteria of severity, clinical patterns, and a detailed plan of treatment are outlined. The authors emphasize that such treatment implicates the permanent availability of trained personel in handling cardiorespiratory emergencies as well as prolonged mechanical ventilatory assistance in a specially designed environment (ICU). The form of therapy described herein seems to be the best currently available management regime, inasmuch as it can be expected to reduce significantly the notoriously high mortality associated with severe tetanus. Although this therapy is very expensive and time consuming, this is the price to be paid when the life of one of these patients is endangered. Complications are usually bizarre and unexpected. The authors found a high incidence of infectious respiratory complications, probably related to a change in the tracheal flora secondary to antibiotic therapy and a less than ideal care of tracheostomies. Unexpected cardiac arrest was the most common cardiovascular complication and also the most common cause of death; in the majority of these cases, a satisfactory explanation for this complication was not found, but it could have been related to overactivity of the autonomic nervous system.

Anti-Bacterial Agents↗
PubMed1975

[Recording of conduction tissue potentials in intraventricular conduction disorders. (apropos of 147 patients)].

147 patients, 31 controls and 116 patients with intraventricular conduction disturbances, have been submitted to an endocardial investigation: HR lengthening in case of bundle-branch block indicates a low diffusion of the conduction disturbances and has a pejorative signification. The most important legthenings of this interval have been observed in the cases with delay in the common trunk of His bundle: -- In case of trunkular delay, 66% of the patients have a HR interval longer than 80 msec, and the average value of HR is 82 msec. -- In the absence of obvious trunkular delay, 8% of the patients only have a HR interval longer than 80 msec, with an average value of 67 msec. For these latter patients no branch potential was recorded. -- In some cases one is certain of the presence of a conduction disturbance of both branches and the HR value then never exceeded 60 msec. -- Branch potential recording makes it possible to determine the site of the conduction disturbance of the branch and show mild variations of the HR interval and of both components.

Action Potentials↗
PubMedDate not supplied

Effects of subconjunctival methylprednisolone on the blood aqueous barrier following cataract surgery.

The aim of this double-blind randomized study was to assess the effect of subconjunctival methylprednisolone hemisuccinate (MH) on the recovery of the blood aqueous barrier (BAB) following uncomplicated cataract surgery performed by the same surgeon in normal eyes. Fifty eyes of fifty patients (28 female, 22 male, mean age 72.3 +/- 11.2 years) were randomized into two groups: group 1 received a subconjunctival injection of MH (40 mg in 0.5 cc) at the end of the surgery and group 2 did not. All patients were free of other ocular or systemic diseases known to alter the BAB and were not taking any anti-inflammatory medications. Postoperative treatments were similar in both groups. The patients were submitted to laser flare photometry 30 minutes to one hour after mydriasis with a drop of tropicamide preoperatively and on the first, second and seventh day and then one month and six months following surgery. No difference in aqueous flare was seen between the two groups on any of postoperative visits. These data suggest that subconjunctival MH has no beneficial effect in postoperative BAB permeability following uncomplicated cataract surgery in normal eyes.

Aged↗