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Biomedical subjects

A Castillo-Fenoy

Publications and source records attributed to A Castillo-Fenoy.

34 records · Page 2Linked to original sources

[Studies of nodal conduction].

Nodal conduction has been studied in 44 normal subjects, 21 cases of 1st or 2nd degree AV block, 16 cases of LGL syndrome, and 19 patients with a distal infra-His AV block, by means of stimulation which was increased in regular steps of 5 beats per minute, and of extra-systolic stimulation. These two techniques demonstrate that the nodal response to an extrasystole or a regular tachycardia is not the same, and that different mechanisms are probably at play. With regular stimulation, the normal limits of 1/1 conduction lie between 140 and 200 per minute. A nodal block for a rate less than 130 per minute can be taken as indicative of a nodal defect. Delayed AH conduction is a much less precise criterion. It may reach a high level in normal subjects, and it is not certain that the finding of a PR interval of more than 200 msec. (AH of more than 140 msec.) at a normal rate is neccessarily indicative of nodal pathology. Cases of LGL syndrome are associated with short-circuits which are usually partial. The diverse responses observed in these different groups can be explained by modifications of structure within the A/V node itself.

Aged↗

[Second degre Wenckebach phenomenon. Electrocardiographic and clinical study apropos of 10 cases].

Study of atrio-ventricular conduction across the atrio-ventricular node using rapid atrial stimulation revealed a particular kind of block in 10 patients; the characteristics of the Wenckebach phenomenon were associated with a 2/1 block. One P wave was blocked, and the PR interval of the conducting sequence became progressively longer until the cycle was broken by two consecutive blocked P waves. By recording the potentials in the bundle of His, it proved possible to localise the conduction defect to the A/V node in 9 cases. The defect appeared in various clinical forms: atrial tachysystole, incomplete atrio-ventricular block, both chronic and acute, and atrio-ventricular conduction that was apparently normal. Study of the transmission through the node of progressively increasing atrial stimuli showed that there was a strong tendency towards diminishing conductivity which appeared to favour dispersion of the incoming impulses centrally within the node.

Adolescent↗